Table 2.
Cohort 1: effect of population density on high-grade glioma characteristics and treatment
| Variable | Total (%) N = 1925 |
Frontier (%) N = 60 |
Rural (%) N = 363 |
Urban (%) N = 1502 |
P-value |
|---|---|---|---|---|---|
| Diagnosis | .004 a | ||||
| Glioma malignant, NOS | 202 (10.5) | 11 (18.3) | 23 (6.3) | 168 (11.2) | |
| Astrocytoma, anaplastic | 203 (10.5) | <11 | 27 (7.4) | 172 (11.5) | |
| Glioblastoma | 1436 (74.6) | 43 (71.7) | 297 (81.2) | 1096 (73.0) | |
| Oligodendroglioma, anaplastic | 84 (4.4) | <11 | 16 (4.4) | 66 (4.4) | |
| Treatment | |||||
| Surgery only | 278 (14.4) | <11 | 61 (16.8) | 208 (13.8) | .334a |
| Surgery with adjuvant treatment | 1108 (57.6) | 33 (55.0) | 212 (58.4) | 863 (57.5) | .872 |
| Non-surgical treatment only | 244 (11.6) | <11 | 36 (10.0) | 200 (13.3) | .208a |
| No treatment | 295 (15.3) | 10 (16.7) | 54 (14.9) | 231 (15.4) | .931 |
| Treatment time, months | |||||
| Diagnosis to surgery | 0.3 (1.4) | 0.5 (0.7) | 0.2 (0.6) | 0.3 (1.6) | .592 |
Abbreviation: NOS, not otherwise specified.
Bold values are significant.
Percentages given out of total number of patients within each population classification unless otherwise specified. Categorical variables compared with Chi-square test. Continuous variables compared with ANOVA test. Categories with less than 11 patients are not explicitly listed to protect patients from possible identification.
aCategorical variables compared with Fisher-Freeman-Halton exact test.