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. 2025 Sep 30;15(43):36237–36248. doi: 10.1039/d5ra03505h

Table 5. Aerobic oxidative synthesis of pyridine derivatives with CuMnFe-LDHzyme/DDQa and CuMnFe-LDHzyme/4-phenyl urazoleb catalytic system.

Entry Substrate Product DDQ 4-Phenyl urazole
Time (h) Yield (%) Time (h) Yield (%)
1 graphic file with name d5ra03505h-u23.jpg graphic file with name d5ra03505h-u24.jpg 18 98 15 98
2 graphic file with name d5ra03505h-u25.jpg graphic file with name d5ra03505h-u26.jpg 16 98 14 98
3 graphic file with name d5ra03505h-u27.jpg graphic file with name d5ra03505h-u28.jpg 16 98 14 98
4 graphic file with name d5ra03505h-u29.jpg graphic file with name d5ra03505h-u30.jpg 16 90 14.5 95
5 graphic file with name d5ra03505h-u31.jpg graphic file with name d5ra03505h-u32.jpg 20 60 19 68
6 graphic file with name d5ra03505h-u33.jpg graphic file with name d5ra03505h-u34.jpg 23 76 21 85
7 graphic file with name d5ra03505h-u35.jpg graphic file with name d5ra03505h-u36.jpg 23 80 20 90
9 graphic file with name d5ra03505h-u37.jpg graphic file with name d5ra03505h-u38.jpg 24 53 24 68
a

Reaction conditions: substrate (1 mmol), CuMnFe-LDHzyme (130 mg), DDQ (10 mol%), CH3CN (3 mL) under O2 (balloon).

b

Substrate (1 mmol), CuMnFe-LDHzyme (110 mg), 4-phenyl urazole (10 mol%), CH3CN (3 mL) under O2 (balloon).