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LD50 of chicks infected with wild-type and ΔsRNA12 deletion strains.
| Group | Dose (CFU) | Number of samples | Number of deaths | Mortality rate | LD50(CFU) |
|---|---|---|---|---|---|
| W1 | 2 × 108 | 10 | 0/10 | 0% | 2.11 × 1010 |
| W2 | 2 × 109 | 10 | 1/10 | 10% | |
| W3 | 2 × 1010 | 10 | 5/10 | 50% | |
| Δ1 | 2 × 108 | 10 | 0/10 | 0% | 7.08 × 109 |
| Δ2 | 2 × 109 | 10 | 2/10 | 20% | |
| Δ3 | 2 × 1010 | 10 | 8/10 | 80% | |
| PBS | - | 10 | 0/10 | 0% | - |
