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Journal of Behavioral Addictions logoLink to Journal of Behavioral Addictions
. 2025 Sep 30;14(3):1222–1249. doi: 10.1556/2006.2025.00072

Research priorities in gambling: Findings of a large-scale expert study

Andrea Czakó 1,2,*, Marc N Potenza 3,4,5,6,7,8, David C Hodgins 9, Shu M Yu 1, Anise M S Wu 10,11, Susana Jiménez-Murcia 12,13,14,15, Henrietta Bowden-Jones 16,17,18, Daniel King 19,20, Joël Billieux 21,22, Beáta Bőthe 23, Dan J Stein 24; Gambling Research Priority Setting Consortium, Zsolt Demetrovics 20,2,1,**; Gambling Research Priority Setting Consortium, Brett Abarbanel, Lucy Albertella, Jean-Marc Alexandre, Youssef Allami, Matteo Aloi, Laura Angioletti, Wen L Anthony, Núria Aragay, Cecilia Åslund, Marc Auriacombe, Larry O Awo, Stéphanie Baggio, Michael F Baigent, Iris M Balodis, Servane Barrault, Rafał P Bartczuk, Malcolm Battersby, Maria E Bellringer, Anne H Berman, Mónica Bernaldo-De-Quirós, Roshan Bhad, Alexander Blaszczynski, Marilisa Boffo, Céline Bonnaire, Marco Bortolato, Stephane Bouchard, Amy E Bouchard, Matthias Brand, Helen Breen, Tim B Brosowski, Matthew Browne, Tony W Buchanan, Ursula G Buchner, Gerhard Bühringer, Alessandra Buja, Natale Canale, Rene Carbonneau, Sari Castrén, Maris Catania, Gaëlle Challet-Bouju, Heather A Chapman, Emeline Chauchard, Juliet Honglei Chen, Samwook Choi, Jung-Seok Choi, Mariano Chóliz, Darren R Christensen, Jenny Cisneros Örnberg, Luke Clark, Irene Cogliati Dezza, David Columb, Olivier Corbeil, Aurélien Cornil, Pinhas Dannon, Christal N Davis, Paul Delfabbro, Jeffrey L Derevensky, Gaëtan Devos, Mike J Dixon, Maria Anna Donati, Nicki A Dowling, Magali Dufour, Simon Dymond, Enrique Echeburúa, Boris Egloff, Jennifer D Ellis, Tara Elton-Marshall, Ana Estévez, Repairer Etuk, Shirley Fecteau, Fernando Fernández-Aranda, Naomi A Fineberg, Gabriele Fischer, Mal Flack, David Forsström, Rebecca G Fortgang, Ingmar H A Franken, Fabio Frisone, Johannes Fuss, Sally M Gainsbury, Belle Gavriel-Fried, Anna M Giannini, Montserrat Gómez García, Joaquín González-Cabrera, Adam S Goodie, Alessio Gori, Anna E Goudriaan, Marie Grall-Bronnec, Roser Granero, Mark D Griffiths, Joshua B Grubbs, Tara Hahmann, Anders Håkansson, Brian J Hall, Juho Hamari, Wei Hao, Tobias Hayer, Robert M Heirene, Nerilee Hing, Niklas Hopfgartner, Tristan J Hynes, Richard J E James, Paula Jauregui, Emilien Jeannot, Andrew S Kayser, Yasser Khazaal, Hyoun S Kim, Serena King, Keiji Kobara, Komathi Kolandai, Toula Kourgiantakis, Ildikó Kovács, Shane W Kraus, Ludwig Kraus, Søren Kristiansen, Daria J Kuss, Jason Landon, Debi A LaPlante, Bernard Le Foll, David M Ledgerwood, Bonnie K Lee, Bernadeta Lelonek-Kuleta, En Li, Kalle Lind, Philip Lindner, Jakob Linnet, Suzanne Lischer, Joanne Lloyd, Helen M Lloyd, Christine Lochner, Hibai Lopez-Gonzalez, Valentina Lorenzetti, Eric R Louderback, Johanna K Loy, Amandine Luquiens, Joseph Macey, Juan M Machimbarrena, Laura Macía Guerrero, Núria Mallorquí-Bagué, Viktor Månsson, Loredana A Marchica, Emanuela Mari, Simon Marmet, Giovanni Martinotti, Flora I Matheson, Sachio Matsushita, André J McDonald, Daniel S Mcgrath, Jose Menchon, Stephanie S Merkouris, Gemma Mestre-Bach, Devin J Mills, Lorenzo Moccia, Olof Molander, Sabrina Molinaro, Pedro Morgado, Franziska Motka, Viktor Mravcik, Lucero Munguía, W Spencer Murch, Juan F Navas, Sarah E Nelson, Laura L Nicklin, Giovanna Nigro, Anders Nilsson, Xavier Noel, Lia Nower, Colin O’Gara, Jane E Oakes, Ugo Pace, Stefano Pallanti, Ståle Pallesen, Arpit Parmar, Jonathan Parke, Alberto Parrado-González, Alessia Passanisi, Raimondo M Pavarin, José C Perales, Jan Peters, Rory A Pfund, Kahlil S Philander, Fulvia Prever, Alessandro Quaglieri, Jonas Rafi, Carla J Rash, Vijay Rawat, Jérémie Richard, Neven Ricijas, Amanda Roberts, Simone N Rodda, Jim Rogers, Guyonne Rogier, Sara Rolando, Nina Romanczuk-Seiferth, Don Ross, Hans-Jürgen Rumpf, Gillian E H Russell, Alex M T Russell, Paul Sacco, Dominic Sagoe, Anne H Salonen, Eva Samuelsson, James L Sanders, John B Saunders, Michael P Schaub, Mauro Schiavella, Adriano Schimmenti, Casper Schmidt, Guillaume Sescousse, Serge Sévigny, Howard J Shaffer, Steve Sharman, Jing Shi, Steven D Shirk, Lucia Sideli, Olivier Simon, Pawel Sleczka, Ryuhei So, Rhys M G Stevens, Trevor Steward, Mythily Subramaniam, Thomas B Swanton, André Syvertsen, Nassim Tabri, Hidehiko Takahashi, Stefano Tamburin, So Kum C Tang, Éric R Thériault, Shane A Thomas, Kristine R Thomsen, Alexander Tomei, Kwok Kit Tong, Joan Trujols, Samson Tse, Kosuke Tsurumi, Catherine Tulloch, Richard Tunney, Eduardo Valenciano-Mendoza, Mark van der Maas, Thilo Van Eimeren, William Van Gordon, Ruth J Van Holst, Tim Van Timmeren, Patrizia Velotti, Cristina Vintró-Alcaraz, Rachel Volberg, Kristin M von Ranson, Kathrin Weidacker, James P Whelan, Seth Whiting, Łukasz Wieczorek, Robert Williams, Ken C Winters, Michael J A Wohl, Patrick D Worhunsky, Leon Y Xiao, Kengo Yokomitsu, Murat Yucel, Martin H Zack, Meng Xuan Zhang, Alexander Zink, Francesca Zoratto
PMCID: PMC12486284  PMID: 41026532

Abstract

Objective

While gambling is a growing public health concern, research resources are limited, and no guidance is available to prioritise research. This study aimed to identify priorities for gambling research on a global scale using a systematic, transparent, and democratic methodology to inform researchers and other stakeholders.

Methods

Leading gambling researchers were invited to list gambling-related research questions that can contribute to strengthening evidence-based policy, prevention, and effective early intervention and treatment of problem gambling. Suggestions were consolidated into research options and evaluated against six criteria (Answerability, Feasibility, Effectiveness, Impact on equity and an additional two based on the category of research options: Novelty and Relevance for description-type, Potential for burden reduction and Deliverability for intervention-related options). Stakeholders ( n = 14) assigned relative weights to each criterion, and options were ranked according to their weighted research priority scores.

Results

With input from 46.9% of eligible researchers ( n = 307) from 35 countries, 1,361 questions were consolidated into 102 options. Evaluations showed strong agreement between experts, and the top 25 priorities were identified. The results highlight the need for further knowledge about the epidemiology, etiology, and consequences of problem gambling. Top-priority topics indicate the importance of focusing on vulnerable and minority groups, youth, significant others, technological innovations, advertisements, the convergence of gaming and gambling, and co-occurring conditions. Evaluating and tailoring existing measures were prioritised more highly than new interventions, and identifying factors underlying treatment seeking, drop-out and relapse was also considered a priority.

