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. 2025 Oct;31(10):968–981. doi: 10.18553/jmcp.2025.25199

TABLE 3.

2022 Price Benchmarks for a 30-Day Equivalent Supply for IPAY 2027 Selected Drugs

Brand name Generic name List price Part D net price Estimated rebate (%) Big Four/FSS price Non-FAMP Price based on the minimum statutory discount MFP ceiling
Products whose ceiling may be defined by the minimum discount
 Xtandi Enzalutamide $12,339 $9,470 23 $7,909 $9,533 $7,150 $7,150
 Pomalyst Pomalidomide $20,409 N/A N/A $13,536 $17,449 $13,086 $13,086
 Ibrance Palbociclib $14,426 $12,130 16 $10,193 $13,055 $9,791 $9,791
 Calquence Acalabrutinib $13,990 $13,431 4 $10,323 $12,642 $9,481 $9,481
 Austedo/Austedo XR Deutetra-benazine $6,198 $4,812 22 $4,511 $5,382 $4,037 $4,037
 Vraylar Cariprazine $1,323 $994 25 $940 $1,232 $924 $924
 Ofev Nintedanib-esylate $12,081 $10,643 12 $6,609 $12,142 $9,107 $9,107
 Xifaxan Rifaximin $2,558 $2,186 15 $1,711 $2,417 $967a $967
Products whose ceiling may be defined by the estimated Part D net price
 Trelegy Ellipta Fluticasone/Umeclidinium/Vilanterol $642 $305 53 $438 $617 $463 $305
 Breo Ellipta Fluticasone/Vilanterol $395 $158 60 $271 $374 $281 $158
 Otezla Apremilast $4,193 $2,223 47 $2,620 $3,842 $2,881 $2,223
 Linzess Linaclotide $508 $244 52 $344 $475 $357 $244
 Ozempic/Wegovy/Rybelsus Semaglutide $1,017 $428 58 $626 $880 $660 $428
Janumet/Janumet XR Sitagliptin/Metformin $503 $141 72 $361 $421 $168a $141
 Tradjenta Linagliptin $461 $194 58 $304 $420 $315 $194
a

Denotes drugs where the minimum statutory discount is 40% of the non-FAMP. All other drugs have a minimum statutory discount set by 75% of the non-FAMP.

FSS = Federal Supply Schedule; MFP = maximum fair price; N/A = not applicable; non-FAMP = non–federal average manufacturer price; XR = extended-release.