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. 2004 Jul 21;112(15):1472–1480. doi: 10.1289/ehp.7039

Table 5.

Immature rat uterotrophic assays (6 days’ duration) using synthetic diets of different ME content (experiments 5 and 6).

Experiment/treatment Diet ME intake (kJ/g diet)a Total energy intake (kJ)b/rat Absolute uterine blotted weight (mg)c Adjusted uterine blotted weight (mg)d Final body weight (g)c No.
Experiment 5
 RM1 10.9 485 27.6 ± 3.1 31.0 57.7 ± 6.5 10
 Diet B 12.1 483 36.6 ± 6.7* 40.2** 57.5 ± 5.1 10
 AIN-76A 15.7 696 45.0 ± 12.4** 42.1** 66.4 ± 5.1** 10
 Diet C 16.2 666 44.7 ± 7.2** 42.9** 64.9 ± 5.8** 10
 Diet D 20.3 907 47.5 ± 8.3** 42.0** 70.0 ± 6.4** 10
 RM1/AO 10.9 471 30.4 ± 4.0 38.1 51.8 ± 8.2** 10
 RM1/DES 5 μg/kg 10.9 530 131.2 ± 18.0** 133.9** 60.3 ± 5.6** 4
Experiment 6
 RM1/AO 10.9 520 26.4 ± 5.3 29.3 62.3 ± 5.4 10
 Diet A/AO 8.2 426 33.2 ± 6.7 36.9* 61.0 ± 6.8 10
 Diet B/AO 12.1 555 39.7 ± 7.8** 39.8** 66.5 ± 7.0* 10
 Diet C/AO 16.2 897 50.8 ± 16.2** 49.0** 69.3 ± 5.0** 10
 Diet D/AO 20.3 1,010 55.6 ± 18.6** 51.9** 72.2 ± 5.5** 10
 Diet E/AO 22.3 481 50.9 ± 15.4** 48.0** 71.0 ± 4.1** 10
 RM1/DES 5 μg/kg 10.9 434 122.4 ± 17.2** 124.6** 60.7 ± 6.3 4
 RM1/ANT 10.9 493 16.1 ± 1.2 20.1 60.6 ± 4.6 10
 Diet A/ANT 8.2 408 17.4 ± 1.5 22.6 58.9 ± 5.6# 10
 Diet B/ANT 12.1 816 18.6 ± 2.1 21.5 62.3 ± 8.6 10
 Diet C/ANT 16.2 314 19.2 ± 1.5 14.9 72.9 ± 6.3# 10
 Diet D/ANT 20.3 991 18.4 ± 1.9 15.6 70.9 ± 5.1# 10
 Diet E/ANT 22.3 1,131 19.1 ± 2.6 14.7 73.1 ± 6.9# 10
 RM1/DES 5 μg/kg/ANT 10.9 465 153 ± 20.8# 154.5# 58.7 ± 2.7 4

DES was administered subcutaneously.

a

The ME value for RM1 was taken from the manufacturer’s data sheet.

b

Total energy intake was calculated as the product of the total amount of food consumed per rat over the duration of the study and the ME of the diet.

c

Mean ± SD.

d

Uterine weights adjusted for covariance with terminal body weights.

*p < 0.05 and

**p < 0.01 compared with RM1 or RM1/AO control.

#

p < 0.01 compared with RM1/ANT control.