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. 2025 Aug 22;13(9):2052. doi: 10.3390/biomedicines13092052
AMD Age-related macular degeneration
VEGF Vascular endothelial growth factor
GA Geographic atrophy
PK Pharmacokinetics
IVT Intravitreal
RPE Retinal pigment epithelium
FDA United States Food and Drug Administration
TNF Tumor necrosis factor
DISC Death-inducing signaling complex
NaIO3 Sodium Iodate
RIPK Receptor-interacting protein kinase
CSE Cigarette smoke extract
USDA United States Department of Agriculture
IACUC Institutional Animal Care and Use Committee
apoB100 apolipoproteinB100
HFD High-fat diet
LC-MS/MS Liquid chromatography-mass spectrometry/mass spectrometry
TBS Tris-buffered saline
BSA Bovine serum albumin
AIF-1/IBA1 Allograft inflammatory factor 1/ionized calcium-binding adapter molecule 1
ZO-1 Zonula occludens-1
RIPA Radioimmunoprecipitation assay buffer
LLOQ Lower limit of quantification
CS Cigarette smoke
WT Wild type
RD Retinal detachment
IRD Inherited retinal degeneration
RGC Retinal ganglion cell
ILM Inner limiting membrane
EMT Epithelial–mesenchymal transition