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. 2025 Sep 12;9:e81912. doi: 10.2196/81912

Table 2.

Mean weight change percentage achieved in months 1, 3, 6, and 12 by molecule.

Month Tirzepatide cohort (n=209; %), mean (SD) Semaglutide cohort (n=130; %), mean (SD)
1 −1.3 (4.1) −3.8 (14.1)
3 −7.9 (4.8) −8.1 (14.2)
6 −15.2 (5.8) −12.8 (14.6)
12 −22.1 (9.8) −17.1 (16.7)