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. 2025 Sep 22;12:1651294. doi: 10.3389/fvets.2025.1651294

Table 2.

Virulence-related genes regulated by sRNA12.

Gene name Start site End site Free energy (kcal/mol) Gene function
sseG 311 344 −23.22 Type III secretion system effectors located on SPI-2
bapA 217 262 −22.9 Non-fimbrial adhesin, produced by the type I secretion system, is involved in biofilm formation, bacterial invasion, and adhesion
rho 193 244 −22.77 Transcription termination factor, which can regulate virulence genes
fimW 475 549 −20.61 A member of the type I fimbrial gene cluster, which regulates bacterial adhesion
ompC 726 754 −19.76 Outer membrane protein, which has good immunogenicity
sseC 60 157 −19.15 Type III secretion system translocation protein located on SPI-2
ompD 315 386 −18.93 Outer membrane protein, which has immunogenicity and regulates bacterial adhesion
siiE 1809 1835 −18.82 Non-fimbrial adhesin, encoded by SPI-4, regulates adhesion and invasion
prgH 607 673 −18.63 An important component of the type III secretion system, which promotes the delivery of virulence factors
sseJ 1,059 1,205 −18.57 Type III secretion system effectors of SPI-2