Fig. 1.
Integrative Signaling by Estrogen through Receptors (ER) at the Membrane and Nucleus in Breast Cancer IGF1R, IGF-I receptor; JNK, c-Jun N-terminal kinase; RSK, ribosomal S6 kinase; ERE, estrogen response element; CBP, cAMP response element binding protein (CREB)-binding protein; SRF, serum response factor.