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. 2025 Oct 8;15:35151. doi: 10.1038/s41598-025-19135-y

Table 3.

Multivariable logistic regression analysis of profiles categories of CRF level in different groups.

Variables B S. E Wald P OR 95%CI
C1 VS C2
PA–Index − 0.072 0.034 4.453 0.035 0.930 0.870-0.995
HHI − 0.435 0.081 29.040 0.000 0.647 0.552-0.758
GSES − 0.134 0.050 7.175 0.007 0.874 0.793-0.965
ISI 0.261 0.045 33.104 0.000 1.299 1.188–1.419
BMI − 0.224 0.093 5.811 0.016 0.799 0.666-0.959
Child–Pugh
Child-B/C
Child-A −1.763 0.643 7.521 0.006 0.172 0.049-0.605
C1 VS C3
PA–Index − 0.085 0.019 20.278 0.000 0.918 0.885-0.953
ISI 0.192 0.033 34.516 0.000 1.212 1.136–1.292
Child–Pugh
Child-B/C
Child-A −1.171 0.488 5.749 0.017 0.310 0.119-0.808
Marital status
Without spouse
Married 1.643 0.556 8.733 0.003 5.171 1.739–15.377
Economic burden
Commonly
Heavier 0.079 0.389 0.042 0.838 1.083 0.505-2.322
Very serious 0.944 0.385 6.019 0.014 2.570 1.209–5.463

C1 = Physical balance - Low fatigue, C2 = Physical prominent -High fatigue, C3 = Physical imbalance - Low fatigue.

C1 was the reference group.

Child-Pugh, Grading criteria for the quantitative evaluation of liver reserve function in patients with liver cancer are commonly used in clinics. Grades A, B, and C indicated liver damage of varying severity (the higher the score, the worse the liver reserve function).

CRF, Cancer-related fatigue; HHI, Herth Hope Index; ISI, The Insomnia Severity Index; GSES, General self-efficacy; BMI, Body-mass index(kg/m2); ref., reference group; PNI, Prognostic Nutrition Index = serum albumin (g/L) + 5× lymphocyte count (×109/L).