Conclusions

This initiative successfully involved the global research community in identifying gambling research priorities. The results provide information for researchers and other stakeholders for future projects and funding.

Keywords: gambling, gambling disorder, research priorities, addictive behavior, compulsive behavior, impulsive behavior, behavioral addiction, expert study, policy, treatment, intervention, prevention

Introduction

Gambling has experienced considerable expansion in the past decades and is now a legal activity in 80% of countries ( Ukhova, Marionneau, Nikkinen, & Wardle, 2024). Gambling is generally considered a leisure activity, but it has also been recognised to have an addictive potential and negatively affect many people. Adverse consequences include financial, emotional, relational, and other harms, decreased work performance, and criminality ( Langham et al., 2015). While a minority of people who gamble experience clinically significant impairments recognised as gambling disorder ( American Psychiatric Association, 2022; World Health Organization, 2019), harms from gambling are also experienced by those who do not meet the diagnostic criteria of gambling disorder ( Browne & Rockloff, 2018) and by significant others of people who gamble ( Langham et al., 2015). Gambling also generates substantial economic burdens on societies, with the total burden approaching the levels of harm of major depressive or alcohol use disorders ( Browne et al., 2016). The international prevalence of problem gambling is 1.41% in the adult population, according to a recent meta-analysis ( Tran et al., 2024), although systematic reviews report variability in prevalence estimates related to methodological, geographical, and cultural differences ( Gjoneska et al., 2025).

Despite personal, familial, and societal harms, gambling has often been neglected as a public health issue ( Wardle, Degenhardt, Ceschia, & Saxena, 2021) and only recently started to be recognised as a serious public health concern ( Ukhova et al., 2024) that requires evidence-based strategies to tackle related harms and reduce their impact, increased levels of research and action at national and international levels ( Wardle et al., 2024). Gambling-related research has also increased in the past decades: the number of papers published in 2023 featuring the search term “gambl*” in the title or abstract in the Web of Science database was 759, more than three times higher than in 2003 ( n = 217) and eleven times higher than in 1993 ( n = 66). These manuscripts examine different aspects of gambling, including non-problematic, problematic, and disordered gambling and from different disciplinary perspectives, from genetics and neuroscience to psychological and social features, treatment, and policy issues. This rise indicates a continued need for empirical investigation towards understanding the development and maintenance of disordered gambling, how the related personal, familial, social, and economic burdens may be reduced, and how evidence-based prevention, treatment, and policy measures may be implemented.

As financial and human capacities for gambling research are limited, it is important to focus on the most pressing questions and establish priorities to properly inform stakeholders in gambling-related domains, including research communities, policymakers, and funding organisations. Nevertheless, few comprehensive initiatives have been undertaken and none have used systematic methodologies to consider gambling-related research at the international level. The consensus view of the National UK Research Network for Behavioural Addictions aimed to identify key gambling research priorities focusing solely on the United Kingdom ( Bowden-Jones et al., 2022). In an earlier initiative, a team of international experts identified knowledge gaps and created a list of future research areas as a secondary goal linked to their comprehensive framework of harmful gambling ( Abbott et al., 2018). Others applied a broader thematic focus that included gambling, such as the problematic use of the internet ( Fineberg et al., 2018) or addiction research in general ( West et al., 2019).

To fill this gap, a Research Priority Setting in Gambling Project Core Group (PCG) was created to identify research priorities (i) specifically in the gambling field, (ii) on a global level, and (iii) applying a systematic methodological approach.

Methods

The exercise adapted the Child Health and Nutrition Research Initiative (CHNRI) methodology, a transparent and democratic method developed to assist decision-making and consensus development in child health and nutrition ( Rudan, Gibson, et al., 2008), and used later in various health domains ( Rudan et al., 2017). Similar to most CHNRI exercises, the original methodology was amended to best suit the objectives.

The PCG, comprised of eight researchers from leading gambling research institutes and representing diversity in sex, geography, and research focus, defined the context, designed the methodology and conducted the project.

A comprehensive perspective was adopted when delineating the context for the research priorities, with an overarching aim to identify those gambling-related research areas that should be prioritized to strengthen existing evidence-based policy, prevention, and effective early intervention and treatment of problem gambling and gambling-related harms. The population of interest, those whose problems were aimed to be addressed, was defined on a global level and included all who have ever experienced or are at risk of experiencing any gambling-related harm, their families, affected others, communities, and societies in general. The timeframe for research priorities was the next five years.

The project was reviewed for ethical acceptability, approved by the University of Gibraltar , and preregistered on the Open Science Framework ( https://osf.io/abn3e) . It was conducted in three phases (see Fig. 1) and involved a diverse group of researchers and other stakeholders worldwide.

Fig. 1.

Fig. 1.

Overview of the research priority setting process *PCG members were excluded from the list of participants.

Phase 1 aimed to identify relevant research questions with the help of experts involved in gambling research. The inclusion criteria were being the first, last, or corresponding author of at least two gambling-related scientific papers. To identify eligible experts, a systematic database search was conducted in Web of Science using the keyword “Gambl*” within the title or abstract of papers published between 2017 and 2021. Experts were invited to complete an online survey and list 3 to 6 distinct research questions/avenues that they believed to be the most important to address in the next five years and provide information regarding their demographics, such as gender, geographical location and highest level of education, the number and types of affiliations, area of expertise, self-reported level of expertise in gambling in general and in gambling research, and scientific outputs such as publications and successful gambling-related research grants. Conflicts of interest were collected and transparently reported. Researchers contributing to all phases were invited to have group authorship provided they read, commented on and acknowledged the results and the manuscript. Phase 1 data were collected between August 2022 and February 2023.

The collected research suggestions were coded using ATLAS.ti Web ( ATLAS.ti Scientific Software Development GmbH, 2023). Irrelevant and unclear responses were removed, and duplicates, redundancies, and overlaps were combined by two authors (AC & SMY). Following the CHNRI framework that organises proposed research topics by their depth into (1) broad research domains, (2) research avenues, (3) research options, and (4) specific research questions ( Rudan, Chopra, et al., 2008), the depth of the final list was set at the level of research option corresponding to research programs for which several research projects with different methodological backgrounds could be designed to answer multiple specific research questions. To reach a uniform level, suggestions focusing on narrow, specific questions were incorporated into broader topics. The language was standardised to help the scoring, e.g., problem gambling was used as a broader term for all levels of problematic gambling, including gambling disorder, while the term gambling disorder specifically referred to the mental health disorder defined in the Diagnostic and Statistical Manual of Mental Disorders of the American Psychiatric Association (DSM-5) and the International Classification of Diseases of WHO (ICD-11).

The final list was sorted into (1) description-type research aiming to understand problem gambling, investigate prevalence, underlying causes, consequences, and burdens, (2) delivery-type research aiming to improve the delivery and accessibility of available measures and interventions, (3) development-type research aiming to evaluate or improve the effectiveness and sustainability of measures and interventions, and (4) discovery-type research aiming to innovate and develop new interventions, preventions, treatments, or policies.

For the assessment of the research options, the PCG adopted eight criteria (see Table 1). As a modification of the CHNRI methodology, two sets of six criteria were used depending on the assessed question type. The first four criteria, Answerability, Feasibility, Effectiveness, and Impact on equity, were applied to all research options, while the last two criteria varied depending on the question type. The additional two criteria for description-type research options were Novelty and Relevance, while for the intervention-focused delivery, development, and discovery-type options, these were Potential for burden reduction and Deliverability of the intervention.

Table 1.

Criteria for assessing the research options

Criterion Description Relative weight* for the assessment of description-type questions Relative weight* for the assessment of intervention-focused questions
Answerability Can a study/studies be designed to answer the research question and to achieve the proposed aims of the research? 1.05 0.91
Feasibility Are the necessary resources, conditions, and capacities available to conduct such research within the 5-year timeframe? 0.93 0.81
Effectiveness Is the research likely to lead directly or indirectly to the development or improvement of effective measures (e.g., policies, interventions, treatment) within the 5-year timeframe? 1.12 1.18
Impact on equity Does the proposed research have the potential to contribute to equity in disease burden distribution, for example, by increasing the availability of treatment and prevention for specific groups? 0.92 0.86
Novelty Is the research likely to generate novel results that significantly add to our current knowledge? 0.69 NA
Relevance Will the proposed research contribute to addressing knowledge gaps that are highly relevant to the overall understanding of problem gambling? 1.29 NA
Potential for burden reduction Does this research have the potential to contribute significantly to reducing the burden of problem gambling on people who gamble, significant others, and society? NA 1.15
Deliverability of intervention Would there be sufficient available resources (infrastructure, human capacity) and support from relevant stakeholders to successfully implement the developed measures (e.g., intervention, policy) or the improvement of these measures? NA 1.09

*The relative weights were assigned by stakeholders in Phase 3.

