Table 1.

NMR-derived constraints

Total interproton	1,384
Intraresidue	150
Sequential (i − j = 1)	330
Short range (1 < i − j < 5)	249
Long range (i − j > 4)	655
Hydrogen bonds	58
Total dihedral angles	251
φ	90
ϕ	94
χ1	67
Total coupling constants (3JHNHα)	84
Total number of constraints	1,835
Total number of constraints per residue	16.4