FIG. 2.
Comparison of the sequences of M. tuberculosis H37Rv and the isolates containing a partial deletion of the VNTR sequence. (a) A 54-bp-long fragment of VNTR4052 and its flanking sequence are absent from isolate 667. There are two perfect 18-bp direct repeats (bold) at the border of the deleted fragment. VNTR4052 resides in a possible coding region (Rv3611). The start and stop codons of Rv3611 are double underlined. (b) A 24-bp-long fragment is absent from VNTR0580. Two pentaguanine runs are found at the border of the deleted sequence. VNTR regions are marked by thick single underlines. Boxed nucleotides and dashes denote the first nucleotide of a VNTR copy and the deleted regions, respectively.