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. 2005 Oct;43(10):5080–5084. doi: 10.1128/JCM.43.10.5080-5084.2005

TABLE 1.

Agreement of laboratory diagnostic tests with initial clinical assessment for Lyme disease

Laboratory diagnostic test (no. tested) Initial clinical assessment for Lyme disease [no. for which test result agreed (%)]
Probablea Probable or possiblea
Initial serology (80) 32 (40) 40 (50)
Any serology (80) 21 (26) 55 (69)
Skin biopsy culture (46) 10 (22) 19 (41)
Plasma culture (79) 10 (13) 46 (58)
Any culture (82) 3 (4) 54 (66)
Any serology or any culture (82) 14 (17) 63 (77)
Skin biopsy PCR (23) 9 (39) 11 (48)
Plasma PCR (55) 27 (49) 15 (27)
Any serology, any culture, or any PCR (82) 18 (22) 67 (82)
a

Probable Lyme disease is EM or history of EM and a characteristic clinical syndrome with headache, VIIth cranial nerve palsy, or arthritis; possible Lyme disease is tick exposure, rash not typical for EM, or summertime fever without identifiable source.