FIG. 1.

Analysis of the restriction endonuclease profile of the 438-bp amplification products of 10 reference strains of C. burnetii. (A) The amplification products were digested with SspI, electrophoresed on agarose gels, and stained with ethidium bromide. Lane 1, molecular size markers (100-bp DNA ladder); lanes 2 to 8, seven reference strains (Nine Mile VR 615, Priscilla, MAN, ME, GQ212, SQ217, and KoQ229, respectively), lanes 9 to 11, three Japanese isolates (307, 605, and TK-1, respectively); lane 12, negative control. (B) The amplification products were digested with SalI. The samples in lanes 2 to 12 are the same as those in panel A. The numbers on the right are in base pairs.