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. 2025 Sep 17;15:1653602. doi: 10.3389/fcimb.2025.1653602

Table 3.

Diagnostic performance of LAMP for the detection of MTBC from 349 sputum specimens compared with GeneXpert MTB/RIF.

The novel assay Genexpert Sensitivity % (95% CI) Specificity % (95% CI) OPA a % (95% CI) Cohen’s κ
Positive Negative
Positive 168 4 90.32
(85.14-94.16)
97.55
(93.84-99.33)
93.70
(90.61-96.01)
0.8740
Negative 18 159
a

OPA, overall percent agreement.