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[Preprint]. 2025 Sep 27:2025.09.25.25336638. [Version 1] doi: 10.1101/2025.09.25.25336638

Table 2. Hazard Ratios of Covariates in the Semi-Competing Risks Model.

Hazard Ratios for Hospital Readmissions with a follow-up period of 180 days after medication initiation. Hazard ratios were calculated using a semi-competing risk framework, with death as a competing risk. Hazard ratios were adjusted for age, sex, race, predicted modified Rankin Score, baseline ADRD, and days from discharge to medication initiation. CI, Confidence Intervals, ADRD, Alzheimer’s Disease and Related Dementia, mRS, Modified Rankin Score.

Covariates Readmission Mortality prior to Readmission Mortality post Readmission
Estimate 95% CI Estimate 95% CI Estimate 95% CI
Initiation Strategy 0.87 (0.52, 1.47) 0.70 (0.40, 1.21) 1.27 (0.44, 3.71)
Age 1.02 (0.99, 1.05) 1.09 (1.06, 1.13) 1.01 (0.96, 1.07)
Sex (Female) 1.07 (0.71, 1.60) 0.92 (0.58, 1.45) 0.62 (0.28, 1.37)
Race (White) 1.31 (0.77, 2.24) 1.39 (0.78, 2.48) 2.32 (0.63, 8.61)
Baseline ADRD 2.33 (0.82, 6.64) 1.79 (0.63, 5.09) 1.80 (0.35, 9.18)
Predicted mRS 0.29 (0.19, 0.45) 2.43 (1.32, 4.49) 1.38 (0.60, 3.14)
Time to Initiation 0.97 (0.96, 0.98) 0.99 (0.98, 1.00) 1.01 (0.99, 1.02)