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. 2025 Oct 3;11(40):eadt5419. doi: 10.1126/sciadv.adt5419

Table 2. Nonoutbreak data sources considered as possible predictors for R0.

Predictor Notes Source
Biotic
 Vector species* Species: A. aegypti or A. albopictus (112, 113)
 CHIKV lineage* Lineages: Asian, ECSA, or IOL (21)
Included in all models due to observed posterior differences in R0
Climatic
 Temperature Time points: Annual mean, monthly means 0 to 3 months before outbreak (114)
Extracted from TerraClimate using longitude and latitude
 Relative humidity Time points: Annual mean, monthly means 0 to 3 months before outbreak (114)
Extracted from TerraClimate using longitude and latitude
 Precipitation Time points: Annual mean, monthly means 0 to 3 months before outbreak (114)
Extracted from TerraClimate using longitude and latitude
Eco- and Epidemiological
 Aedes occurrence probability Long-term monthly means derived from environmental data and mosquito presence-absence data (21)
Time points: Long-term annual mean, long-term monthly means 0 to 3 months before outbreak
Extracted using longitude and latitude
 Relative R0 Model of temperature effects on Aedes-borne viral transmission (29)
Time points: Annual mean, monthly means 0 to 3 months before outbreak
Computed using vector species and temperature data
 Index-P Model of temperature and humidity effects on Aedes-borne viral transmission (26)
Time points: Annual mean, monthly means 0 to 3 months before outbreak
 Dengue virus FOI Single value derived from dengue incidence and environmental data (23)
Extracted using longitude and latitude
Demographic/other
 Population density Log transformed (95, 97)
 Mean household size* (95, 97)
 Mean distance to nearest neighbor Computed by CHIKSIM population submodel This study
 Subnational human development index Combines measurements of education, health, and standard of living (64, 115, 116)
 World Health Organization region Regions: Africa, Americas, and Europe/Mediterranean (combined because of the small sample size), South East Asia, and Western Pacific
Included in all models due to observed posterior differences in R0
*

These predictors’ values were extracted from the publications documenting each outbreak, whenever possible; otherwise, we used the sources listed in the table.