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. 2025 Oct 8;25:785. doi: 10.1186/s12887-025-06060-2

Table 3.

Factors associated with cognitive development

Regression coefficients for cognitive scores (95% CI) (N = 2,494) P-value
Gestational age at birth
Term (≥ 37 weeks) Ref Ref
Preterm (< 37 weeks) −1.44 (−2.62, −0.27) 0.016
Child vaccination status
Unvaccinated −6.02 (−9.36, −2.67) < 0.001
Partially vaccinated −1.17 (−2.12, −0.22) 0.016
Fully vaccinated Ref Ref
Child nutritional status
WHZ at 6 months
Normal Ref Ref
Moderate to severe wasting (WHZ < − 2SD) −1.69 (−3.01, −0.36) 0.012
HAZ at 18 months
Normal Ref Ref
Moderate to severe stunting (HAZ < − 2SD) −2.19 (−2.91, −1.48) < 0.001
Maternal education
No education −3.87 (−5.84, −1.9) < 0.001
1–6 years −3.46 (−5.32, −1.6) < 0.001
7–10 years −2.12 (−3.94, −0.3) 0.022
≥ 11 years Ref Ref
Maternal BMI at Enrollment
Underweight (BMI < 18.5 kg/m2) −0.89 (−1.88, 0.11) 0.081
Normal weight (BMI 18.5–24.9 kg/m2) Ref Ref
Overweight (BMI 25.0–29.9 kg/m2) 0.75 (−0.2, 1.69) 0.12
Obesity (BMI ≥ 30 kg/m2) 1.75 (0.55, 2.96) 0.004
Household Hunger
No or little hunger Ref Ref
Moderate to severe hunger −1.64 (−2.81, −0.47) 0.006
Child home environment measured by the HOME-Inventory at 24 months
Organization of physical and temporal environment 0.47 (0.23, 0.71) < 0.001
Provision of appropriate play materials 0.86 (0.49, 1.23) < 0.001
Cleanliness of the child 1.23 (0.6, 1.86) < 0.001

CI Confidence Interval, WHZ Weight-for-Height Z-score, HAZ Height-for-Age Z-score, BMI Body Mass Index