AAV	Adeno-associated virus
AFP	Alpha-fetoprotein
AKT	Protein kinase B
ASO	Antisense oligonucleotide
AUC	Area under the curve
CAM	Chorio-allantoic membrane
CAF	Cancer-associated fibroblast
CH	Chronic hepatitis
CHB	Chronic hepatitis B
DEN	Diethylnitrosamine
DFS	Disease-free survival
DNMT1	DNA methyltransferase 1 (gene symbol)
DNA	Deoxyribonucleic acid
EGFR	Epidermal growth factor receptor
EMT	Epithelial–mesenchymal transition
EV	Extracellular vesicle
FDG-PET	Fluorodeoxyglucose positron emission tomography
FASN	Fatty acid synthase (gene symbol)
GEMM	Genetically engineered mouse model
G6PD	Glucose-6-phosphate dehydrogenase
G6PC	Glucose-6-phosphatase
HDAC	Histone deacetylase
HCC	Hepatocellular carcinoma
HBV	Hepatitis B virus
HCV	Hepatitis C virus
HK2	Hexokinase 2 (gene symbol)
HIF-1α	Hypoxia-inducible factor 1 alpha
IL-6	Interleukin-6
LDHA	Lactate dehydrogenase A
LNA	Locked nucleic acid
LNP	Lipid nanoparticle
LP	Liposome (carrier)
miRNA	MicroRNA
mTOR	Mechanistic target of rapamycin
NAFLD	Non-alcoholic fatty liver disease
NASH	Non-alcoholic steatohepatitis
NP	Nanoparticle
ONC	Oncogenic
OS	Overall survival
OTT	Onset To treatment
OXPHOS	Oxidative phosphorylation
PAK4	p21-activated kinase 4
PBX3	Pre-B-cell leukemia homeobox 3
PD-1	Programmed cell death protein 1
PD-L1	Programmed death-ligand 1
PDK1	Pyruvate dehydrogenase kinase 1
PET	Positron emission tomography
PI3K	Phosphoinositide 3-kinase
PKM2	Pyruvate kinase isozyme M2
PPP	Pentose–phosphate pathway
PTEN	Phosphatase and tensin homolog
qRT-PCR	Quantitative reverse transcription PCR
RFA	Radiofrequency ablation
RFS	Recurrence-free survival
SCD1	Stearoyl-CoA desaturase 1
SMAD4	Small mothers against decapentaplegic 4
TACE	Transarterialchemoembolisation
TCGA	The Cancer Genome Atlas
TGFβR1	Transforming growth factor β receptor 1
TKIs	Tyrosine kinase inhibitors
TME	Tumor microenvironment
TNM	Tumor–node–metastasis staging
TS	Tumor-suppressor
VEGF	Vascular endothelial growth factor
VE-cadherin	Vascular endothelial cadherin
XPO1	Exportin 1 (gene symbol)
YAP1	Yes-associated protein 1