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. 2025 Sep 22;16:1655598. doi: 10.3389/fendo.2025.1655598

Figure 2.

Four bar charts labeled A to D compare various characteristics among groups labeled by the presence of TPOAb and TGAb antibodies. Each chart measures percentage distribution by different criteria. Chart A categorizes by vision levels; Chart B by an unspecified grading scale; Chart C by motion limitation types; Chart D by another unspecified grading scale. Bars are annotated with statistical significance stars.

The comparison results of the four groups of patients with TED, based on TPOAb and TGAb. (A) Comparison results of visual acuity among the four groups. The number of patients with visual acuity ≥ 1 was the lowest in the TPOAb (-) and TGAb (+) group; (B) Comparison results of orbital pressure among the four groups. The proportion of patients with orbital pressure of ++ was the highest in the TPOAb (-) and TGAb (+) group; (C) Comparison results of soft tissue involvement among the four groups. The proportion of patients with fixed eyeballs or fixed eyeball clusters was the highest in the TPOAb (-) and TGAb (+) group; (D) Comparison results of NOSPECS classification among the four groups. The proportion of patients with NOSPECS classification of 6 or above was the highest in the TPOAb (-) and TGAb (+) group. The x-axis represents each group. The y-axis represents the percentage of the different groups’ population within each group. P values were showed as: *p < 0.05; **p < 0.01; ***p < 0.001. TED, thyroid eye disease. TPOAb, thyroid peroxidase antibody. TGAb, thyroglobulin antibody.