Table 2.
Comparison of behavioral parameters in the open field test between negative emotion model mice and control mice.
| Parameters | Control (Mean ± SEM) | Restraint stress (Mean ± SEM) | LPS injection (Mean ± SEM) | P-value (ANOVA) |
|---|---|---|---|---|
| Displacement (pixels) | 36931±4096 | 8215±654 | 8932±930 | ∗∗∗ |
| Movement time (s) | 209.8±17.2 | 73.2±10.8 | 61.8±9.1 | ∗∗∗ |
| Velocity (pixels/s) | 123.1±12.7 | 31.4±3.7 | 25.3±1.9 | ∗∗ |
| Center residence time (s) | 80.1±9.0 | 4.7±0.7 | 3.2±1.2 | ∗∗∗ |
| Corner residence time (s) | 109.7±12.2 | 156.6±17.8 | 163.8±22.7 | ∗∗ |
| Edge residence time (s) | 110.2±10.5 | 138.7±10.0 | 133.0±8.2 | ∗ |