Table 3.
Association of SHR with all-cause death, CVD death, and MACE by ACS and CCS.
| Model 1 | Model 2 | Model 3 | ||||
|---|---|---|---|---|---|---|
| HR (95%CI) | P value | HR (95%CI) | P value | HR (95%CI) | P value | |
| All death | ||||||
| ACS | ||||||
| SHR | 2.39 (1.24 - 4.61) | 0.009 | 2.94 (1.56 - 5.52) | 0.001 | 2.09 (0.96 - 4.55) | 0.064 |
| T1 | Ref. | Ref. | Ref. | |||
| T2 | 0.67 (0.45 - 0.98) | 0.038 | 0.74 (0.51 - 1.09) | 0.124 | 0.81 (0.51 - 1.28) | 0.356 |
| T3 | 1.18 (0.84 - 1.65) | 0.344 | 1.42 (1.01 - 1.99) | 0.044 | 1.22 (0.79 - 1.86) | 0.369 |
| CCS | ||||||
| SHR | 3.32 (2.35 - 4.69) | <0.001 | 3.05 (2.16 - 4.31) | <0.001 | 2.98 (1.63 - 5.45) | <0.001 |
| T1 | Ref. | Ref. | Ref. | |||
| T2 | 0.76 (0.57 - 1.02) | 0.067 | 0.92 (0.69 - 1.24) | 0.592 | 0.99 (0.63 - 1.56) | 0.967 |
| T3 | 1.50 (1.18 - 1.92) | 0.001 | 1.66 (1.30 - 2.12) | <0.001 | 1.55 (1.04 - 2.30) | 0.031 |
| CVD death | ||||||
| ACS | ||||||
| SHR | 3.33 (1.06 - 10.44) | 0.039 | 3.58 (1.19 - 10.78) | 0.024 | 1.53 (0.34 - 6.80) | 0.577 |
| T1 | Ref. | Ref. | Ref. | |||
| T2 | 0.49 (0.21 - 1.15) | 0.103 | 0.54 (0.23 - 1.27) | 0.161 | 0.73 (0.29 - 1.80) | 0.492 |
| T3 | 1.80 (0.97 - 3.35) | 0.065 | 2.04 (1.09 - 3.80) | 0.025 | 1.47 (0.68 - 3.17) | 0.327 |
| CCS | ||||||
| SHR | 5.42 (3.05 - 9.64) | <0.001 | 4.60 (2.57 - 8.23) | <0.001 | 5.29 (1.82 - 15.38) | 0.002 |
| T1 | Ref. | Ref. | Ref. | |||
| T2 | 0.80 (0.42 - 1.52) | 0.505 | 0.97 (0.51 - 1.85) | 0.938 | 1.21 (0.43 - 3.40) | 0.722 |
| T3 | 2.25 (1.36 - 3.74) | 0.002 | 2.48 (1.49 - 4.13) | <0.001 | 2.85 (1.21 - 6.70) | 0.016 |
| MACE | ||||||
| ACS | ||||||
| SHR | 1.56 (0.97 - 2.53) | 0.069 | 1.83 (1.15 - 2.91) | 0.011 | 1.73 (0.98 - 3.04) | 0.058 |
| T1 | Ref. | Ref. | Ref. | |||
| T2 | 0.85 (0.67 - 1.06) | 0.153 | 0.92 (0.73 - 1.16) | 0.480 | 0.96 (0.73 - 1.24) | 0.740 |
| T3 | 1.11 (0.89 - 1.39) | 0.338 | 1.25 (1.00 - 1.56) | 0.053 | 1.17 (0.90 - 1.52) | 0.230 |
| CCS | ||||||
| SHR | 1.85 (1.39 - 2.45) | <0.001 | 1.78 (1.35 - 2.34) | <0.001 | 1.69 (1.10 - 2.59) | 0.017 |
| T1 | Ref. | Ref. | Ref. | |||
| T2 | 0.78 (0.65 - 0.94) | 0.008 | 0.88 (0.73 - 1.05) | 0.155 | 0.97 (0.76 - 1.25) | 0.839 |
| T3 | 1.12 (0.95 - 1.32) | 0.177 | 1.21 (1.03 - 1.43) | 0.021 | 1.23 (0.96 - 1.56) | 0.097 |
Model 1: univariate model; Model 2: adjust for age, and sex; Model 3: adjust for age, sex, BMI, SBP, smoking, drinking, TC, LDL-c, eGFR, and HR.
SHR, stress hyperglycemia ratio; CVD, cardiovascular disease; MACE, major adverse cardiovascular events; ACS, acute coronary syndrome; CCS, chronic coronary syndrome; HR,hazard ratio.