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. 2025 Sep 15;15(9):613. doi: 10.3390/metabo15090613
IR Insulin resistance
LDL Low-density lipoproteins
VLDL Very-low-density lipoprotein
HDL High-density lipoprotein
LPO Lipid peroxides
ROS Reactive oxygen species
IGF-1 Serum Insulin-like Growth Factor 1
SASP Senescence-associated secretory phenotype
PIP2 Phosphatidylinositol 4,5-diphosphate
PIP3 Phosphatidylinositol (3,4,5)-trisphosphate
GLP-1 Glucagon-like peptide 1 receptor
SGLT-2 Sodium-glucose co-transporter protein
PUFAs Polyunsaturated fatty acid
O2 Oxygen
IRS2 Insulin Receptor Substrate 2
NAD+ Nicotinamide adenine dinucleotide
NAMPT Nicotinamide phosphoribosyltransferase
SCN Suprachiasmatic Nucleus
FFAs Free Fatty Acids
NADP Nicotinamide adenine dinucleotide phosphate
NO Nitric oxide
ET-1 Endothelin-1
TyG Triglyceride–glucose index
AMPK Adenosine Monophosphate-activated Protein Kinase
TP53 Tumor Protein p53
KRAS Kirsten Rat Sarcoma Viral Oncogene Homolog
O2 Superoxide Anion
H2O2 Hydrogen Peroxide
·OH Hydroxyl Radical
NO· Nitric Oxide
IL-6 Interleukin-6
TNF-α Tumor Necrosis Factor Alpha
NLRP3 NOD-, LRR- and Pyrin Domain-Containing Protein 3
IL-1β Interleukin-1 Beta
TLR4 Toll-Like Receptor 4
NF-κB Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells
LPS Lipopolysaccharide
CAR-T Chimeric Antigen Receptor T-Cell Therapy
TERT Telomerase Reverse Transcriptase
p16INK4a Cyclin-Dependent Kinase Inhibitor 2A
mTOR Mechanistic Target of Rapamycin
FMT Fecal Microbiota Transplantation
Shc Src Homology and Collagen Homology
Grb2 Growth Factor Receptor-Bound Protein 2
PI3K Phosphoinositide 3-Kinase
Ras Rat Sarcoma virus
Raf Rapidly Accelerated Fibrosarcoma
MEK Mitogen-Activated Protein Kinase Kinase
ERK1/2 Extracellular Signal-Regulated Kinase 1 and 2
GSK3β Glycogen Synthase Kinase 3 Beta
FOXO1 Forkhead box protein O1
AS160 Akt Substrate of 160 kDa
CREB CAMP Response Element-Binding protein
mTORC1 Mammalian Target Of Rapamycin Complex 1
PEPCK Phosphoenolpyruvate carboxykinase
G6Pase Glucose-6-Phosphatase
GLUT4 Glucose Transporter type 4
SREBP1c Sterol Regulatory Element-Binding Protein 1c
VCAM-1 Vascular Cell Adhesion Molecule-1
PDGF Platelet-Derived Growth Factor
ox-LDL Oxidized Low-Density Lipoprotein