Table 2.
The morbidity and mortality burden of hepatoblastoma among the 21 GBD regions, percentage change and estimated annual percent change between 1990 and 2021
| Incidence | Deaths | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Number | ASR | Number | ASR | |||||||||
| 1990 | 2021 | PC | 1990 | 2021 | EAPC | 1990 | 2021 | PC | 1990 | 2021 | EAPC | |
| Africa | ||||||||||||
| North and Middle East |
494.49 (363.20, 626.77) |
329.21 (258.26, 418.23) |
−33.43 (−52.17, 8.36) |
0.10 (0.07, 0.12) |
0.05 (0.04, 0.07) |
−1.47 (−1.62, −1.33) |
345.12 (253.95, 439.81) |
207.81 (163.13, 264.61) |
−39.78 (−56.73, −2.33) |
0.07 (0.05, 0.09) |
0.03 (0.03, 0.04) |
−1.82 (−1.94, −1.69) |
| Central Sub-Saharan |
149.69 (80.52, 236.45) |
96.54 (43.07, 177.06) |
−35.50 (−68.31, 67.84) |
0.15 (0.08, 0.23) |
0.05 (0.02, 0.08) |
−3.73 (−3.92, −3.53) |
106.51 (57.59, 169.19) |
67.95 (30.54, 128.14) |
−36.20 (−68.81, 65.85) |
0.10 (0.06, 0.17) |
0.03 (0.01, 0.06) |
−3.77 (−3.97, −3.57) |
| Southern Sub-Saharan |
32.96 (21.31, 44.96) |
39.65 (27.76, 53.36) |
20.32 (−22.38, 97.24) |
0.04 (0.03, 0.06) |
0.05 (0.03, 0.07) |
0.12 (−0.17, 0.41) |
23.09 (14.89, 31.96) |
27.78 (19.73, 37.25) |
20.35 (−22.74, 97.80) |
0.03 (0.02, 0.04) |
0.03 (0.02, 0.05) |
0.11 (−0.19, 0.41) |
| Western Sub-Saharan |
728.20 (528.23, 958.65) |
823.63 (590.15, 1092.90) |
13.11 (−17.72, 54.54) |
0.20 (0.14, 0.26) |
0.10 (0.07, 0.14) |
−2.13 (−2.25, −2.01) |
512.58 (372.73, 672.85) |
570.57 (412.61, 754.29) |
11.31 (−18.83, 51.85) |
0.14 (0.10, 0.18) |
0.07 (0.05, 0.09) |
−2.19 (−2.31, −2.06) |
| Eastern Sub-Saharan |
570.58 (389.58, 750.81) |
509.77 (296.93, 887.71) |
−10.66 (−49.19, 83.09) |
0.16 (0.11, 0.21) |
0.08 (0.05, 0.14) |
−2.08 (−2.19, −1.97) |
403.16 (275.32, 530.64) |
356.09 (208.91, 622.67) |
−11.67 (−49.56, 81.55) |
0.11 (0.08, 0.15) |
0.06 (0.03, 0.10) |
−2.12 (−2.23, −2.01) |
| America | ||||||||||||
| Caribbean |
11.54 (7.37, 16.70) |
7.09 (4.67, 11.03) |
−38.55 (−57.90, −8.87) |
0.03 (0.02, 0.04) |
0.02 (0.01, 0.03) |
−1.23 (−1.45, −1.01) |
8.04 (5.10, 11.68) |
4.79 (3.13, 7.50) |
−40.45 (−59.43, −11.22) |
0.02 (0.01, 0.03) |
0.01 (0.01, 0.02) |
−1.34 (−1.57, −1.11) |
| Southern Latin America |
3.49 (3.00, 4.03) |
3.86 (3.15, 4.63) |
