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. 2025 Sep 5;15(9):1286. doi: 10.3390/biom15091286
AMD Age-related Macular Degeneration
AAV Adeno-Associated Virus
AAV2 Adeno-Associated Virus Serotype 2
BCs Bipolar Cells
ChR2 Channelrhodopsin-2
ChRmine Channelrhodopsin Mine
CNV Choroidal Neovascularization
FDA U.S. Food and Drug Administration
GA Geographic Atrophy
GHCR Gleobacter–Human Chimeric Rhodopsin
ILM Inner Limiting Membrane
IVT Intravitreal Injection
LED Light-Emitting Diode
MCO1/MCO-010 Multicharacteristic Opsin 1/010
MNV Macular Neovascularization
MW-opsin Medium-Wavelength Cone Opsin
ONL Outer Nuclear Layer
OPN4 Melanopsin
PPV Pars Plana Vitrectomy
PRs Photoreceptors
RGCs Retinal Ganglion Cells
Rho Rhodopsin
RPE Retinal Pigment Epithelium
RPD Reticular Pseudodrusen
SC Suprachoroidal Injection
SD-OCT Spectral Domain Optical Coherence Tomography
SDD Subretinal Drusenoid Deposits
SNAG-mGluR2 Synthetic Opsin–Metabotropic Glutamate Receptor 2 Fusion Protein
SR Subretinal Injection
VEGF Vascular Endothelial Growth Factor