NA = Not applicable.

Phase 2 data were collected between May and September 2023. Phase 1 participants were invited to rate each option against six criteria considering a general, global perspective (yes (1 score), no (0 score), maybe (0.5 score), or I don't know (missing)). These ratings were averaged for each criterion and for an overall Research Priority Score (RPS).

The level of average expert agreement (AEA) was determined for each research option by dividing the number of most frequent answers by the number of responses for each criterion and calculating an average of these criteria-level agreement scores. “Maybe” answers, not representing a definite opinion, were not included in the calculation.

To include the perspectives of gambling research beneficiaries, a broader range of stakeholders, including organisations providing funding for gambling-related research, gambling regulators, and policymaking bodies were involved in Phase 3. This phase aimed to determine the relative importance of each evaluation criterion (i.e., weighted research priority scores [WRPSs]). The list of invited organisations was compiled to be geographically diverse. Stakeholders were contacted through email and asked to complete an anonymous online survey, and distributing 100 scores among the six evaluation criteria in both sets of criteria. The relative weight of each criterion was calculated by dividing the mean value of the scores by 16.7 (100/6). Weights were calculated separately for the two sets of criteria. The research options were ranked according to their WRPS values, creating two ranks (i.e., description-type and intervention-focused) for research options. Analyses were performed using IBM SPSS 27 and Microsoft Excel.

Results

Phase 1

In Phase 1, a total of 671 eligible researchers were identified. After three rounds of reminder emails, 46.9% of the invited experts completed the questionnaire ( n = 307, male = 58.6%, M age = 46.1, SD = 11.38; see Table 2). Participants were from 35 countries on 6 continents, most from Europe (54.2%) and North America (27.5%). Almost all (95.8%) were affiliated with universities or academic research institutes, and 17.6% with healthcare service provision. Most participants (86.6%) had a PhD degree. Regarding expertise, 71.3% listed psychology, 30.6% public health, 29.6% psychiatry, 22.5% neurosciences, and 20.8% epidemiology (see the full list of expertise in Table 2). The average level of self-reported expertise as a gambling researcher was 3.8 (SD = 0.87) (1 = very low to 5 = very high), while the average length for gambling-related research involvement was 12.2 years (SD = 7.11). One-third published more than 20 gambling-related peer-reviewed manuscripts, and most had been involved in gambling-related research grants as a collaborator (63.9%) or principal investigator (55.3%; see Tables 2 and 3).

Table 2.

Demographic characteristics and expertise of Phase 1 and Phase 2 respondents

Phase 1 Phase 2
n % n %
Gender n = 304 n = 263
 Male 178 58.6% 157 59.7%
 Female 126 41.4% 106 40.3%
Geographical location n = 306 n = 265
 Europe 166 54.2% 145 54.7%
 North America 84 27.5% 67 25.3%
 South America 1 0.3% 1 0.4%
 Asia 21 6.9% 21 7.9%
 Africa 4 1.3% 3 1.1%
 Oceania 30 9.8% 28 10.6%
Racial identity n = 287 n = 249
 Indigenous 1 0.3% 0 0.0%
 Black/African 4 1.4% 3 1.2%
 East Asian 22 7.7% 21 8.4%
 South Asian 6 2.1% 5 2.0%
 Hispanic 6 2.1% 5 2.0%
 Middle Eastern 3 1.0% 2 0.8%
 White/Caucasian 241 84.0% 210 84.3%
 Mixed 3 1.0% 2 0.8%
 Other 1 0.3% 1 0.4%
Highest degree of education n = 307 n = 266
 Bachelor's degree 2 0.7% 2 0.8%
 Master's degree 26 8.5% 25 9.4%
 PhD or equivalent 266 86.6% 228 85.7%
 Other 13 4.2% 11 4.1%
Number of affiliations n = 307 n = 266
 1 176 57.3% 150 56.4%
 2 94 30.6% 80 30.1%
 3 31 10.1% 30 11.3%
 4 6 2.0% 6 2.3%
Type of affiliation (multiple selection was possible) n = 306 n = 266
 Academic (university or research institute) 293 95.8% 256 96.2%
 Governmental Administration Body 6 2.0% 4 1.5%
 Company/industry 6 2.0% 5 1.9%
 Counselling, education, prevention institute/centre 1 0.3% 0 0.0%
 Health care service provider 54 17.6% 50 18.8%
 Other 10 3.3% 10 3.8%
Area of expertise (multiple selection) n = 307 n = 266
 Biology 10 3.3% 9 3.4%
 Business and Economics 11 3.6% 11 4.1%
 Computer Science and Mathematics 7 2.3% 7 2.6%
 Cultural anthropology 10 3.3% 8 3.0%
 Education Science 4 1.3% 4 1.5%
 Epidemiology 64 20.8% 56 21.1%
 Law/Legal Studies 10 3.3% 7 2.6%
 Medicine and Health 52 16.9% 46 17.3%
 Methodology 33 10.7% 29 10.9%
 Neurosciences 69 22.5% 60 22.6%
 Philosophy and humanities 5 1.6% 4 1.5%
 Political science 8 2.6% 6 2.3%
 Psychiatry 91 29.6% 80 30.1%
 Psychology 219 71.3% 193 72.6%
 Public Health 94 30.6% 81 30.5%
 Social Sciences 58 18.9% 49 18.4%
 Sociology 20 6.5% 17 6.4%
 Statistics/data science 33 10.7% 29 10.9%
 Other 18 5.9% 15 5.6%
Number of gambling related papers published n = 299 n = 260
 Less than 5 75 25.1% 64 24.6%
 Between 6 and 10 63 21.1% 56 21.5%
 Between 11 and 20 60 20.1% 52 20.0%
 More than 20 101 33.8% 88 33.8%
Number of gambling related papers published as a lead author n = 296 n = 258
 Less than 5 133 44.9% 111 43.0%
 Between 6 and 10 65 22.0% 57 22.1%
 Between 11 and 20 47 15.9% 44 17.1%
 More than 20 51 17.2% 46 17.8%
Number of successful gambling-related research grants as a principal investigator in the past 5 years n = 295 n = 255
 0 132 44.7% 111 43.5%
 1 62 21.0% 55 21.6%
 2 37 12.5% 29 11.4%
 3 16 5.4% 15 5.9%
 4 9 3.1% 7 2.7%
 5 12 4.1% 12 4.7%
 ≥6 27 9.2% 26 10.2%
Number of successful gambling-related research grants as a collaborator in the past 5 years n = 285 n = 250
 0 103 36.1% 91 36.4%
 1 59 20.7% 47 18.8%
 2 41 14.4% 37 14.8%
 3 28 9.8% 27 10.8%
 4 11 3.9% 10 4.0%
 5 7 2.5% 6 2.4%
 ≥6 36 12.6% 32 12.8%

Table 3.

Gambling-related expertise of Phase 1 and Phase 2 respondents

Phase 1 Phase 2
N Min Max Mean SD N Min Max Mean SD
Proportion of time spent with the different gambling related professional activities
 Research 304 0 100 69.7 27.37 263 0 100 70.1 27.11
 Education 304 0 70 10.8 13.21 263 0 70 10.8 13.20
 Prevention 304 0 100 4.2 9.56 263 0 50 3.9 8.04
 Clinical/treatment work 304 0 90 9.4 18.06 263 0 90 9.6 18.55
 Policy related work 304 0 35 3.5 6.73 263 0 35 3.5 6.73
 Other gambling related work 304 0 100 2.4 11.62 263 0 100 2.1 10.41
Level of expertise within the field of gambling as a whole (1 = very low, 5 = very high) 304 1 5 3.7 0.94 263 2 5 3.8 0.92
Level of expertise as a gambling researcher (1 = very low, 5 = very high) 304 1 5 3.8 0.87 263 1 5 3.9 0.85
Number of years involved in gambling research 307 1 42 12.2 7.11 266 3 42 12.2 7.14

Seventy-three participants (23.9%) confirmed having had a relationship with the gambling industry in the past five years. The nature of this relationship varied from consultancy to receiving data and research funding. Further information is provided in the conflict-of-interest statements ( Supplementary material).

