TABLE 3.
Discrimination of M. caprae genotypes by MIRU typing versus IS6110 RFLP among series of isolates from outbreaks or endemic foci
| Outbreak settinga | RI no.(s)b | RFLP pattern
|
MIRU pattern
|
No. of isolates | ||
|---|---|---|---|---|---|---|
| No. of bands | No. of bands changedc | No. of MIRU loci changedc | No. of copies changedc | |||
| A | 10* | 6 | NA | NA | NA | 9 |
| 10 | 7 | 1 | 0 | 0 | 1 | |
| 10 | 7 | 1 | 0 | 0 | 1 | |
| B | 36* | 4 | NA | NA | NA | 11 |
| 35 | 4 | 0 | 0 | 0 | 4 | |
| 40 | 4 | 0 | 1 | 1 | 1 | |
| C | 30* | 2 | NA | NA | NA | 1 |
| 31 | 2 | 0 | 0 | 0 | 1 | |
| 3 | 2 | 0 | 0 | 0 | 1 | |
| 2 | 2 | 0 | 0 | 0 | 50 | |
| D | 39* | 5 | NA | NA | NA | 1 |
| 38 | 5 | 0 | 1 | 2 | 1 | |
| 41 | 3 | 4 | 2 | 2 | 1 | |
| 30, 31 | 2 | 3 | 5 | 5 | 2 | |
| E | 91, 92 (wild boar, cattle)* | 5 | NA | NA | NA | 7 |
| 87, 88 (wild boar) | 4 | 1 | 1 | 1 | 2 | |
| 93, 94, 95 (wild boar, cattle) | 4 | 5 | 3 | 4 | 4 | |
| F | 4* | 8 | NA | NA | NA | 2 |
| 5 | 8 | 1 | 0 | 0 | 1 | |
| 6 | 7 | 3 | 1 | 2 | 1 | |
| 7 | 8 | 0 | 1 | 2 | 1 | |
| Total | 103 | |||||
a
A, single outbreak (one cattle farm); B, single outbreak (two cattle farms); C, four outbreaks in neighboring communities (cattle); D, four outbreaks in the same region (cattle, range within 200 km); E, seven endemic foci (within 150-km range); and F, endemic focus in red deer (within 50-km range).
b
RI numbers refer to the isolates listed in the supplemental material. The predominant genotype in each outbreak setting (A to F) is marked with an asterisk.
c
As compared to the predominant genotype (marked with an asterisk) in each outbreak setting. NA, not applicable.