Table 3.
Univariate and multivariable logistic regression analyses for identifying predictors of significant HBV DNA clearance.
| Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P-value | OR | 95% CI | P-value | |
| Age | 1.069 | (1.043,1.096) | <0.0001 | 1.043 | (1.003,1.085) | 0.03638 |
| Male | 1.418 | (0.934,2.152) | 0.10102 | |||
| BMI | 1.104 | (1.027,1.187) | 0.00701 | 0.855 | (0.746,0.981) | 0.02567 |
| MASLD | 1.977 | (1.286,3.040) | 0.00190 | 2.209 | (1.018,4.797) | 0.04505 |
| HBV DNA | 0.400 | (0.340,0.470) | <0.0001 | 0.524 | (0.410,0.669) | <0.0001 |
| HBeAg positive | 0.029 | (0.016,0.055) | <0.0001 | 0.184 | (0.069,0.492) | 0.00074 |
| PLT | 0.995 | (0.991,0.998) | 0.00304 | 0.999 | (0.991,0.998) | 0.00304 |
| TBL | 1.001 | (0.965,1.039) | 0.96389 | |||
| ALT | 1.021 | (0.996,1.046) | 0.10407 | |||
| GGT | 1.020 | (1.003,1.036) | 0.01727 | 1.005 | (0.984,1.027) | 0.62060 |
| Triglycerides | 1.057 | (0.842,1.328) | 0.63137 | |||
| HDL | 0.615 | (0.323,1.170) | 0.13864 | |||
| Cholesterol | 0.749 | (0.609,0.920) | 0.00595 | 0.665 | (0.480,0.922) | 0.01424 |
| Damage | 2.191 | (1.432,3.351) | 0.00030 | 3.134 | (1.496,6.567) | 0.00248 |
ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; GGT, gamma-glutamyl transferase; HBV DNA, Hepatitis B virus-deoxyribonucleic acid; HBeAg, hepatitis B e antigen; HDL, high-density lipoprotein; MASLD, metabolic dysfunction-associated steatotic liver disease; PLT, platelet; TBL, total bilirubin.