The participants listed 1,361 research questions, of which 81 were excluded as being unclear or irrelevant. Based on PCG analysis and discussions, the proposals were consolidated into 102 research options: 61 (59.8%) description-type and 41 (40.2%) intervention-focused.

Phase 2

Among the 307 invited experts, 86.6% ( n = 266) participated in Phase 2 and assessed the 102 research options. Their demographic characteristics and expertise were comparable to those in Phase 1 ( Table 2). RPSs of the research options ranged from 0.585 to 0.839, while AEA levels ranged from 66.2% to 95.9% ( Appendix).

Phase 3

Representatives of 14 stakeholder organisations: eight from Europe, three from North America, and three from Australia, assessed the relative importance of the evaluation criteria. Weights assigned to the evaluation criteria are presented in Table 1.

WRPSs of the research options ranged from 0.584 to 0.848. Table 4 presents the top quarter of research options in both groups, including 15 from the description-type research options and 10 from the intervention-focused research options. AEA among these 25 options ranged from 88.7% to 95.9%.

Table 4.

The 25 highest-ranking research priorities for gambling (WRPS = Weighted Research Priority Score, AEA = average expert agreement)

Research option Type of option Theme WRPS AEA Rank within question type Overall rank
A Description-type Investigating factors related to treatment outcomes for people with gambling disorder Description Treatment 0.848 94.9% 1 1
Studying the epidemiology of problem gambling in vulnerable populations (e.g., underrepresented minority groups, individuals with mental disorders or brain injuries, low-income household members, homeless individuals) Description Epidemiology 0.845 94.8% 2 2
Epidemiological research on gambling among adolescents and young adults Description Epidemiology 0.819 91.9% 3 4
Epidemiological research on new forms of gambling Description Epidemiology 0.817 94.4% 4 5
Studying the nature and harms related to newer forms of gambling and gambling-like activities (e.g., in-play betting, fantasy sports, cryptocasinos, esports betting, virtual reality gambling) Description Consequence 0.816 95.0% 5 6
Investigating the role of gambling-focused advertising (including sponsorship, streaming platforms, online influencers) in problem gambling among youth Description Etiology 0.810 94.6% 6 7
Investigating risk and protective factors of gambling problems among adolescents and young adults Description Etiology 0.806 92.5% 7 10
Investigating the treatment needs of minority populations (ethnic, cultural, linguistic, gender, sexual, immigrant, etc.) Description Treatment 0.799 95.1% 8 11
Assessing the impact of gambling and related harms in the case of significant others (children, partners, other family members) and investigating strategies of coping Description Consequence 0.796 93.3% 9 13
Investigating the gambling behaviour and problem gambling in minority groups (ethnic, cultural, linguistic, gender, sexual, immigrant, etc.) Description Etiology 0.789 93.8% 10 15
Cross-cultural epidemiological studies of problem gambling (e.g., across time, different jurisdictions and countries with different economic conditions) Description Epidemiology 0.787 92.3% 11 17
Epidemiological research on the co-occurrence of problem gambling and non-gambling somatic, mental health and addictive disorders Description Epidemiology/comorbidity 0.784 90.0% 12 19
Reaching a scientific consensus on the definition and empirically based measures of at-risk gambling and problem gambling Description Taxonomy 0.781 88.7% 13 20
Studying the longitudinal relationship between gambling-like activities (e.g., loot boxes, social casino games), gambling engagement and problem gambling Description Etiology 0.776 89.7% 14 22
Studying the individual and environmental factors of relapse in problem gambling Description Treatment 0.773 90.6% 15 24
B Intervention-focused (delivery, development and discovery type) Investigating the effectiveness of mobile/online tools that increase the accessibility of problem gambling interventions Delivery Treatment 0.830 95.8% 1 3
Identifying factors that hinder treatment-seeking for problem gambling Delivery Treatment 0.809 95.9% 2 8
Evaluating the effectiveness of existing psychosocial treatments for gambling disorder Development Treatment 0.807 94.3% 3 9
Identifying factors behind dropping out of problem gambling treatment Delivery Treatment 0.798 95.8% 4 12
Evaluating the effectiveness of existing online and mobile gambling interventions for at-risk and problem gambling Development Prevention 0.792 93.7% 5 14
Evaluating the effectiveness of existing gambling problem prevention programs for adolescents and young adults Development Prevention 0.788 95.1% 6 16
Formulation of evidence-based recommendations for the regulation of gambling-related advertisements Discovery Policy 0.785 93.7% 7 18
Evaluating the effectiveness of existing treatments for gambling disorder co-occurring with other addictive or mental health disorders Development Treatment 0.778 93.9% 8 21
Development of evidence-based interventions to prevent relapse Discovery Prevention 0.776 91.9% 9 23
Tailoring evidence-based treatments for subgroups of people with gambling disorder (e.g., youth, adolescents, older adults, women, minorities) Development Treatment 0.773 93.5% 10 25

Description-type research option priorities

Epidemiological themes focusing on different populations and gambling forms were the most prominent, including the epidemiology of problem gambling in vulnerable populations, adolescents and youth, and epidemiological research on emerging forms of gambling and on the co-occurrence of problem gambling and other disorders (A2, A3, A4, A11, A12).

The second most prominent theme was etiological research (A6, A7, A10, A14) investigating the role of gambling-focused advertising among youth, risk and protective factors of gambling problems among adolescents and young adults, gambling in minority groups, and longitudinal relationships between gambling-like activities and gambling.

Three research options focused on treatment-related topics. Investigating factors related to treatment outcomes was ranked first (A1), with an AEA of 94.9%. Other topics included the treatment needs of minority populations (A8) and relapse in problem gambling (A15).

Two options focused on the harms and negative consequences of gambling (A5, A9): studying harms related to newer forms of gambling and gambling-like activities and harms experienced by significant others such as children, partners, and other family members and their strategies of coping. One taxonomy-themed research option suggested reaching a consensus on the definition and empirically based measures of at-risk and problem gambling (A13).

There were four options among the top fifteen according to the two group-specific criteria (i.e.: Relevance and Novelty) that were not included in the overall fifteen due to scoring relatively low on the Answerability and Feasibility criteria. These included the investigation of gambling-related policymaking and barriers to meaningful changes, establishing globally harmonised psychometric tools for cross-cultural research, assessing the social cost and public health impact of problem gambling across countries, and differentiating between harm from problem gambling and harm from co-occurring conditions (A18, A19, A22, A37).

Intervention-focused research option priorities

Five of the top ten options were development-type, three were delivery-type, and two were discovery-type. Six focused on treatment, three on prevention, and one on policy.

Treatment-themed options included investigating the effectiveness of mobile/online tools, psychosocial treatments, and treatments for gambling disorder co-occurring with other disorders, identifying factors that hinder treatment-seeking and factors behind treatment drop-out and tailoring treatments for subgroups of people such as youth, older people, women, and minorities (B1, B2, B3, B4, B8, B10).

From the three prevention-themed options, the evaluation of youth prevention programs, online and mobile interventions for at-risk gambling, and the creation of interventions to prevent relapse were the emerging topics (B5, B6, B9). The policy-themed research option suggested formulating evidence-based recommendations for the regulation of gambling advertisements (B7).

Discussion

This global priority-setting exercise identified the most pressing questions in gambling research through a well-defined process involving gambling researchers. More than half of the experts had led successful gambling related research grants as principal investigators in the past five years, and the majority has published more than five gambling related papers as a lead author.

Although the suggestions identified a wide range of topics, there was strong agreement regarding the most important research gaps. Several overlapping themes, objectives, populations, and methodological requirements emerged from the highly prioritised research options. The high proportion of descriptive research questions indicates that despite the increasing amount of gambling-related research over the past decades, there is a need to generate further fundamental knowledge about the epidemiology, risk and protective factors of problem gambling and gambling-related harms. This aligns with global research priorities set for other mental health disorders that include research on root causes, risk and protective factors ( Collins et al., 2011), and also with UK research priorities that include longitudinal research on the prevalence of disordered gambling and gambling-related harms ( Bowden-Jones et al., 2022). Although understanding the neurobiological basis of gambling disorder, which was one of the priorities set in the UK, was included in the listed research options, it did not emerge as a priority topic in this exercise.

