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. 2025 Sep 3;18(9):1321. doi: 10.3390/ph18091321
ACLD Advanced chronic liver disease
AIH Autoimmune hepatitis
ARBs Angiotensin-II type 1 receptor blockers
ASK1 Apoptosis Signal-regulating Kinase 1
Bambi BMP and activin membrane-bound inhibitor
BDL Bile duct ligation
CCl4 Carbon tetrachloride
DAMPs Damage-associated molecular patterns
DPP Dipeptideyl peptidase 4
ECM Extracellular matrix
EZH2 Enhancer of zeste homolog 2
FFAs Free fatty acids
FGF21 Fibroblast Growth Factor 21
FIB-4 Fibrosis-4
FMT Faecal microbiome transplantation
FXR Farnesoid X receptor
GLP-1 Glucagon-like peptide 1
GLP1RA Glucagon-like peptide-1 receptor agonists
GLS1 Glutaminase 1
HBV Hepatitis B virus
HCC Hepatocellular carcinoma
HCV Hepatitis C virus
HDACs Histone deacetylases
HDV Hepatitis D virus
HK2 Hexokinase 2
HMGB1 High-mobility group box 1
HSCs Hepatic stellate cells
IFN-γ Interferon-gamma
IL-1β Interleukin-1 beta
IL-10 Inteleukin-10
ITT Intention-to-treat population
KCs Kupffer cells
KDM6B Lysine demethylase 6B
kPa Kilopascals
LDHA Lactate dehydrogenase A
lncRNAs Long non-coding RNAs
LPS Lipopolysaccharide
MALAT1 Metastasis Associated Lung Adenocarcinoma Transcript 1
MASH metabolic dysfunction-associated steatohepatitis
MASLD Metabolic dysfunction-associated steatotic liver disease
MEG3 Maternally Expressed 3
miRNAs MicroRNAs
mITT Modified intention-to-treat population
ML NASH CRN Machine Learning NASH Clinical Research Network
MRE Magnetic resonance elastography
NASH Non-alcoholic fatty liver disease
NF-κB Nuclear factor kappa B
NFS NAFLD fibrosis score
NK Natural Killer
NKT Natural Killer T
NOX NADPH oxidase
OCA Obeticholic acid
PAMPS Pathogen Associated Molecular Patterns
PBC Primary biliary cholangitis
PDGF Platelet-derived growth factor
PKM2 Pyruvate kinase M2
PNPLA3 Patatin-like phospholipase domain-containing 3
PPAR Peroxisome proliferator-activated receptor
PRRs Pattern recognition receptors
PSC Primary sclerosing cholangitis
ROS Reactive oxygen species
SAF Steatosis Activity Fibrosis
SCD1 Stearoyl-CoA desaturase
SCFAs Short-chain fatty acids
SGLT-2 Sodium–glucose cotransporter 2
SIRT1 Sirtuin 1
SUCRA Surface under the cumulative ranking curve
SWE Shear wave elastography
TCA Tricarboxylic acid
TE Transient elastography
TGFβ1 Transforming growth factor beta 1
THR Thyroid hormone receptor agonists
TLRs Toll-like receptors
TM6SF2 Transmembrane 6 superfamily member 2
TNF-α Tumor necrosis factor alpha
VLDL Very-low-density lipoproteins