Abstract
Background
Oral diseases remain among the most widespread non-communicable conditions globally, disproportionately affecting low- and middle-income populations. Despite the substantial and rising financial burden—estimated at US$ 298 billion in 2010—existing cost studies in dentistry often omit indirect costs and lack methodological consistency. These gaps hinder fair reimbursement, cost-effectiveness modeling, and equitable resource allocation. This scoping review aimed to map current methodologies for dental cost estimation, identify how frequently and by what means overhead costs are incorporated, extract standardized unit costs for common procedures, and assess the sources and valuation techniques underpinning these estimates.
Methods
Following an a priori protocol registered with the Isfahan University of Medical Sciences Ethics Committee (Approval Code: IR.MUI.RESEARCH.REC.1402.1), we conducted a comprehensive search across six major databases and gray literature sources. Studies were screened using the Participants–Concept–Context (PCC) framework. Eligible studies were original economic evaluations in dentistry that reported detailed cost data. Data extraction was performed using customized charting forms, and all reported costs were standardized to 2024 international dollars (Int’l $) using exchange rates, U.S. Consumer Price Index (CPI) data, and purchasing power parity (PPP) adjustments. Results are reported in accordance with the PRISMA-ScR guidelines.
Results
Out of 31,619 retrieved records, 124 studies met inclusion criteria. Most studies were conducted in urban, high-income settings and reported only direct costs (58.1%), while fewer accounted for overheads (41.9%). Advanced allocation techniques such as Activity-Based Costing (ABC) or Time-Driven ABC (TD-ABC) were used in less than 10% of studies. Bottom-up valuation was the predominant approach (72.5%). Unit costs for frequently reported procedures showed wide variation (e.g., surgical tooth removal: Int’l $6–501), driven by methodological and contextual heterogeneity.
Conclusions
Despite increasing interest in dental cost estimation, major gaps remain—especially in rural settings, overhead cost inclusion, and methodological transparency. Standardizing costing frameworks, piloting ABC/TD-ABC in real-world settings, and developing open-access dental cost repositories could substantially improve future economic evaluations and reimbursement equity. This review offers a comparative foundation for dentists, researchers, and policymakers to support value-based oral health planning.
Supplementary Information
The online version contains supplementary material available at 10.1186/s12903-025-06808-3.
Keywords: Costs and cost analysis, Dental economics, Dental fees, Health care costs, Dental care
Background
Oral diseases are among the most pervasive non-communicable conditions, affecting an estimated 3.9 billion people, roughly half of the world’s population. The World Health Organization (WHO) lists untreated caries in permanent teeth as the single most prevalent health problem, while severe periodontitis and complete tooth loss occupy positions within the top-twenty global burdens. Globally, direct spending on dental treatment was estimated at US $298 billion in 2010, approximately 4.6% of total healthcare expenditure—and is projected to rise steeply as populations age, restorative technologies proliferate, and aesthetic expectations increase [1, 2]. To effectively manage this staggering financial burden, health systems and policymakers require accurate evidence on costs.
Generating accurate cost evidence in dentistry, however, is far from straightforward. Studies diverge markedly based on two fundamental valuation strategies: top-down and bottom-up costing. Top-down approaches begin with a clinic’s total budget and split those expenses down to individual services. Bottom-up methods do the opposite, building a total cost by identifying and adding up every resource—like staff time and materials—used for a single patient. A major challenge in either approach is accounting for overhead costs: the essential inputs like administrative salaries, utilities, rent, and sterilization that keep a clinic functioning but cannot be traced to a single patient encounter. While the direct costs of a procedure are visible, these indirect overhead items can represent 15% to 60% of the true cost, making their allocation and measurement critical.
To tackle the critical task of overhead allocation, methodologies range from simple estimates to more precise, activity-based approaches. The most basic method involves using straightforward proportional rules, such as distributing rent and utility costs based on clinic floor space or staff numbers. However, to achieve greater accuracy, more advanced techniques have been developed. Activity-Based Costing (ABC), for instance, provides a more granular picture by identifying all clinical and administrative activities and assigning overheads based on how much each activity consumes those resources. A more recent variant, Time-Driven ABC (TD-ABC), streamlines this process further by using the duration of each task as the primary driver for cost allocation. While these advanced methods aim to calculate both direct and overhead costs and estimate a more accurate unit cost, the choice of methodology significantly impacts the final estimate, creating challenges for comparing costs across different studies.
