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. 2002 Jul 29;99(16):10736–10741. doi: 10.1073/pnas.112338099

Fig 4.

Fig 4.

Pathways and gene families regulated by PR8 virus infection. (A) Relative mRNA levels of suppressor of cytokine gene family and associated genes during PR8, WSN, and NS 1918 virus infections. Colors represent relative change in mRNA levels relative to mock-infected cells. See legend for Fig. 3 for details on color scheme. Genes whose expression was up-regulated by PR8 virus but down-regulated by 1918 NS virus (and also by wt WSN virus, although to a lesser extent) are with solid arrow. (B) Relative mRNA levels of TRIM proteins and their corresponding chromosomal locations. Hierarchical clustering of 19 TRIM genes was performed (Fig. 12), and the cluster representing induced genes is shown. EST_810133 was identified as a TRIM gene by a blast search of the human genome. Chromosomal locations were obtained from the LocusLink database (38).