Table 1. We compare the time-to-first event (HR) studies with the win ratio.

Hazard Ratio	Win Ratio
Simple, reproducible.	Less experience, lack of familiarity.
Requires proportional hazards.	Does not require proportional hazards (uses pairs of comparisons).
Ignores occurrence of fatal events after non-fatal events.	Incorporates all fatal events of interest.
Does not consider the hierarchy of events.	Allows establishing a hierarchy of events and analyzing other patient-focused outcomes.
Estimates sample size and statistical power.	No estimate of sample size and statistical power.
Distinguishes between short-term and long-term events.	With a single “metric” it combines short- and long-term efficacy.