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Glucose disposal rates assessed by the hyperinsulinemic–euglycemic clamp technique. Transgenic (n = 4) and control (n = 5) male mice were infused with maximally active insulin concentrations and their glucose disposal rates determined (P < 0.01, control vs. transgenic). Weights of the mice in the two groups were equivalent (control 24.6 ± 2.1 g, transgenic 25.4 ± 3.0 g).
