TABLE 6.

In-vitro Characterization of optimized MRP-spanlastics.

Independent variables (studied factors)	Optimized values
Span: Edge Activator Ratio (mol%)	1:4 mol%
Drug Concentration (mg/mL)	5 mg/mL
Edge Activator Type	Brij 35

Responses	Obtained Results
Mean particle size (PS, nm)	462 nm
Polydispersity index (PDI)	0.5
Zeta potential (ZP, mV)	−7.4 mV
Encapsulation efficiency (EE, %)	69%
In-vitro drug release (%)	20% after 6 h
Surface Morphology (SEM)	Spherical