Table 2.
Key clinical differences between septic arthritis and adult-onset Still's disease (AOSD) in the context of postoperative fever—emphasizing diagnostic pitfalls and distinguishing features
| Clinical features | Septic arthritis | AOSD |
|---|---|---|
| Fever | Most cases are mild and only 30%–40% of individuals have a temperature > 39℃ | Peak fever and the highest temperatures (> 39 ℃) occurs at night |
| Arthralgia and arthritis | Most cases are monoarticular and only 10%−20% of individuals have a polyarticular disease | Most cases are polyarthritis |
| Dermatologic manifestations | Erythema around the affected joint | A macular or maculopapular evanescent salmon-pink skin rash appears together with the fever spikes |
| Pharyngalgia | Generally, not present, but can occur when accompanied by throat infections | It occurs before or during the first month of each disease flare |
| Others | Occur rarely but shivering can occur | It is common and includes myalgia, enlargement of the lymph nodes, splenomegaly, hepatomegaly, pleurisy, pericarditis, weight loss, etc |