The results highlight a need for an increased focus on vulnerable populations relating to ethnic, cultural, linguistic, gender, sexual, educational, and income factors. The prevalence of gambling problems in vulnerable groups, specific gambling-related harms and treatment needs require further exploration, especially as several of the above characteristics, including poor educational attainment and financial problems, were previously identified as risk factors for gambling disorder ( Moreira, Azeredo, & Dias, 2023). The few available studies conclude that certain minority groups appear more vulnerable to developing gambling disorder ( Okuda et al., 2016), tend to start to gamble and develop gambling problems at younger ages, and experience more negative consequences when diagnosed with gambling disorder ( Grant & Chamberlain, 2023). The lack of research investigating gambling in sexual and gender minorities has also been noted ( Gartner, Bickl, Härtl, Loy, & Häffner, 2022; Lee & Grubbs, 2023).

Multiple specific concerns involve adolescents and young people. They are at heightened risk of problem gambling, likely due to their emotional and cognitive immaturity and increased susceptibility to peer influences and advertisements ( Emond & Griffiths, 2020). According to the UK Gambling Commission report, 26% of teenagers have gambled for money within the past year, and 0.7% have experienced problem gambling ( Young People and Gambling, 2023). Future research should focus on understanding the determinants of youth gambling, how these change over time ( Calado, Alexandre, & Griffiths, 2017), and how health impacts and negative consequences might extend to adulthood ( Armitage, 2021).

Research related to significant others of those who gamble was also highlighted. Negative consequences of gambling impact close individuals ( Langham et al., 2015), including emotional, relational, and financial, health, and other harms, especially among former and present partners and family members ( Hing et al., 2022). As these harms are associated with substantial distress, exploring causalities and the development and nature of harms needs further investigation ( Tulloch, Browne, Hing, Rockloff, & Hilbrecht, 2023).

Two themes shifted the focus from those who gamble and experience gambling-related harms to the gambling industry. One was the investigation of the risks and consequences of new technological innovations, emerging forms of gambling and gambling-like activities, including gambling-like elements of video games. Features in the intersection of video games and gambling, such as loot-boxes, disproportionately affect youth, create challenges for families ( Király, Zhang, Demetrovics, & Browne, 2021), and may promote gambling harms ( Zendle & Cairns, 2018). Furthermore, emerging and rapidly changing technologies, including new devices, designs, personalised marketing strategies, and artificial intelligence, may increase the accessibility of gambling, create new risks and increase the ways people experience harm ( Swanton, Blaszczynski, Forlini, Starcevic, & Gainsbury, 2021). The other theme concerned research on gambling-focused advertising, especially in relation to youth vulnerability, and formulating evidence-based recommendations for regulations. Although research focusing on advertising increased in the past decade, the pace and range of methods and topics should be expanded ( Torrance et al., 2021).

Regarding research into prevention and treatment, the empirical evaluation of the effectiveness of existing measures was generally more highly prioritised than the creation of new interventions. This aligns with the UK research priorities, pressing the need to conduct randomised controlled trials on interventions and to investigate factors related to successful outcomes ( Bowden-Jones et al., 2022), in line with previously set global mental health research priorities ( Tomlinson, 2009). However, the range of measures to be evaluated needs to be determined, and a focus should be placed on methodologically rigorous, high-quality studies ( Brand et al., 2025).

Regarding the improvement of the accessibility and delivery of existing interventions, results highlight the importance of acknowledging the heterogeneity of people who gamble and tailoring existing preventive and treatment measures to the needs of different groups, including vulnerable groups, young people, women, and minorities. The accessibility of available treatments was also identified as an important research priority theme, including investigating the barriers to treatment-seeking and factors linked to dropping out. Despite the availability of various treatment services and self-help options, help-seeking among people with gambling problems remains low, with one-fifth or less seeking any help ( Bijker, Booth, Merkouris, Dowling, & Rodda, 2022), and four out of ten dropping out ( Pfund et al., 2021). Results suggest that individual and environmental factors related to relapse also need further exploration. Although there is a high rate of reoccurrence of gambling disorder after recovery, studies exploring predictive factors and long-term follow-up studies are scarce ( Grall-Bronnec et al., 2021).

The co-occurrence of physical and mental health disorders was another key theme, signalling a need for related epidemiological research and the evaluation of treatment effectiveness. Gambling disorder is frequently associated with co-occurring mental disorders, for example, substance use, mood, anxiety, and personality disorders ( Petry, Stinson, & Grant, 2005). However, there exists limited knowledge about the complex temporal and causal relationships between these different conditions and the underlying etiological factors ( Hartmann & Blaszczynski, 2018). Furthermore, as these comorbid mental disorders are associated with higher problem-gambling severity and poorer treatment success ( Wullinger, Bickl, Loy, Kraus, & Schwarzkopf, 2023), integrated assessment and treatment of co-occurring conditions are required ( Dowling et al., 2015).

Reaching a scientific consensus on the definition and appropriate measures of at-risk gambling and problem gambling was also considered timely. Although multiple validated tools exist to identify problem gambling ( Dowling et al., 2019), no consensus has been reached on their use and on how they should be applied in different contexts of screening, diagnosis, measurement of symptom severity or harms related to gambling ( Bowden-Jones et al., 2022).

Several research topics identified in this collaborative work would require longitudinal research designs to fully comprehend the temporal relationships between different gambling-related phenomena and cross-cultural designs to understand the role of cultural, economic, and legislative environments. Such research methods will require significant financial resources, careful planning, and collaboration from the research community.

Finally, highly relevant topics suggested by the panel that were not considered feasible and answerable need further examination, and collaborative efforts are required to find ways of exploring them. Collaborative efforts should also be supplemented by the application of open science principles in order to increase transparency, quality and replicability of research, and to ensure that results are widely available and have a meaningful impact (see Eben et al., 2023 for a discussion).

This project has limitations. While the sample of experts was balanced in terms of sex, participants from North America and Europe, and who were White, were overrepresented, although this might be representative of the characteristics of the global researcher population. There was a high percentage of psychologists and psychiatrists among the respondents, which might contribute to the predominance of the treatment perspective, as opposed to other topics such as research on policies. This also indicates that the group of researchers publishing intensively in the field is relatively homogenous in terms of academic background, and gambling research would likely benefit from having more researchers from other disciplines, such as economics, sociology, mathematics, or political science. All stakeholders participating in Phase 3 were from Australia, Europe, and North America, while other parts of the world were not represented. Also, the range of the research priority scores was relatively narrow, making it difficult to differentiate between the level of importance of the top-priority questions. Findings suggest that all top-scoring themes are highly pressing.

In conclusion, this global exercise successfully involved the gambling research community and other stakeholders in identifying research priorities. Although we used a 5-year framework to help focus on what is feasible over a short term, many of the questions that require research are complex and not quickly resolvable, thus our view is that the results of this priority setting will, in fact be relevant for a longer time frame. These results provide valuable insights for researchers, policymakers, and funding organisations. To proceed, research centres and groups should focus on these priorities and address the listed options through specific projects, and funding organisations should provide funds for their implementation. Nevertheless, in some of the more general topics, such as treatment, specific expert studies would help to reach a consensus on the most relevant sub-topics and methodological recommendations. Addressing these priorities should involve multiyear plans, collaborations, predictable funding streams and comprehensive research strategies.

Supplementary material

jba-14-1222-s001.pdf (814.1KB, pdf)

Appendix

Table A1.

