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. 2025 Sep 22;15:1653566. doi: 10.3389/fcimb.2025.1653566

Table 2.

Significance comparison of pathological change in liver and serum HBV DNA clearance rate between Non-MASLD and MASLD group.

Non-MASLD
226
MASLD
177
P-value
Liver Pathological Feature
Necroinfammation, n (%) 0.015
 non-significant 109 (48.23%) 64 (36.16%)
 significant 117 (51.77%) 113 (63.84%)
Fibrosis, n (%)
 non-significant 164 (72.57%) 108 (61.02%) 0.014
 significant 62 (27.43%) 69 (38.98%)
Damage†, n (%) 0.050
 non-significant 93 (43.15%) 56 (31.64%)
 significant 133 (58.85%) 121 (68.36%)
Serum HBV DNA Clearance
HBV DNA negative, n (%) 0.002
 Yes 135 (59.73%) 132 (74.58%)
 No 91 (40.27%) 45 (25.42%)

MASLD, metabolic dysfunction-associated steatotic liver disease.

† Liver damage (Necroinfammation and/or Fibrosis).