| aCSF | artificially simulated cerebrospinal fluid |
| BBB | blood–brain barrier |
| CMC | critical micelle concentration |
| CT | citalopram |
| CT-PM | citalopram-loaded polymeric micelles |
| DLS | dynamic light scattering |
| EE | encapsulation efficiency |
| PF127 | Pluronic F-127 |
| FDA | food and drug administration |
| H-bonds | hydrogen bonds |
| HLB | hydrophilic–lipophilic balance |
| HPLC | high-performance liquid chromatography |
| IN | intranasal |
| IV | intravenous |
| LCST | low critical solution temperature |
| MPS | monophagocytic system |
| NCLs | nanostructured lipid carriers |
| P188 | Poloxamer 188 |
| PBS | phosphate buffer solution |
| PdI | polydispersity index |
| PEO | poly(ethylene oxide) |
| PES | polyether sulfone |
| PMs | polymeric micelles |
| PPO | poly(propylene oxide) |
| R2 | regression coefficient |
| RES | reticuloendothelial system |
| SNES | simulated nasal electrolyte solution |
| SSRIs | selective serotonin reuptake inhibitors |
| XRPD | X-ray powder diffraction |
| WHO | World Health Organization |
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