| AML |
Acute myeloid leukemia |
| ANT |
Adenine nucleotide translocase |
| Apaf-1 |
Apoptotic protease activating factor-1 |
| AQP4 |
Aquaporin-4 |
| ARE |
Antioxidant response element |
| ARF1 |
ADP-ribosylation factor 1 |
| ATP |
Adenosine triphosphate |
| α-KGDH |
α-Ketoglutarate dehydrogenase |
| BAK1 |
BCL2 antagonist/killer 1 |
| BAX |
BCL2-associated X protein |
| BBB |
Blood-brain barrier |
| BCL-XL |
B-cell lymphoma-extra large |
| BM MSCs |
Bone marrow mesenchymal stem cells |
| βCaMKII |
Calcium/calmodulin-dependent protein kinase II beta |
| cADPR |
Cyclic ADP-ribose |
| cGAMP |
Cyclic GMP-AMP |
| cGAS |
Cyclic GMP-AMP synthase |
| CHR |
Chrysin |
| CI/RI |
Cerebral ischemia/reperfusion |
| CL |
Cardiolipin |
| CNS |
Central nervous system |
| CS |
Citrate synthase |
| Cyp D |
Cyclophilin D |
| Cyt c
|
Cytochrome c
|
| CsA |
Cyclosporine A |
| DAMPs |
Damage-associated molecular patterns |
| DRP1 |
Dynamin-related protein 1 |
| dsDNA |
Double-stranded DNA |
| DX |
Dengzhan xixin injection |
| ECAR |
Extracellular acidification rate |
| EGFR |
Epidermal growth factor receptor |
| EPCs |
Endothelial progenitor cells |
| ER |
Endoplasmic reticulum |
| ERK |
Extracellular signal-regulated kinase |
| ETC |
Electron transport chain |
| EVs |
Extracellular vesicles |
| FABP5 |
Fatty acid-binding protein 5 |
| FABP7 |
Fatty acid-binding protein 7 |
| Fis1 |
Fission protein 1 |
| GeB |
Garcinia-derived xanthone |
| GFAP |
Glial fibrillary acidic protein |
| GTP |
Guanosine triphosphate |
| Golgi |
Golgi apparatus |
| GSDMD |
Gasdermin D |
| GSDME |
Gasdermin E |
| GSH |
glutathione |
| GSH-Px |
Glutathione peroxidase |
| GSSG |
Glutathione disulfide |
| HO-1 |
Heme oxygenase-1 |
| hNSCs |
Human neural stem cells |
| hUC-MSCs |
Human umbilical cord mesenchymal stem cells |
| H2O2
|
hydrogen peroxide |
| IMM |
Inner mitochondrial membrane |
| IKK |
IκB kinase |
| IL-1β |
Interleukin-1 beta |
| IL-6 |
Interleukin-6 |
| IMS |
Intermembrane space |
| IRAKs |
Interleukin-1 receptor-associated kinases |
| IRF3 |
Interferon regulatory factor 3 |
| ISCs |
Iron-sulfur clusters |
| LC3 |
Microtubule-associated protein 1A/1B light chain 3 |
| LC3-I |
Cytosolic LC3 |
| LC3-II |
LC3-phosphatidylethanolamine conjugate |
| LRP1 |
Lipoprotein receptor-related protein 1 |
| MAPK |
Mitogen-activated protein kinase |
| MBP |
Myelin basic protein |
| MCAO |
Middle cerebral artery occlusion |
| MDA |
Malondialdehyde |
| MFN1 |
Mitofusin 1 |
| MFN2 |
Mitofusin 2 |
| Miro1 |
Mitochondrial Rho GTPase 1 |
| MMPs |
Matrix metalloproteinases |
| mPTP |
Mitochondrial permeability transition pore |
| MQC |
Mitochondrial quality control |
| mTOR |
Mechanistic target of rapamycin |
| MSCs |
Mesenchymal stem cells |
| mtDNA |
Mitochondrial DNA |
| NAC |
N-acetylcysteine |
| N2a |
Neuro-2a |
| NF-κB |
Nuclear factor kappa-light-chain-enhancer of activated B cells |
| NLRP3 |
NLR family pyrin domain containing 3 |
| NMDA |
N-Methyl-d-aspartate |
| NO |
Nitric oxide |
| NOX2 |
NADPH oxidase 2 |
| Nrf2 |
Nuclear factor erythroid 2-related factor 2 |
| NVU |
Neurovascular unit |
| O-GlcNAcylation |
O-linked β-N-acetylglucosaminylation |
| OCR |
Oxygen consumption rate |
| OGD |
Oxygen-glucose deprivation |
| OGD/R |
Oxygen-glucose deprivation/reoxygenation |
| OMM |
Outer mitochondrial membrane |
| OPA1 |
Optic atrophy 1 |
| OPCs |
Oligodendrocyte progenitor cells |
| OXPHOS |
Oxidative phosphorylation |
| ox-mtDNA |
Oxidized mitochondrial DNA |
| OX |
xanthine oxidase |
| P2X7 |
P2X purinoceptor 7 |
| Parkin |
Parkin RBR E3 ubiquitin-protein ligase |
| PDH |
Pyruvate dehydrogenase |
| PGC-1α |
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha |
| PI3K |
Phosphoinositide 3-kinase |
| PINK1 |
PTEN-induced putative kinase 1 |
| PPAR |
Peroxisome proliferator-activated receptor |
| PRRs |
Pattern recognition receptors |
| RalA |
RAS-like protein A |
| RHOT1 |
Rho GTPase 1 |
| ROS |
Reactive oxygen species |
| RyR |
Ryanodine receptor |
| S100A4 |
S100 calcium-binding protein A4 |
| SIRT-1 |
Sirtuin 1 |
| SLC35B4 |
Solute carrier family 35 member B4 |
| STING |
Stimulator of interferon genes |
| SOD |
Superoxide dismutase |
| TBK1 |
TANK-binding kinase 1 |
| TCA cycle |
Tricarboxylic acid cycle |
| TFAM |
Mitochondrial transcription factor A |
| TLRs |
Toll-like receptors |
| TNF-α |
Tumor necrosis factor-alpha |
| TOM20 |
Translocase of the outer mitochondrial membrane 20 |
| TOM40 |
Translocase of the outer mitochondrial membrane 40 |
| TRAF6 |
TNF receptor-associated factor 6 |
| TRAK1/2 |
Trafficking kinesin proteins 1 and 2 |
| VDACs |
Voltage-dependent anion channels |
| VEGF |
Vascular endothelial growth factor |
| Wnt5a |
Wingless-type mmtv integration site family, member 5a |
| XDH |
xanthine dehydrogenase |
| ΔΨm |
Mitochondrial membrane potential |
| •OH |
highly oxidizing hydroxyl radical |
| O2•-
|
superoxide anion |