TABLE 3.

Serotype-specific IgG antibody GMCs of patients previously not responding to pneumococcal polysaccharide vaccination^a

PnC	GMC (μg/ml) (95% CI)						Comparison of groups A and B
	Group A (PCV-7 primed) (n = 16)			Group B (PPV-23) (n = 17)
	Day 0	Day 7	Day 28	Day 0	Day 7	Day 28	Day 0	Day 7	Day 28
4	0.75 (0.45-1.05)	3.59** (0.00-8.25)	5.62* (1.80-9.44)	0.39 (0.17-0.61)	0.60* (0.21-0.99)	1.02 NS (0.50-1.54)	**	***	***
5	0.64 (0.54-0.75)	0.91* (0.74-1.08)	1.25* (0.92-1.58)	0.73 (0.48-0.99)	0.95 NS (0.31-1.58)	1.21 NS (0.33-2.10)	NS	NS	NS
6B	0.64 (0.00-1.44)	1.76** (0.00-3.85)	2.24 NS (0.18-4.29)	0.18 (0.02-0.33)	0.27* (0.00-0.62)	0.32 NS (0.07-0.57)	*	*	***
9V	0.82 (0.19-1.45)	2.37** (0.00-7.22)	4.28** (0.00-10.4)	0.43 (0.00-2.18)	0.83* (0.00-1.68)	0.83 NS (0.00-2.17)	NS	*	**
14	3.50 (2.50-4.49)	8.39** (0.00-18.4)	13.0* (0.00-28.7)	1.13 (0.54-1.73)	1.48* (0.86-2.11)	1.75 NS (1.38-2.12)	***	***	***
18C	0.86 (0.00-2.09)	2.35* (0.63-4.08)	2.94 NS (1.54-4.33)	0.39 (0.20-0.59)	0.78** (0.41-1.15)	1.13 NS (0.29-1.96)	NS	*	*
19F	2.30 (0.00-5.27)	7.20** (0.00-15.02)	10.59* (2.35-18.8)	0.79 (0.34-1.24)	1.67** (1.25-2.10)	2.60** (1.22-3.99)	*	***	***
23F	0.88 (0.14-1.63)	2.93** (0.00-7.22)	3.54 NS (0.25-6.83)	0.17 (0.03-0.31)	0.21* (0.00-0.62)	0.28 NS (0.00-0.88)	**	***	***

^aPnC, pneumococcal serotype; n, number of patients; NS, not significant. *, P < 0.05; **, P < 0.01; ***, P < 0.001.