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. 2025 Sep 30;25:882. doi: 10.1186/s12888-025-07217-0

Table 2.

Comparison of DNA methylation levels between groups

Patients Controls
CpG sites Max Min M SD Max Min M SD B SE z value P OR OR(95%CI)
CpG_1/3/8 0.38 0.00 0.21 0.09 0.55 0.00 0.21 0.09 −0.495 2.245 0.049 0.825 0.610 0.007 ~ 49.624
CpG_2 0.64 0.28 0.45 0.09 0.64 0.00 0.47 0.10 −2.249 2.036 1.220 0.269 0.106 0.002 ~ 5.704
CpG_4 1.00 0.07 0.76 0.25 1.00 0.22 0.81 0.21 −0.753 0.845 0.794 0.373 0.471 0.090 ~ 2.468
CpG_5 0.42 0.00 0.09 0.07 0.25 0.00 0.11 0.06 −2.876 2.949 0.951 0.329 0.056 0.000 ~ 18.235
CpG_6 0.47 0.00 0.22 0.13 0.35 0.00 0.14 0.08 7.565 1.931 15.351  < 0.001** 1928.580 43.833 ~ 84,853.465
CpG_7 0.31 0.00 0.08 0.06 0.47 0.00 0.08 0.08 −2.868 2.845 1.017 0.313 0.057 0.000 ~ 14.987
CpG_9 0.21 0.00 0.05 0.05 0.18 0.00 0.05 0.04 −1.297 4.773 0.074 0.786 0.273 0.000 ~ 3161.378
CpG_10 0.20 0.00 0.08 0.04 0.37 0.00 0.08 0.05 −2.694 4.045 0.444 0.505 0.068 0.000 ~ 187.491
CpG_11 0.33 0.00 0.07 0.07 0.89 0.00 0.07 0.11 −0.216 1.948 0.012 0.912 0.806 0.018 ~ 36.662
CpG_12 0.92 0.00 0.10 0.15 0.56 0.00 0.09 0.11 0.485 1.465 0.110 0.740 1.625 0.092 ~ 28.678

CpG Cytosine-phosphate-Guanine, Max maximum, Min minimum, M mean, SD standard deviation, B regression coefficient, SE Standard Error, z value, Wald Z-Score, OR Odds Ratio, OR (95% CI), Odds Ratio with 95% Confidence Interval

P, P-value; *P < 0.05, **P < 0.01