| ABS | Asexual blood stages |
| ACTs | Artemisinin-based combination therapies |
| ADME | Absorption, distribution, metabolism, and excretion |
| ALA | 5-Aminolevulinic acid |
| ANT | Adenine nucleotide translocator |
| ART | Artemisinin |
| ARTs | Artemisinin and its derivatives |
| CLogP | Calculated logarithm of the partition coefficient |
| CoQ | Coenzyme Q |
| CRISPR | Clustered Regularly Interspaced Short Palindromic Repeats |
| CTT1 | Cytosolic catalase |
| CybL | Cytochrome b large |
| CybS | Cytochrome b small |
| Cyt c | Cytochrome c |
| DHA | Dihydroartemisinin |
| EC50 | Half-maximal effective concentration |
| ELQs | Endochin-like quinolones |
| Fp | Flavoprotein |
| G3PDH | Glycerol 3-phosphate dehydrogenase |
| GSK | GlaxoSmithKline |
| HTS | High-throughput screening |
| IC50 | Half-maximal inhibitory concentration |
| Ip | Iron–sulfur cluster protein |
| Ki | Inhibitory constant |
| LSs | Liver stages |
| Mdh1 | Mitochondrial malate dehydrogenase |
| mETC | Mitochondrial electron transport chain |
| MMV | Medicines for Malaria Venture |
| NaFAc | Sodium fluoroacetate |
| ND | Not detected |
| PD | Plasmodione |
| PfACO | Plasmodium falciparum aconitase |
| PfBCKDH | Plasmodium falciparum branched chain ketoacid dehydrogenase complex |
| PfCHA | Plasmodium falciparum Ca2+/H+ antiporter |
| PfCOCP | Plasmodium falciparum citrate/oxoglutarate carrier protein |
| PfDHODH | Plasmodium falciparum dihydroorotate dehydrogenase |
| PfENT1 | Plasmodium falciparum purine transporter |
| PfFH | Plasmodium falciparum fumarate hydratase |
| PfG3PDH | Plasmodium falciparum glycerol 3-phosphate dehydrogenase |
| PfIDH | Plasmodium falciparum isocitrate dehydrogenase |
| PfKDH | Plasmodium falciparum α-ketoglutarate dehydrogenase |
| PfMQO | Plasmodium falciparum malate-quinone oxidoreductase |
| PfNDH2 | Plasmodium falciparum type II NADH dehydrogenase |
| PfPiT | Plasmodium falciparum phosphate transporter |
| PfSDH | Plasmodium falciparum succinate dehydrogenase |
| PHB | Prohibitin |
| Phyre2 | Protein homology/analogY recognition engine |
| Pi | Inorganic phosphate |
| PK | Pharmacokinetic |
| PQ | Primaquine |
| RBCs | Red blood cells |
| ROS | Reactive oxygen species |
| SBS | Sexual blood stages |
| SCID | Severe combined immunodeficiency |
| SFC | Sodium ferrous citrate |
| SOD1 | Cytosolic superoxide dismutase |
| SOD2 | Mitochondrial superoxide dismutase |
| TCA | Tricarboxylic acid |
| TCPs | Target candidate profiles |
| WHO | World Health Organization |
| Δψm | Mitochondrial membrane potential |
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