Detailed scoring and ranking of all research options

Type Rank Research option Type of research option Theme Unweighted criteria scores RPSs WRPSs AEA Overall rank
Answerability Feasibility Effectiveness Impact on equity Novelty Relevance Deliverability of intervention Potential for burden reduction
A Description A1 Investigating factors related to treatment outcomes for people with gambling disorder. description treatment 0.898 0.830 0.879 0.806 0.699 0.901 0.836 0.848 94.9% 1
A2 Studying the epidemiology of problem gambling in vulnerable populations (e.g., underrepresented minority groups, individuals with mental disorders or brain injuries, low-income household members, homeless individuals). description epidemiology 0.892 0.790 0.817 0.918 0.745 0.870 0.839 0.845 94.8% 2
A3 Epidemiological research on gambling among adolescents and young adults. description epidemiology 0.930 0.878 0.823 0.777 0.609 0.824 0.807 0.819 91.9% 4
A4 Epidemiological research on new forms of gambling. description epidemiology 0.860 0.833 0.785 0.706 0.872 0.850 0.818 0.817 94.4% 5
A5 Studying the nature and harms related to newer forms of gambling and gambling-like activities (e.g., in-play betting, fantasy sports, cryptocasinos, esports betting, virtual reality gambling). description consequence 0.864 0.823 0.777 0.677 0.899 0.860 0.817 0.816 95.0% 6
A6 Investigating the role of gambling-focused advertising (including sponsorship, streaming platforms, online influencers) in problem gambling among youth. description etiology 0.807 0.765 0.817 0.782 0.787 0.871 0.805 0.810 94.6% 7
A7 Investigating risk and protective factors of gambling problems among adolescents and young adults. description etiology 0.875 0.824 0.811 0.786 0.638 0.836 0.795 0.806 92.5% 10
A8 Investigating the treatment needs of minority populations (ethnic, cultural, linguistic, gender, sexual, immigrant, etc.). description treatment 0.806 0.715 0.751 0.903 0.801 0.821 0.800 0.799 95.1% 11
A9 Assessing the impact of gambling and related harms in the case of significant others (children, partners, other family members) and investigating strategies of coping. description consequence 0.858 0.809 0.767 0.766 0.727 0.821 0.791 0.796 93.3% 13
A10 Investigating the gambling behaviour and problem gambling in minority groups (ethnic, cultural, linguistic, gender, sexual, immigrant, etc.). description etiology 0.829 0.749 0.732 0.888 0.715 0.804 0.786 0.789 93.8% 15
A11 Cross-cultural epidemiological studies of problem gambling (e.g., across time, different jurisdictions and countries with different economic conditions). description epidemiology 0.855 0.725 0.750 0.812 0.745 0.814 0.784 0.787 92.3% 17
A12 Epidemiological research on the co-occurrence of problem gambling and non-gambling somatic, mental health and addictive disorders. description epidemiology/comorbidity 0.894 0.841 0.754 0.754 0.596 0.802 0.774 0.784 90.0% 19
A13 Reaching a scientific consensus on the definition and empirically based measures of at-risk gambling and problem gambling. description taxonomy 0.819 0.820 0.805 0.723 0.633 0.821 0.770 0.781 88.7% 20
A14 Studying the longitudinal relationship between gambling-like activities (e.g., loot boxes, social casino games), gambling engagement and problem gambling. description etiology 0.852 0.749 0.757 0.656 0.776 0.838 0.771 0.776 89.7% 22
A15 Studying the individual and environmental factors of relapse in problem gambling. description treatment 0.805 0.751 0.803 0.681 0.686 0.849 0.763 0.773 90.6% 24
A16 Investigating the roles of social media (i.e., online communities, influencers) in the development of problem gambling. description etiology 0.813 0.770 0.745 0.659 0.798 0.785 0.762 0.762 91.4% 33
A17 Reaching a scientific consensus on gambling craving, its assessment and its possible inclusion in diagnostic criteria for gambling disorder. description taxonomy 0.817 0.807 0.798 0.581 0.701 0.805 0.752 0.760 87.3% 34
A18 Investigating gambling-related policymaking and regulation (barriers of meaningful changes, use of empirical evidence and the involvement of multiple and specific stakeholders in the process). description other 0.755 0.667 0.765 0.719 0.770 0.850 0.754 0.760 90.1% 35
A19 Establishing globally harmonized psychometric methodologies and tools for cross-cultural epidemiological research in gambling, problem gambling and gambling-related harms. description taxonomy 0.754 0.643 0.745 0.785 0.779 0.828 0.756 0.759 89.3% 37
A20 Characteristics, etiologies and consequences of gambling among older adults. description etiology/consequence 0.848 0.782 0.715 0.772 0.675 0.728 0.753 0.756 92.3% 39
A21 Investigating the roles of interpersonal factors (e.g., loneliness, prosocial behaviours, social support, intimate relationship quality) in problem gambling. description etiology 0.878 0.842 0.728 0.659 0.622 0.748 0.746 0.754 88.7% 41
A22 Assessing the social cost and public health impact of problem gambling across countries with different cultures and regulatory policies. description consequence 0.740 0.656 0.725 0.776 0.775 0.831 0.751 0.753 89.3% 42
A23 Investigating the roles of emotions and emotional regulation in the development and maintenance of problem gambling. description etiology 0.872 0.848 0.734 0.610 0.612 0.773 0.742 0.751 87.4% 43
A24 Establishing the diagnostic criteria of gambling disorder in the next full revision of the DSM (i.e., “DSM-6”) description taxonomy 0.893 0.871 0.781 0.635 0.498 0.734 0.735 0.750 81.1% 45
A25 Investigating the associations between online gambling and other online risky behaviours (e.g., video gaming, online sexual activities, online buying). description comorbidity 0.879 0.840 0.684 0.602 0.736 0.738 0.747 0.747 88.6% 47
A26 Investigating the association between gambling type and preference and problem severity. description etiology 0.891 0.868 0.753 0.618 0.541 0.736 0.735 0.746 84.7% 48
A27 Investigating the roles of game features and designs and gambling environment in the development of problem gambling. description etiology 0.796 0.747 0.768 0.612 0.732 0.789 0.741 0.746 88.0% 49
A28 Investigating the roles of cognitive processes (metacognition, attention deficit, cognitive bias, decision-making, altered states of consciousness while gambling) in the development of problem gambling. description etiology 0.854 0.809 0.738 0.592 0.645 0.781 0.737 0.746 87.9% 50
A29 Establishing a consensus on the definition and measurement of recovery from gambling disorder. description taxonomy 0.756 0.734 0.762 0.659 0.712 0.808 0.739 0.745 87.5% 51
A30 Investigating patterns of gambling-related problems in different subgroups (e.g., age, life stage, ethnicity, gender, gambling behaviour). description consequence 0.844 0.782 0.676 0.791 0.608 0.721 0.737 0.741 90.1% 53
A31 Investigating the moderating roles of psychological and cognitive variables between poor socioeconomic status and problem gambling. description etiology 0.786 0.763 0.674 0.774 0.674 0.755 0.738 0.740 89.6% 54
A32 Reaching a scientific consensus regarding the clear definition of gambling, and where do we draw the borders between neighbouring, gambling description taxonomy 0.793 0.808 0.725 0.585 0.630 0.809 0.725 0.735 83.7% 56
A33 Investigating the roles of sex and gender in the development of problem gambling. description etiology 0.884 0.866 0.655 0.771 0.492 0.689 0.726 0.734 84.0% 58
A34 Investigating the role of problem gambling in self-harming behaviour (suicidal and non-suicidal.) description consequence 0.769 0.709 0.742 0.665 0.704 0.781 0.728 0.734 88.6% 59
A35 Investigating the effects of co-occurrences between gambling disorder and other mental health and addictive disorders on the trajectory of gambling disorder. description comorbidity 0.803 0.701 0.710 0.638 0.677 0.794 0.721 0.728 88.8% 61
A36 Investigating factors (biological, psychological, social) responsible for co-occurrences between gambling disorder and other mental health and addictive disorders. description comorbidity 0.783 0.736 0.716 0.661 0.625 0.783 0.717 0.726 86.6% 62
A37 Studying and differentiating between harm due directly to problem gambling or to co-occurring conditions. description taxonomy 0.684 0.641 0.708 0.720 0.739 0.824 0.719 0.724 84.4% 64
A38 Exploring factors associated with the continuity and discontinuity of gambling behaviour between adolescence and adulthood, and between early and middle adulthood. description etiology 0.781 0.655 0.678 0.642 0.764 0.798 0.720 0.723 88.1% 65
A39 Understanding the processes and factors underlying spontaneous recovery from gambling disorder. description consequence 0.703 0.663 0.700 0.613 0.808 0.816 0.717 0.719 87.3% 68
A40 Investigating stigma related to gambling. description other 0.824 0.783 0.643 0.726 0.621 0.694 0.715 0.718 84.8% 69
A41 Cross-cultural research on background factors and harms related to problem gambling, including the importance of cultural and structural factors (socioeconomy, cultural norms, spirituality, cross-generational factors, etc.). description etiology/consequence 0.755 0.692 0.646 0.774 0.705 0.726 0.716 0.716 88.3% 70
A42 Studying the factors (e.g., characteristics and motivations) of choosing not to gamble. description etiology 0.817 0.790 0.674 0.543 0.720 0.732 0.713 0.715 83.5% 71
A43 Identifying core gambling disorder symptoms across different subgroups of people who gamble. description consequence 0.831 0.787 0.677 0.649 0.631 0.689 0.711 0.714 84.9% 72
A44 Investigating the roles of stress and anxiety in problem gambling. description etiology 0.875 0.871 0.702 0.573 0.467 0.689 0.696 0.709 80.2% 73
A45 Investigating the roles of childhood adversities in the development of problem gambling. description etiology 0.759 0.679 0.631 0.692 0.685 0.759 0.701 0.704 83.4% 74
A46 Investigating the roles of somatic and mental health disorders in the development of problem gambling. description etiology 0.807 0.745 0.665 0.665 0.573 0.712 0.695 0.702 85.0% 75
A47 Understanding the interrelated development and causal linkages of co-occurring gambling, mental health and addictive disorders. description comorbidity 0.715 0.607 0.705 0.631 0.684 0.782 0.687 0.694 83.9% 77
A48 Investigating similarities and differences of gambling disorder and other behavioural and substance-related addictive disorders. description other 0.833 0.795 0.653 0.543 0.562 0.721 0.685 0.694 80.8% 78
A49 Investigating characteristics, background factors and consequences of gambling-related criminal activity and violence. description consequence 0.714 0.650 0.643 0.656 0.689 0.706 0.676 0.677 83.0% 82
A50 Studying the effects of gambling on the brain or neurocognitive development of adolescents. description consequence 0.733 0.614 0.614 0.555 0.769 0.767 0.675 0.676 78.3% 83