Beyond allocation, dental economics researchers also utilize complementary frameworks, such as value-based cost-effectiveness analyses to integrate patient outcomes, break-even analyses to determine minimum operational viability, and model-based techniques (decision trees, Markov models) to simulate long-term cost trajectories under alternative clinical scenarios (see Table 3 for an overview of these cost estimation methods in Appendix 2) [3–7]. This methodological heterogeneity, spanning from foundational costing techniques to broader economic models, creates significant challenges for evidence synthesis and underscores the urgent need for a comprehensive scoping review.
Table 3.
Summary of findings on methodologies
| Method | Strengths | Limitations | Use cases |
|---|---|---|---|
| Activity-based costing (ABC) | Delivers granular cost tracking by linking expenses to specific clinical activities (e.g., materials, chair time, sterilization) | Requires considerable time investment and granular data collection; challenging in fast-paced clinical workflows | Cost transparency for discrete procedures (e.g., fillings, crowns) and resource optimization in high-volume dental clinics |
| Time-driven ABC (TD-ABC) | Captures time variability in clinical workflows (e.g., chairside minutes, staff multitasking); enables real-time adaptation to workflow variations | Demands integration with digital tools (e.g., practice management software); requires calibration for dental-specific time metrics | Multistage treatments (e.g., implant placements, orthodontic adjustments) and capacity planning in clinics with fluctuating patient volumes |
| Value-based cost-effectiveness analysis | Integrates patient-reported outcomes (e.g., oral health-related quality of life) with costs, emphasizing long-term value over episodic care | Relies on subjective metrics (e.g., OHIP-14 scores) that lack standardized valuation for decision-makers; struggles to quantify social determinants (e.g., socioeconomic disparities) | Prioritizing preventive care (e.g., fluoride programs) and chronic disease management (e.g., periodontal therapy); evaluating policy interventions for oral health equity |
| Break-even analysis | Provides a clear threshold for covering fixed costs (e.g., salaries, rent) in high-overhead dental settings; simplifies financial planning for high-margin procedures | Relies on unrealistic assumptions (linear cost-revenue relationships, static pricing); ignores market competition and demand variability | Evaluating practice startups (e.g., $500 k turnover target for suburban clinics) and new services (e.g., dental implants, in-house membership plans) |
| Model-based estimations | Integrates diverse datasets (e.g., Medicaid claims, fee schedules, demographics) to simulate long-term outcomes; employs advanced techniques (e.g., Markov models, decision trees) for granular cost projections | Vulnerable to data gaps (e.g., incomplete treatment histories) and heterogeneity in dental coding standards; requires calibration for procedure-specific variables (e.g., caries progression rates) | Predictive cost modeling (e.g., capitation rate design); policy evaluation (e.g., Medicaid reimbursement, water fluoridation programs); long-term sustainability analysis for chronic conditions (e.g., periodontitis) |
| Decision trees | Provides explainable, flowchart-like models to map clinical pathways (e.g., differential diagnosis of oral ulcers); supports transparent decision-making in time-constrained settings | Struggles with probabilistic outcomes (e.g., variable treatment responses) and oversimplifies multifactorial conditions (e.g., chronic pain syndromes) | Differential diagnosis (e.g., oral mucosal lesions); comparing treatment pathways (e.g., root canal vs. extraction, surgical vs. nonsurgical periodontal therapy) |
| Markov models | Simulates long-term disease progression (e.g., caries to pulpitis) and cost trajectories, enabling sustainability assessments of preventive vs. curative strategies | Requires precise transition probabilities (e.g., carries recurrence rates) and assumptions about static patient behavior; computationally intensive for multistate scenarios | Evaluating preventive programs (e.g., water fluoridation cost-effectiveness); projecting lifetime costs of chronic conditions (e.g., periodontal disease) |
For practicing dentists, this methodological complexity has tangible implications. A key example is the practice of pricing services according to empirically measured, comprehensive unit costs rather than historical or arbitrary tariffs. Alongside chair-time benchmarking and investment appraisal, depends critically on accurately knowing procedure-specific costs, inclusive of both direct clinical and indirect operational resources [8]. Similarly, researchers conducting economic studies cannot credibly model cost estimation if unit costs differ substantially merely because of methodological discrepancies [9]. Policymakers face a related challenge too, insurance tariffs and public subsidies that neglect overheads risk undercompensating providers, discouraging their participation, and ultimately exacerbating inequities in service access [10].
