Table 5. Aerobic oxidative synthesis of pyridine derivatives with CuMnFe-LDHzyme/DDQa and CuMnFe-LDHzyme/4-phenyl urazoleb catalytic system.
| Entry | Substrate | Product | DDQ | 4-Phenyl urazole | ||
|---|---|---|---|---|---|---|
| Time (h) | Yield (%) | Time (h) | Yield (%) | |||
| 1 |
|
|
18 | 98 | 15 | 98 |
| 2 |
|
|
16 | 98 | 14 | 98 |
| 3 |
|
|
16 | 98 | 14 | 98 |
| 4 |
|
|
16 | 90 | 14.5 | 95 |
| 5 |
|
|
20 | 60 | 19 | 68 |
| 6 |
|
|
23 | 76 | 21 | 85 |
| 7 |
|
|
23 | 80 | 20 | 90 |
| 9 |
|
|
24 | 53 | 24 | 68 |
Reaction conditions: substrate (1 mmol), CuMnFe-LDHzyme (130 mg), DDQ (10 mol%), CH3CN (3 mL) under O2 (balloon).
Substrate (1 mmol), CuMnFe-LDHzyme (110 mg), 4-phenyl urazole (10 mol%), CH3CN (3 mL) under O2 (balloon).