Table 3.
Results of biochemical analysis in BPA, corn oil control, and MeP+PrP dose groups
| Control | MeP+PrP | p | ||||
|---|---|---|---|---|---|---|
|
|
|
|||||
| Oil control Mean±SD | BPA (50 mg/kg bw/day) Mean±SD | 10 (mg/kg bw/day) Mean±SD | 100 (mg/kg bw/day) Mean±SD | 500 (mg/kg bw/day) Mean±SD | ||
| ALT/GPT(IU/L) | 23.75±5.85 | 38.75±19.62 | 52±18.79 | 34.25±21.48 | 35±4.24 | 0.104 |
| AST/GOT(IU/L) | 21.50±6.36 | 144.50±19.09 * | 73.0±5.66 * | 19.5±0.71 | 109.50±9.19 * | 0.018 |
| AST/ALT ratio | 1.05±0.12 | 2.23±0.41 * | 2.03±0.08 * | 0.74±0.08 | 2.59±0.17 * | 0.001 |
| Albumin (g/L) | 31.75±1.34 | 29.13±0.25 * | 28.78±1.44 * | 29.27±1.40 * | 29.21±0.74 * | 0.010 |
| Creatinine (µmol/L) | 44±4.69 | 42.5±8.35 | 52±8.04 | 23±4.24 * | 37.5±9.40 | 0.001 |
| Triglyceride (mmol/L) | 0.18±0.07 | 0.25±0.07 | 0.24±0.06 | 0.35 ±0.02 * | 0.23±0.06 | 0.028 |
| Urea (mmol/L) | 2.49±0.15 | 1.98±0.43 | 2.06±0.07 * | 2.46±0.15 | 2.11±0.20 | 0.001 |
*
: Statistically different from the corn oil control group (significance level p<0.05). MeP: Methylparaben; PrP: Propylparaben; BPA: Bisphenol-A; SD: Standard deviation; ALT: Alanine aminotransferase; GPT: Glutamic pyruvic transaminase; AST: Aspartate aminotransferase; GOT: Glutamic oxaloacetic transaminase.