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Effect of Y-27632 on the shape of nonpolarized IAR-2 epitheliocytes. An untreated group of two epitheliocytes (A) began to extend multiple processes from their edges after 40 min of treatment with 50 μM Y-27632 (B). After 120 min of exposure to Y-27632, cells acquired highly polarized shapes with wide lamellas and multiple narrow processes (C and D). (Bar = 10 μm.)