Previous literature has explored the economic dimensions of dentistry from several angles but has not yet mapped the foundational cost estimation methodologies themselves. Syntheses of prior research have largely focused on the cost-effectiveness of specific interventions, the determinants of service utilization, and patient preferences. A significant body of work has concentrated on single preventive interventions, with reviews consistently finding that community water fluoridation (CWF) and school-based programs using fluorides and sealants are cost-effective or even cost-saving [11–14]. Methodologically, these evaluations are dominated by cost-effectiveness analysis; a 2019 scoping review by Eow et al. found that 75% of full economic evaluations fell into this category [15]. Another research stream examines factors driving inequalities in dental services, showing that utilization is heavily influenced by individual determinants like age and race, social factors like education, and economic status such as income and insurance coverage [16]. This body of research shows that dental care is geographically concentrated in high-income countries. A third field uses Willingness-to-Pay (WTP) methods to gauge patient preferences, but reviews note this area has significant methodological weaknesses, such as the frequent use of convenience samples, that limit generalizability [17]. While these streams of research are valuable, they sidestep the fundamental question of how the costs of dental services are calculated. Even the most relevant prior reviews, which focused on full economic evaluations, emphasized solely the outcomes of economic evaluations rather than the underlying methods used for measuring the costs of inputs and resources.
This scoping review is justified by a critical gap in the literature, as no previous review has systematically examined all economic studies within dental practice with a cost estimation framework. Furthermore, there is no existing evidence that details how economic studies within dental practice categorize and calculate direct versus overhead costs, or the specific methods used to allocate them. Similarly, no prior study has undertaken the task of extracting and standardizing the unit costs for a wide variety of dental services as reported in the literature.
Therefore, this scoping review aims to map methodological approaches utilized in dental cost estimation; quantify the frequency and methods of overhead cost allocation; standardize reported unit costs to facilitate robust cross‐study comparisons using 2024 international dollars; and document valuation methods underpinning dental cost estimates. Through these objectives, we aim to illuminate methodological heterogeneity, highlight critical evidence gaps—particularly in rural and underserved contexts—and establish a transparent, comparative foundation for dentists and researchers interested in implementing rigorous economic evaluations and studies.
Materials and methods
Protocol and registration
This scoping review was conducted following an a priori protocol registered and approved by the ethics committee of Isfahan University of Medical Sciences (Approval Code: IR.MUI.RESEARCH.REC.1402.1; Date: April 9, 2023). Clinical trial number: not applicable, as this review did not involve human participants or clinical interventions.
Eligibility criteria
Eligibility criteria were structured using the Participants, Concept, Context (PCC) framework, with participants limited to studies explicitly evaluating the costs of dental services within healthcare systems, thus excluding those adopting societal or patient perspectives due to their broader cost implications. The concept included studies explicitly reporting detailed cost data, distinguishing direct and overhead (indirect) costs or providing unit costs for dental procedures; studies lacking detailed cost breakdowns or reporting solely clinical outcomes were excluded. The context encompassed all settings offering dental services (private practices, hospital-based services, public clinics, outreach/mobile units) across all specialties recognized by the American Dental Association (ADA), excluding studies unrelated to dentistry, such as general medical services. Additional criteria required studies to be original economic analyses (costing studies or partial economic evaluations) published in English or Persian, available as full-text articles online; systematic reviews, narrative reviews, commentaries, and editorials were excluded to maintain focus on primary economic data.