A51 Comparing background factors that differentiate between disordered and non-disordered high-level involvement in gambling. description etiology 0.758 0.734 0.627 0.570 0.658 0.688 0.673 0.674 81.6% 84
A52 Prevalence, types and characteristics of workplace gambling and related policies and harms in different workplace cultures. description epidemiology/consequence 0.773 0.718 0.630 0.605 0.712 0.628 0.678 0.674 85.4% 85
A53 Investigating the biological and neurobiological mechanisms underlying gambling disorder. description etiology 0.754 0.674 0.628 0.525 0.646 0.762 0.665 0.672 78.3% 86
A54 Defining and identifying credible, agreed-upon measures of “responsible gambling.” description taxonomy 0.654 0.668 0.687 0.599 0.633 0.723 0.661 0.666 77.3% 89
A55 Investigating the roles of chasing (losses and wins) in problem gambling. description etiology 0.845 0.816 0.659 0.455 0.425 0.662 0.644 0.659 79.3% 90
A56 Investigating the roles of conditioning in the development of problem gambling. description etiology 0.772 0.742 0.647 0.472 0.526 0.648 0.635 0.643 75.8% 93
A57 Investigating the social representation of gambling in the general population. description other 0.770 0.729 0.553 0.550 0.593 0.600 0.633 0.633 73.4% 94
A58 Investigating the roles of personality factors in problem gambling. description etiology 0.823 0.809 0.564 0.496 0.437 0.604 0.622 0.631 72.7% 95
A59 Understanding the background factors and characteristics of non-problematic gambling. description other 0.769 0.742 0.552 0.473 0.598 0.590 0.621 0.621 71.7% 96
A60 Studying the societal harms related to low-risk gambling. description consequence 0.679 0.653 0.550 0.552 0.680 0.619 0.622 0.619 73.1% 98
A61 Investigating the genetic and epigenetic processes involved in problem gambling and its development. description etiology 0.674 0.590 0.535 0.504 0.720 0.679 0.617 0.615 70.9% 99
 B Intervention-focused (Delivery, development and discovery type) B1 Investigating the effectiveness of mobile/online tools that increase the accessibility of problem gambling interventions. delivery treatment 0.903 0.872 0.824 0.736 0.810 0.837 0.830 0.830 95.8% 3
B2 Identifying factors that hinder treatment-seeking for problem gambling. delivery treatment 0.853 0.809 0.819 0.779 0.718 0.872 0.808 0.809 95.9% 8
B3 Evaluating the effectiveness of existing psychosocial treatments for gambling disorder. development treatment 0.902 0.823 0.812 0.682 0.778 0.838 0.806 0.807 94.3% 9
B4 Identifying factors behind dropping out of problem gambling treatment. delivery treatment 0.846 0.788 0.826 0.752 0.720 0.846 0.796 0.798 95.8% 12
B5 Evaluating the effectiveness of existing online and mobile gambling interventions for at-risk and problem gambling. development prevention 0.872 0.826 0.784 0.687 0.769 0.815 0.792 0.792 93.7% 14
B6 Evaluating the effectiveness of existing gambling problem prevention programs for adolescents and young adults. development prevention 0.859 0.783 0.797 0.754 0.731 0.803 0.788 0.788 95.1% 16
B7 Formulation of evidence-based recommendations for the regulation of gambling-related advertisements. discovery policy 0.829 0.810 0.804 0.748 0.716 0.804 0.785 0.785 93.7% 18
B8 Evaluating the effectiveness of existing treatments for gambling disorder co-occurring with other addictive or mental health disorders. development treatment 0.848 0.767 0.789 0.690 0.741 0.818 0.776 0.778 93.9% 21
B9 Development of evidence based interventions to prevent relapse. discovery prevention 0.817 0.742 0.796 0.672 0.725 0.871 0.771 0.776 91.9% 23
B10 Tailoring evidence-based treatments for subgroups of people with gambling disorder (e.g., youth, adolescents, older adults, women, minorities) development treatment 0.809 0.682 0.782 0.846 0.686 0.826 0.772 0.773 93.5% 25
B11 Investigating the effectiveness of standardized treatment protocols (or deviations from them). delivery treatment 0.874 0.787 0.787 0.639 0.754 0.783 0.771 0.772 90.3% 26
B12 Studying the availability of different treatment services for people with problem gambling across countries and regions. delivery treatment 0.873 0.797 0.749 0.796 0.673 0.770 0.776 0.771 93.3% 27
B13 Evaluating the effectiveness of interventions for or including significant others of people who gamble or have gambling problems. development treatment 0.843 0.766 0.763 0.688 0.722 0.828 0.768 0.770 93.2% 28
B14 Developing new psychosocial treatments and evidence-based guidelines for the treatment of gambling disorder. discovery treatment 0.833 0.765 0.777 0.680 0.735 0.808 0.766 0.768 93.7% 29
B15 Development of easily available e-health (e.g., online, mobile, game-based, virtual reality) interventions for problem gambling. discovery prevention 0.835 0.755 0.745 0.705 0.773 0.781 0.766 0.766 92.6% 30
B16 Developing evidence-based measures to facilitate treatment-seeking at an early stage of problem gambling. delivery treatment 0.755 0.702 0.811 0.708 0.704 0.871 0.759 0.765 94.2% 31
B17 Identifying effective preventive tools for vulnerable populations (e.g., underrepresented minorities, women, individuals with mental disorder and brain injuries, low-income household members, homeless individuals) and improve existing preventive interventions. development prevention 0.769 0.689 0.776 0.876 0.649 0.818 0.763 0.762 92.0% 32
B18 Formulation of evidence-based recommendations for the regulation of the gambling industry with the aim of minimizing individual and societal harms. discovery policy 0.806 0.729 0.771 0.780 0.646 0.822 0.759 0.759 89.4% 36
B19 Evaluating the effectiveness and comparative analysis of existing gambling prevention programmes in terms of reach and effectiveness. development prevention 0.804 0.723 0.772 0.723 0.703 0.803 0.755 0.757 92.0% 38
B20 Developing new forms of treatments for patients with gambling disorder that co-occur with other addictive or mental health disorders. discovery treatment 0.825 0.728 0.738 0.705 0.717 0.812 0.754 0.756 94.1% 40
B21 Evaluating the effectiveness of existing behavioural-tracking-data-based detection methods of problematic gambling behaviour used by gambling operators. development prevention 0.810 0.710 0.790 0.686 0.702 0.786 0.747 0.751 90.3% 44
B22 Big data and artificial intelligence (e.g., machine learning) analysis of behavioural tracking data to detect indices of risky/harmful behaviour, and use of collected data to inform prevention and harm-reduction approaches. discovery prevention 0.833 0.744 0.774 0.689 0.686 0.765 0.749 0.749 90.0% 46
B23 Discovering the support needs of significant affected others and developing evidence-based targeted interventions for them. discovery treatment 0.814 0.737 0.739 0.704 0.664 0.804 0.744 0.744 92.9% 52
B24 Research on the adaptation of existing evidence-based treatments for gambling disorder to account for the modern gambling landscape and new forms of gambling. development treatment 0.788 0.733 0.764 0.653 0.717 0.767 0.737 0.740 92.1% 55
B25 Identifying factors that increase or hinder the use of voluntary responsible gambling tools/interventions. delivery prevention 0.810 0.770 0.751 0.632 0.689 0.753 0.734 0.735 89.1% 57
B26 Formulation of evidence-based recommendations for the regulation of non-traditional gambling and gambling-like activities such as loot boxes in video games. discovery policy 0.800 0.734 0.735 0.704 0.650 0.768 0.732 0.731 89.4% 60
B27 Development of youth prevention measures to reduce the risk of longer term gambling problems from new forms of gambling and gambling-like activities (such as esports and skins betting, loot boxes). discovery prevention 0.782 0.683 0.727 0.701 0.684 0.768 0.724 0.726 89.2% 63
B28 Comparing the effectiveness of different treatment approaches of problem gambling at all levels of severity. development treatment 0.775 0.644 0.763 0.629 0.674 0.799 0.714 0.720 85.8% 66
B29 Critical analysis of gambling policies of different jurisdictions (including public health approach and responsible gambling policies), their changes over time, their effectiveness, connection to prevalence of problem gambling and gambling-related harm. development policy 0.753 0.696 0.740 0.734 0.635 0.756 0.719 0.719 87.9% 67
B30 Investigating key elements of effective communication with people who gamble in the prevention of problem gambling. development prevention 0.714 0.693 0.725 0.655 0.664 0.711 0.694 0.695 88.1% 76
B31 Evaluating the effectiveness of existing pharmaceutical interventions for gambling disorder. development treatment 0.837 0.753 0.685 0.520 0.691 0.669 0.693 0.692 80.5% 79
B32 Understanding background factors of problem gambling among military personnel and veterans and tailoring preventive measures. development prevention 0.820 0.727 0.640 0.703 0.625 0.671 0.698 0.691 83.3% 80
B33 Evaluating the effectiveness and comparative analysis of responsible gambling strategies and tools used by operators and possible ways to improve these. development prevention 0.741 0.656 0.710 0.622 0.634 0.750 0.686 0.689 82.9% 81
B34 Developing methodologies to identify people with at-risk gambling across countries and operators using a standardized approach. discovery prevention 0.716 0.602 0.678 0.698 0.599 0.714 0.668 0.669 82.3% 87
B35 Development of joint internet risk prevention programmes including multiple behaviours such as online gambling, video gaming. discovery prevention 0.736 0.657 0.645 0.612 0.654 0.695 0.667 0.667 82.9% 88
B36 Constructing a system/classification scale for assessing new forms of gambling for potential burden of harm before they are released to market. discovery prevention 0.660 0.576 0.695 0.638 0.598 0.751 0.653 0.659 77.3% 91
B37 Evaluating the effectiveness of existing neuromodulation (neurofeedback, transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS)) interventions for problem gambling. development treatment 0.815 0.713 0.650 0.478 0.600 0.624 0.647 0.645 76.8% 92
B38 Developing new pharmacological interventions for gambling disorder. discovery treatment 0.748 0.614 0.601 0.488 0.600 0.658 0.618 0.620 74.1% 97
B39 Finding an effective method to calculate the maximum amount of money a specific player can lose in a given time period, to improve responsible gambling tools and their implementation. discovery policy 0.612 0.593 0.586 0.536 0.566 0.636 0.588 0.590 66.2% 100
B40 Studying the applicability of artificial intelligence to support diagnosis. discovery treatment 0.677 0.594 0.578 0.509 0.574 0.586 0.586 0.586 67.9% 101
B41 Exploring new treatment approaches for gambling disorder, such as noninvasive neuromodulation (repetitive transcranial magnetic stimulation, transcranial electrical stimulation, etc.) and deep brain stimulation. discovery treatment 0.746 0.602 0.576 0.458 0.513 0.614 0.585 0.584 68.7% 102

