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Effects of tetracyclines on survival of scrapie-infected Syrian hamsters. (A) Survival time of hamsters injected intracerebrally with a 10−5 dilution of 263K scrapie-infected brain homogenate (shaded area) or the same inoculum after incubation with doxycycline (white area). (B) Survival time of hamsters injected intracerebrally with a 10−6 dilution of 263K scrapie-infected brain homogenate (shaded area) or with the same inoculum after incubation with tetracycline (white area).