Information sources and search
A comprehensive search strategy was developed and conducted in October 2024 across six major electronic databases (PubMed, Scopus, Institute for Scientific Information (ISI) Web of Science, Ovid, Embase, and ProQuest) and Google Scholar for gray literature. The search combined controlled vocabulary (e.g., Medical Subject Heading (MeSH) terms) and free-text keywords, systematically covering cost-related concepts (e.g., cost analysis, economic evaluation, activity-based costing, micro-costing) and dental-specific terms (e.g., dental health services, orthodontics, prosthodontics). The full, replicable search strategy for PubMed and adaptations for other databases are provided in Appendix 1.
Selection of sources of evidence
All identified records were imported into Mendeley Reference Manager, with duplicates systematically removed. Two independent reviewers conducted pilot screening of randomly selected records to ensure consistency. Subsequently, title and abstract screening was independently conducted by both reviewers, guided strictly by the PCC-based eligibility criteria. Discrepancies were resolved through discussion or a third independent reviewer. Eligible studies progressed to full-text screening, applying identical inclusion/exclusion criteria. Reasons for exclusion at this stage (e.g., non-original studies, unavailable full-text, non-English/Persian language, societal or patient perspective, inadequate cost data) were carefully documented. The final selection process is comprehensively illustrated in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 flow diagram depicted in Fig. 1.
Fig. 1.
PRISMA 2020 flow diagram
Data charting process
A standardized, structured data-charting process was developed using customized extraction forms created in Microsoft Excel (online version). Given the absence of pre-existing standardized forms specific to dental cost estimation, two tailored forms were designed to comprehensively capture data aligned explicitly with the study’s objectives. Data form 1 gathered general information, study characteristics, and detailed methodological data on cost identification, measurement, and valuation. Form 2 was specifically dedicated to systematically collecting and organizing reported unit costs across various dental procedures.
Data items
The data-charting forms systematically captured key variables to support the descriptive and comparative analysis of included studies. Form 1 collected detailed bibliographic data (authors, publication year, country, journal), contextual factors (geographical location: urban, rural, or mixed), dental specialties (according to ADA classifications), and a structured assessment of costing methodologies used. Specifically, methodological variables included the type of cost evaluated (direct, overhead), overhead cost allocation methods (traditional vs. activity-based), costing approaches (top-down, bottom-up), the source of cost data (primary data, secondary sources, standardized cost references, expert opinions), price years, and reported currencies. Form 2 focused exclusively on recording detailed unit cost data for dental procedures, structured in a matrix format to facilitate direct comparisons between studies. Each distinct dental procedure formed one row, and each included study was represented in separate columns, clearly displaying unit cost variability across different studies.
Critical appraisal of individual sources of evidence
Given the descriptive nature and broad methodological scope of this scoping review, a critical appraisal of the methodological quality of individual studies was not conducted, consistent with standard scoping review methodology.
Synthesis of results
Extracted data were managed, analyzed, and synthesized using Microsoft Excel to ensure comprehensive descriptive and comparative analysis. The synthesis focused on identifying key trends in the literature regarding dental specialties and settings, methodological approaches used for cost estimation (direct vs. overhead costs, top-down vs. bottom-up methods, and overhead allocation methods), and the diversity of data sources utilized. To standardize costs across studies, we converted the reported values into international dollars (int’l $) for 2024. This involves three steps: converting the original currency to the U.S. dollar (USD) via historical exchange rates, adjusting for U.S. inflation to align with 2024 prices based on U.S. consumer price index (CPI) data from sources such as the U.S. Bureau of Labor Statistics, and then applying the 2024 purchasing power parity (PPP) conversion factor. This approach ensures that all costs reflect equivalent global purchasing power, enabling consistent cross-country and temporal comparisons. The results were presented in detailed tabular and graphical formats, clearly illustrating cost variability, methodological preferences, and trends across different contexts and procedures.
Results
Selection of sources of evidence
The initial search of databases retrieved 31,619 records (PubMed, Scopus, ISI Web of Science, Ovid, Embase, ProQuest, and Google Scholar). After removing duplicates (n = 17,224), 14,395 unique records underwent initial screening by two independent reviewers. During this stage, 13,973 studies unrelated to dental service costing were excluded. Consequently, 442 studies proceeded to full-text review. Of these, 25 reports lacked accessible full-text versions, leaving 417 studies for eligibility assessment. Subsequently, 216 articles were excluded for not being original economic studies, 26 for language issues, 10 due to insufficient costing details, and 20 due to societal/patient perspectives. Ultimately, 124 studies met all eligibility criteria and were included for final analysis (see Fig. 1 for the PRISMA flowchart).
