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. 2025 Oct 7;25:942. doi: 10.1186/s12888-025-07150-2

Table 3.

Assessment of psychiatric symptoms and psychological experience of initial infection, and proportion of psychiatric history

Author(s) and year Outcome for psychiatric symptoms during acute COVID Assessment of psychiatric symptoms in the acute phase of COVID Outcome for psychological experience of infection Proportion of psychiatric and/or addictive histories among long covid patients
1 Subramanian et al., 2022 [35] Not researched Not researched Not researched

Depression: 13.4%

Anxiety: 13.5%

Smoking (never smoked 6.8%, ex-smoker 8.9%, current smoker 8.3%)

Eating disorder: 14.5%

Substance use disorder: 12%

Learning disabilities: 9%

2 Wang and al., 2022 [36] Not researched Not researched

Declarative: Verry worried and somewhat worried about Covid-19

Perceived Stress Scale (PSS-4)

Probable depression: yes (53.4%), subclinical symptoms (48.1%)

Probable anxiety: yes (53%), subclinical symptoms (46.5%)

Smoking: active (48.4%), former (46.3%)

3 Grisanti and al., 2022 [37] Not researched Not researched Not researched Smoker (10%), ex-smoker (55%)
4 Garjani and al., 2022 [38] Not researched Not researched Not researched

Anxiety and/or depression (long-standing COVID-19 symptoms for ≥ 4 weeks): 50.4%

Anxiety and/or depression (long-standing COVID-19 symptoms for ≥ 12 weeks): 54.3%

5 Craparo and al., 2022 [39] Not researched Not researched Impact of Event Scale-Revised (IES-R) Not researched
6 Tene and al., 2022 [40] Not researched Not researched Not researched Smoking: 25.1%
7 De Oliveira and al., 2022 [41] Not researched Not researched Not researched

Smoking: 19%

Alcoholism: 8,9%

8 Ohira and al., 2022 [42] Not researched Not researched Not researched

Depression: 10%

Schizophrenia: 2,2%

Asperger's spectrum syndrom: 2,2%

9 Bai and al., 2022 [43] Not researched Not researched Not researched Active smokers (38,8%), ex-smokers (4,2%)
10 Daitch and al., 2022 [44] Not researched Not researched Not researched Not specified in long covid subjects
11 Afroze and al., 2022 [45] Not researched Not researched Not researched Not specified in long covid subjects
12 Vásconez-González and al., 2023 [46] Not researched Not researched Not researched Not specified in long covid subjects
13 Frontera and al., 2022 [47] Not researched Not researched Not researched Not specified in long covid subjects
14 Shukla and al., 2023 [48] Not researched Not researched Not researched Not specified in long covid subjects
15 Jacobs and al., 2023 [49] Not researched Not researched Not researched

Depression and anxiety: 13,7%

Cigarette smoking occasionally or regularly: 52.5%

16 Knight and al., 2022 [50] Not researched Not researched Declarative: negative psychological impact (yes/no) Not researched
17 Sansone and al., 2022 [51] Not researched Not researched Not researched

Smokers (26.3%), Ex smokers (21.9%)

Depression: 10.9%

18 Yavuz and al., 2022 [52] Not researched Not researched Not researched

Depression: 22.8%

Smoking: 18%

19 Gutiérrez-Canales and al., 2022 [53] Not researched Not researched Not researched Smoking: 20.5%
20 Hastie and al., 2022 [54] Not researched Not researched Not researched Not specified in long covid subjects
21 Fleischer and al., 2022 [55] Not researched Not researched Not researched

Previous psychiatric condition: 19%

(Depression: 66.7%

Anxiety disorder: 20.1%

Post-traumatic stress disorder: 3.3%

Somatic disorder: 3.3%

Adjustment disorder: 3.3%

Borderline disorder: 3.3%)

22 Margalit and al., 2022 [56] Not researched Not researched Not researched

Smoking status: past (24.2%), current (16.7%)

Use of cannabis: 7.7%

Use of alcohol: 48.5%; Alcohol servings per week: 1,1 (mean)

23 Gasnier and al., 2022 [57] Not researched Not researched Not researched Past psychiatric disorder: 3,95%
24 Loosen and al., 2022 [58] Not researched Not researched Not researched Not specified in long covid subjects
25 Buonsenso and al., 2022 [59] Not researched Not researched Not researched

Smoke (yes): 23.3%

Alcohol (yes): 67.7%

26 Lhuillier and al., 2022 [60] Not researched Not researched Not researched Depressive Symptoms Mean (SD): 4.23 (4.71) in Post-Acute COVID-19 Sequelae (vs 3.06 in no post acute covid sequelae)
27 Tleyjeh and al., 2022 [61] Not researched Not researched Not researched Not specified in long covid subject
28 Kidwai and al., 2022 [62] Not researched Not researched Not researched Not specified in long covid subject
29 Magdy and al., 2021 [63] Not researched Not researched Not researched

Depression: 26.7%

Smoking: 17.8%

Drug abuse: 2.2%

30 Abdelhafiz and al., 2022 [64] Not researched Not researched Not researched Smoking: 7.78%
31 Ghoshal and al., 2021 [65] Not researched Not researched Not researched Addiction (tabac, alcool): 20%
32 Peter and al., 2022 [66] Not researched Not researched Not researched Not specified in long covid subject
33 Alkwai and al., 2022 [67] Not researched Not researched Not researched

Anxiety: 13%

Depression: 7.4%

Other mental health disorder: 3.7%

34 Colizzi and al., 2022 [68] Mental health symptoms: symptoms of psychiatric disorders (depression, anxiety, insomnia), lack of concentration and focus, and fatigue Declarative Not researched Not researched
35 Martinez and al., 2021 [69] Not researched Non recherché Not researched History of depression or state of exhaustion: 5%
36 Uygur and al., 2021 [70] Not researched Not researched Not researched Fatigue group: History of psychiatric disease (24.5%); History of psychiatric drug use (31%)