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. 2025 Oct 3;22:156. doi: 10.1186/s12954-025-01315-8

Table 1.

Participant characteristics by nicotine use status

Variable Never users (N = 6748) Exclusive E-cigarette users (N = 520) Exclusive cigarette users (N = 1732) All (N = 9000) χ2, P-Value
Age group, n (%) χ2 = 167.12, p < 0.001
16–24 581 (8.6) 26 (5.0) 135 (7.8) 742 (8.2)
25–34 854 (12.7) 81 (15.6) 297 (17.2) 1232 (13.7)
35–44 983 (14.6) 94 (18.1) 289 (16.7) 1366 (15.2)
45–54 1149 (17.0) 123 (23.7) 359 (20.7) 1631 (18.1)
55–64 1216 (18.0) 113 (21.7) 327 (18.9) 1656 (18.4)
65–74 1129 (16.7) 73 (14.0) 220 (12.7) 1422 (15.8)
75+ 836 (12.4) 10 (1.9) 105 (6.1) 951 (10.6)
Sex, n (%) χ2 = 20.91, p < 0.001
Male 2748 (40.7) 235 (45.2) 805 (46.5) 3788 (42.1)
Female 4000 (59.3) 285 (54.8) 927 (53.5) 5212 (57.9)
Deprivation, n (%) χ2 = 613.44, p < 0.001
Most Deprived 840 (12.5) 122 (23.4) 543 (31.4) 1505 (16.7)
2 1198 (17.8) 147 (28.2) 437 (25.2) 1782 (19.8)
3 1387 (20.5) 109 (21.0) 338 (19.5) 1834 (20.4)
4 1629 (24.1) 71 (13.7) 239 (13.8) 1939 (21.5)
Least Deprived 1694 (25.1) 71 (13.7) 175 (10.1) 1940 (21.6)
Has longstanding illness, n (%) χ2 = 88.49, p < 0.001
Yes 3026 (44.8) 267 (51.3) 992 (57.3) 4285 (47.6)
No 3722 (55.2) 253 (48.7) 740 (42.7) 4715 (52.4)
Doctor diagnosed COPD, n (%) χ2 = 350.97, p < 0.001
Yes 90 (1.3) 28 (5.4) 177 (10.2) 295 (3.3)
No 6658 (98.7) 492 (94.6) 1555 (89.8) 8705 (96.7)
Doctor diagnosed Asthma, n (%) χ2 = 21.23, p < 0.001
Yes 1027 (15.2) 64 (12.3) 332 (19.2) 1423 (15.8)
No 5721 (84.8) 456 (87.7) 1400 (80.8) 7577 (84.2)
Self-rated general health, n (%) χ2 = 402.19, p < 0.001
Very good / good 5174 (76.7) 341 (65.6) 957 (55.2) 6472 (71.9)
Fair 1181 (17.5) 119 (22.9) 462 (26.7) 1762 (19.6)
Bad / very bad 393 (5.8) 60 (11.5) 313 (18.1) 766 (8.5)
Alcohol consumption in the last 12 months, n (%) χ2 = 7.74, p = 0.102
Almost daily to weekly drinking 3307 (49.0) 257 (49.4) 833 (48.2) 4397 (48.9)
Monthly or occasional 2204 (32.7) 177 (34.1) 537 (31.1) 2918 (32.5)
Non-drinker 1237 (18.3) 86 (16.5) 359 (20.7) 1676 (18.6)
Age of smoking initiation, n (%) Fisher exact p < 0.001
Early starters (≤ 16 years) 0 (0.00) 277 (53.2) 1032 (59.6) 1309 (14.5)
Late starters (> 16 years) 0 (0.00) 189 (36.4) 686 (39.6) 875 (9.7)
Missing/Not applicable 6748 (100.0) 54 (10.4) 14 (0.8) 6816 (75.7)
Second-hand smoke, n (%) χ2 = 716.66, p < 0.001
Not exposed 5333 (79.0) 347 (66.7) 812 (46.9) 6492 (72.1)
Exposed 1415 (21.0) 173 (33.3) 920 (53.1) 2508 (27.9)
Has wheezing in the last 12 months, n (%) χ2 = 455.87, p < 0.001
Yes 769 (11.4) 91 (17.5) 560 (32.3) 1420 (15.8)
No 5979 (88.6) 429 (82.5) 1172 (67.7) 7580 (84.2)