RPS = Research Priority Score, WRPS = Weighted Research Priority Score, AEA = average expert agreement.

Funding Statement

Funding sources: SJM was partially funded by Ministerio de Ciencia e Innovación (PDI2021-124887OB-I00), Instituto de Salud Carlos III (ISCIII) (Exp: FIS22053—Ref: DTS22/00072), European Union’s Horizon 2020 research and innovation program under Grant agreement no. 101080219 (eprObes), and cofounded by FEDER (funds/European Regional Development Fund (ERDF), a way to build Europe). CIBERObn is an initiative of ISCIII.

Footnotes

Authors' contribution: AC, MNP, DCH, SMY, AMSW, SJM, HBJ, DK, JB, BB and ZD contributed to the conceptualisation and methodology. AC, SMY and ZD contributed to the data curation, conducted the formal analysis, accessed and verified the data. AC and ZD wrote the original draft of the manuscript and administered the project. AC, MNP, DCH, SMY, AMSW, SJM, HBJ, DK, JB, BB, DJS, ZD and members of the Gambling Research Priority Setting Consortium contributed to the investigation, commented on, reviewed and edited the manuscript. Members of the Project Core Group (PCG): MNP, DCH, AMSW, SJM, HBJ, DK, JB, ZD.

Conflict of interest: The authors disclose no conflicts of interest with the contents of this manuscript. MNP has consulted for Opiant Therapeutics, Game Day Data, Boehringer Ingelheim and Idorsia Pharmaceuticals; has been involved in a patent application with Yale University and Novartis; has received research support from Mohegan Sun Casino, Children and Screens and the Connecticut Council on Problem Gambling; has participated in surveys, mailings, or telephone consultations related to drug addiction, impulse-control disorders, or other health topics; has consulted for and/or advised gambling and legal entities and non-profit organizations on issues related to impulse control, internet use and addictive disorders; has performed grant reviews for research-funding agencies; has edited journals and journal sections; has given academic lectures in grand rounds, CME events and other clinical or scientific venues; and has generated books or book chapters for publishers of mental health texts. HBJ is the National Advisor on Gambling Harms for NHS England. She is the director of the National Centre for Behavioral Addictions (UK) and Vice President of the Royal Society of Medicine. DCH received workshop honorarium from the International Center for Responsible Gaming and conference support from the Alberta Gambling Research Institute. BB receives Research Support for New Academics (NP) from the Fonds de recherche du Québec – Société et culture. She has also received Banting Postdoctoral Fellowship from the Social Sciences & Humanities Research Council (2021) and Postdoctoral Fellowship SCOUP from the Fonds de Recherche du Québec – Société et Culture (2022). She has received travel grants from the Université de Montréal, Canada - Social Sciences & Humanities Research Council (SSHRC); and from the Fonds de recherches du Québec – Société et Culture (FRQSC). DJS has received consultancy honoraria from Discovery Vitality, Johnson & Johnson, Kanna, L’Oreal, Lundbeck, Orion, Sanofi, Servier, Takeda and Vistagen. SJM received consultancy honoraria from Novo Nordisk. ZD receives research support from the University of Bristol - Bristol Hub for Gambling Harms Research and consulting fee as a consultant for the Expert Group Online Addictions of the Council of Europe International Co-operation Group on Drugs and Addictions (Pompidou Group). ZD is the editor-in-chief of the Journal of Behavioral Addictions, MNP, DK, JB, and BB serve as associate editors to the journal. The University of Gibraltar received funding from the Gibraltar Gambling Care Foundation, an independent, not-for-profit charity, and donations from gambling operators through the LCCP RET process supervised by the UK Gambling Commission. The declaration of interests of the members of the Gambling Research Priority Setting Consortium are included in Supplementary material. None of the above-listed sources are related to this study, and the funding institutions/organisations had no role in the study design, data collection, analysis, interpretation, manuscript writing, or decision to submit the paper for publication.

Contributor Information

Andrea Czakó, Email: andczako@gmail.com.

Zsolt Demetrovics, Email: zsolt.demetrovics@gmail.com.

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