10.57 (−14.73, 42.22) |
0.01 (0.01, 0.01) |
0.01 (0.01, 0.01) |
1.47 (1.20, 1.75) |
2.35 (2.02, 2.72) |
2.14 (1.76, 2.58) |
−8.86 (−29.44, 17.48) |
0.00 (0.00, 0.01) |
0.00 (0.00, 0.01) |
0.69 (0.42, 0.96) |
| Andean Latin America |
39.48 (28.35, 51.85) |
15.54 (10.45, 22.40) |
−60.62 (−76.25, −30.42) |
0.07 (0.05, 0.10) |
0.03 (0.02, 0.04) |
−3.52 (−3.80, −3.23) |
27.72 (19.96, 36.48) |
9.92 (6.85, 14.44) |
−64.22 (−78.28, −38.00) |
0.05 (0.04, 0.07) |
0.02 (0.01, 0.02) |
−3.84 (−4.10, −3.58) |
| Tropical Latin America |
78.10 (67.55, 92.00) |
39.92 (30.90, 48.91) |
−48.88 (−61.65, −34.99) |
0.05 (0.04, 0.05) |
0.02 (0.02, 0.03) |
−1.72 (−2.05, −1.38) |
54.33 (47.04, 64.17) |
25.65 (19.81, 31.37) |
−52.79 (−64.50, −39.98) |
0.03 (0.03, 0.04) |
0.02 (0.01, 0.02) |
−1.94 (−2.29, −1.59) |
| High-income North America |
109.95 (107.09, 112.97) |
179.17 (159.52, 200.12) |
62.95 (44.76, 81.67) |
0.05 (0.05, 0.05) |
0.09 (0.08, 0.10) |
2.10 (1.83, 2.36) |
37.60 (36.71, 38.49) |
44.73 (40.18, 49.66) |
18.95 (6.09, 31.97) |
0.02 (0.02, 0.02) |
0.02 (0.02, 0.02) |
1.04 (0.91, 1.17) |
| Central Latin America |
174.99 (162.17, 191.07) |
86.24 (66.40, 112.87) |
−50.72 (−62.46, −33.64) |
0.08 (0.07, 0.08) |
0.04 (0.03, 0.06) |
−1.54 (−1.69, −1.39) |
122.06 (113.18, 133.02) |
54.97 (42.52, 71.12) |
−54.96 (−65.42, −40.58) |
0.05 (0.05, 0.06) |
0.03 (0.02, 0.04) |
−1.84 (−1.99, −1.70) |
| Asia | ||||||||||||
| East Asia |
2315.21 (1923.65, 2834.26) |
565.79 (401.57, 801.91) |
−75.56 (−83.05, −64.71) |
0.20 (0.17, 0.25) |
0.08 (0.05, 0.11) |
−3.84 (−4.30, −3.38) |
1600.79 (1334.50, 1955.01) |
221.61 (160.34, 309.45) |
−86.16 (−90.39, −79.85) |
0.14 (0.12, 0.17) |
0.03 (0.02, 0.04) |
−5.87 (−6.42, −5.32) |
| Southeast Asia |
649.44 (434.90, 832.71) |
252.42 (185.72, 346.57) |
−61.13 (−71.27, −45.05) |
0.11 (0.07, 0.14) |
0.04 (0.03, 0.06) |
−2.85 (−3.00, −2.70) |
452.62 (303.40, 581.36) |
163.83 (121.81, 226.13) |
−63.81 (−73.08, −48.75) |
0.08 (0.05, 0.10) |
0.03 (0.02, 0.04) |
−3.10 (−3.23, −2.97) |
| Central Asia |
114.69 (93.85, 143.67) |
42.42 (31.03, 56.76) |
−63.01 (−74.19, −48.45) |
0.12 (0.10, 0.15) |
0.04 (0.03, 0.06) |
−3.31 (−3.47, −3.15) |
79.13 (64.84, 99.36) |
28.04 (20.52, 37.26) |
−64.56 (−75.29, −50.80) |
