Figure 2. Flux Distributions Obtained from FBA Using the MAP Model and Objective Function c ₁ .

(A) in an unperturbed state, (B) upon deletion of inhA, (C) upon deletion of pcaA, and (D) upon inhibition of InhA. Insets in (A) and (C) refer to enlarged versions of the indicated portions. Note that the scale for (D) is different. It may be noted that the lines joining the various flux points have been drawn to aid in discerning the flux peaks clearly; the lines as such have no physical significance.