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. 2025 Sep 10;26(18):8794. doi: 10.3390/ijms26188794
ADC antibody–drug conjugate
ADCC antibody-dependent cell-mediated cytotoxic reaction
BAC bacterial artificial chromosome
bsAb bispecific antibody
BTK Bruton tyrosine kinase
CAR chimeric antigen receptor
CDC complement-dependent cytotoxicity
cDNA complementary DNA
CDR complementarity-determining region
c-erbB-2 cellular homolog of the avian erythroblastosis virus oncogene B2
cHL classical Hodgkin lymphoma
CRC colorectal cancer
CXCR7 chemokine receptor type 7
DAG diacylglycerol
dMMR deficient mismatch repair
EGFR epidermal growth factor receptor
ELISA enzyme-linked immunosorbent assay
EMA European Medicines Agency
Fab antigen-binding fragment
Fc crystallizable fragment
FcR Fc receptor
FDA Food and Drug Administration
G3P minor envelope protein
G8P major envelope protein
GEF guanine nucleotide exchange factor
HAMA human anti-mouse antibody
HC heavy chain
HER2 human epidermal growth factor receptor 2
HGF hepatocyte growth factor
HGPRT hypoxanthine–guanine phosphoribosyltransferase
HNSCC head and neck squamous cell carcinoma
IgH immunoglobulin heavy chain
IgL immunoglobulin light chain
IL-2 interleukin 2
IP3 cytosolic inositol-1,4,5 trisphosphate
ITAM immunotyrosine-based activating motif
ITIM immunotyrosine-based inhibitor motif
LC light chain
LFIA lateral flow immunoassay
mAb monoclonal antibody
MAC membrane-activating complex
MACS magnetic cell sorting system
MAPK mitogen-activated protein kinase
MCC Merkel-cell carcinoma
MEK serine–tyrosine–threonine kinase
MSI-H microsatellite instability-high
mUC metastatic urothelial carcinoma
Nbs nanobody
NSCLC non-small cell lung carcinoma
PCR polymerase chain reaction
PD-1 programmed death receptor-1
PD-L1 programmed death ligand 1
PEG polyethylene glycol
PH pleckstrin homology
PI3K phosphoinositide 3-kinase
PKC protein kinase C
PLC-γ phospho-lipase C-gamma
RAS rat sarcoma virus
RCC renal cell carcinoma
ROS reactive oxygen species
scFv single-chain Fv fragment
sdAb single-domain antibody
SFK SRC family kinase
SHIP Src homology 2 domain-containing inositol 5′-phosphatase
SHP Src homology 2 domain-containing protein tyrosine phosphatase
SYK spleen tyrosine kinase
TNF-α tumor necrosis factor-alpha
UCC urothelial carcinoma
VEGFR2 vascular endothelial growth factor receptor 2
VSIV vesicular stomatitis Indiana virus
YAC yeast artificial chromosome