0.08 (0.07, 0.11) |
0.03 (0.02, 0.04) |
−3.49 (−3.63, −3.35) |
| High-income Asia Pacific |
100.06 (83.56, 118.87) |
37.63 (33.08, 44.48) |
−62.39 (−69.91, −52.29) |
0.10 (0.08, 0.11) |
0.06 (0.05 ,0.07) |
−1.82 (−2.56, −1.07) |
47.07 (36.27, 59.14) |
8.55 (7.62, 9.92) |
−81.84 (−86.19, −75.23) |
0.04 (0.03, 0.06) |
0.01 (0.01, 0.02) |
−4.30 (−4.72, −3.88) |
| South Asia |
1177.67 (706.70, 1587.70) |
815.54 (632.69, 1044.53) |
−30.75 (−52.66, 27.01) |
0.08 (0.04, 0.10) |
0.05 (0.04, 0.07) |
−1.04 (−1.15, −0.93) |
833.92 (496.45, 1122.17) |
559.48 (436.13, 716.62) |
−32.91 (−54.23, 22.85) |
0.05 (0.03, 0.07) |
0.04 (0.03, 0.05) |
−1.16 (−1.26, −1.06) |
| Europe | ||||||||||||
| Eastern Europe |
155.17 (144.97, 165.69) |
57.70 (52.12, 63.11) |
−62.81 (−66.19, −59.40) |
0.09 (0.09, 0.10) |
0.06 (0.05, 0.06) |
−2.12 (−2.63, −1.60) |
99.09 (93.00, 105.62) |
25.95 (23.63, 28.27) |
−73.81 (−76.12, −71.46) |
0.06 (0.05, 0.06) |
0.02 (0.02, 0.03) |
−3.50 (−3.86, −3.13) |
| Central Europe |
43.14 (37.20, 50.15) |
8.92 (7.19, 11.04) |
−79.33 (−84.37, −73.01) |
0.05 (0.04, 0.05) |
0.02 (0.01, 0.02) |
−3.56 (−4.00, −3.11) |
28.08 (24.22, 32.74) |
3.52 (2.85, 4.32) |
−87.48 (−90.41, −83.72) |
0.03 (0.03, 0.04) |
0.01 (0.01, 0.01) |
−5.36 (−5.75, −4.98) |
| Western Europe |
105.71 (100.82, 110.75) |
120.09 (104.65, 136.48) |
13.60 (−1.86, 30.48) |
0.05 (0.04, 0.05) |
0.06 (0.05, 0.07) |
0.82(0.64,0.99) |
40.91 (39.01, 42.92) |
26.94 (23.83, 30.28) |
−34.16 (−42.25, −25.28) |
0.02 (0.02, 0.02) |
0.01 (0.01, 0.01) |
−0.81 (−1.02, −0.60) |
| Oceania | ||||||||||||
| Oceania |
2.95 (1.81, 4.87) |
4.03 (2.31, 7.07) |
36.88 (−31.07, 177.07) |
0.03 (0.02, 0.05) |
0.02 (0.01, 0.04) |
−1.26 (−1.60, −0.92) |
2.06 (1.28, 3.56) |
2.78 (1.58, 4.85) |
34.99 (−32.34, 171.80) |
0.02 (0.01, 0.04) |
0.01 (0.01, 0.02) |
−1.30 (−1.64, −0.96) |
| Australasia |
6.22 (5.52, 6.94) |
13.27 (10.41, 16.63) |
113.44 (62.18, 182.36) |
0.04 (0.04, 0.05) |
0.07 (0.06, 0.09) |
2.04 (1.73, 2.35) |
2.05 (1.82, 2.29) |
3.08 (2.46, 3.79) |
49.90 (16.30, 94.17) |
0.01 (0.01, 0.01) |
0.02 (0.01, 0.02) |
1.00 (0.76, 1.23) |
DALYs: disability-adjusted life years, PC: percentage change, ASR: age-standardized rate, EAPC: estimated annual percentage change