Table 1.
Literature discussing the concern for a relationship between ocular and adnexal disease and the development of secondary choroidal osteoma
| Primary disease | Age at diagnosis, years | Sex | Affected eye | Interval before onset, years | Fundus exam before diagnosis | Associate choroidal neovascularization | Reference |
|---|---|---|---|---|---|---|---|
| Branch retinal vein occlusion | 62 | M | OS | 8 | yes | yes | Adhi et al. [17], 2013 |
| CSCR | 48 | M | OS | unknown | no | no | Erol et al. [18], 2015 |
| Stargardt disease | 16 | F | OS | unknown | no | yes | Figueira et al. [19], 2007 |
| Retinitis pigmentosa | 35 | F | OD | unknown | no | no | Browning [20], 2003 |
| Behcet disease | 36 | F | OU | 2 | yes | no | Casaroli-Marano et al. [21], 2010 |
| Vogt-Koyanagi-Harada disease | 30 | F | OU | 10 | yes | no | Ozawa et al. [22], 2019 |
| Posterior scleritis | 14 | F | OU | 1 | no | no | Ng et al. [23], 2022 |
| Posterior scleritis | 17 | F | OS | 5 | yes | no | Trimble and Schatz [24], 1983 |
| Posterior scleritis | 26 | M | OS | 10 | yes | no | Sun et al. [25], 2024 |
| Pposterior scleritis (IgG4 related) | 12 | M | OD | 3 | yes | no | Nair et al. [26], 2020 |
| Orbital multifocal fibrosclerosis (IgG4 related) | 23 | F | OU | 4 | yes | no | Takkar et al. [27], 2018 |
| Orbital inflammatory pseudotumor | 11 | F | OD | 1 | yes | yes | Katz and Gass [28], 1983 |
| Langerhans cell histiocytosis (histiocytosis X) | 11 | M | OU | 11 | no | no | Kline et al. [29], 1982 |
| Langerhans cell histiocytosis | 24 | M | OU | 22 | no | no | Azadi et al. [30], 2019 |
| CSCR (case 1) | 49 | M | OS | 8 | yes | yes | Current paper |
| CSCR (case 2) | 65 | F | OS | 15 | yes | no | Current paper |
| Vogt-Koyanagi-Harada disease (case 3) | 40 | F | OU | 16 | yes | yes | Current paper, Mukai et al. [6], 2024 |
| Posterior scleritis (case 4) | 55 | M | OS | 21 | no | yes | Current paper |