Characteristics of included studies
Included studies were published between 1973 and 2024, with a median publication year of 2017. A pronounced increase in publication frequency is evident from 2010 onward, reflecting the growing interest in cost estimation within dental services and highlights peak publication activity between 2016 and 2022. Geographically, the United States contributed the largest share (27.4%) of studies, followed by Brazil (9.6%), Germany (7.2%), and England (7.2%). Most studies were conducted in urban settings (85.4%), with public/community dental clinics (27.4%) being the most common study sites, followed by academic/university-affiliated clinics (21.7%) and hospital-based departments (14.5%), as detailed in Appendix 2 (Table 4). This diverse setting distribution reflects both global research interest and variations in service delivery models that impact dental cost estimation.
Table 4.
Characteristics of the included studies
| Characteristic | Category | Number of studies (n = 124) | Percentage (%) |
|---|---|---|---|
| Publication year | Range | [1973]–[2024] | |
| Median | [2017] | ||
| Dental specialty | Dental public health | 51 | (41.1) |
| Prosthodontics | 24 | (19.3) | |
| [Other Specialties] | 49 | (39.5) | |
| Geographic location | United States | 34 | (27.4) |
| Brazil | 12 | (9.6) | |
| Germany | 9 | (7.2) | |
| England | 9 | (7.2) | |
| [Other Countries] | 60 | (48) | |
| Setting | Public or Community Dental Clinic | 34 | (27.4) |
| Academic/University-Affiliated Dental Clinic | 27 | (21.7) | |
| Hospital-Based Dental Department | 18 | (14.5) | |
| [Other settings] | 45 | (36.2) | |
| Geographic context | Urban | 106 | (85.4) |
| Rural | 9 | (8) | |
| Mixed | 10 | (6.4) |
Dental specialties and subfields
The distribution of included studies across dental specialties shows dental public health dominated the landscape, comprising 41.1% of studies and encompassing subfields such as health policy and advocacy (19 studies), epidemiology (18 studies), and community-based prevention programs (14 studies). Prosthodontics was the second most represented specialty at 19.4%, split between removable (13 studies) and fixed prosthodontics (11 studies). Other specialties were less frequently analyzed: Oral/Maxillofacial Surgery (9.7%), Endodontics (7.3%), Orthodontics/Dentofacial Orthopedics (7.3%), Pediatric Dentistry (4.8%), Periodontics (5.6%), and Dental Anesthesiology (2.4%). Detailed counts and references for these subfields are provided in appendix 2 (Table 5).
Table 5.
Distribution of disciplines included across specialties
| Dental specialty | Subfield within specialty | Frequency |
|---|---|---|
| Health policy and advocacy | 19 (8, 26, 32–34, 36, 41, 48, 53, 67–76) | |
| Dental public health | Epidemiology | 18 (18, 37, 38, 44, 46, 50, 54, 77–87) |
| Community-based prevention programs | 14 (24, 43, 45, 88–98) | |
| Prosthodontics | Removable prosthodontics | 13 (35, 99–110) |
| Fixed prosthodontics | 11 (6, 19, 39, 40, 49, 111–116) | |
| Endodontics | Root canal therapy | 7 (21, 117–122) |
| Endodontic surgery | 1 (55) | |
| Trauma management | 1 (120) | |
| Oral/Maxillofacial radiology | Diagnostic imaging | 3 (27, 123, 124) |
| Corrective jaw surgery (Orthognathic Surgery) | 7 (3, 25, 29, 31, 125–127) | |
| Oral/Maxillofacial surgery | Facial trauma reconstruction | 4 (42, 128–130) |
| Dental implant surgery | 1 (28) | |
| Orthodontics/Dentofacial orthopedics | Braces and clear aligners (Arch alignment) | 5 (4, 52, 131–133) |
| Craniofacial Orthopedics | 4 (30, 134–136) | |
| Pediatric dentistry | Restorative pediatric dentistry | 5 (20, 55, 137–139) |
| Behavioral management | 1 (140) | |
| Periodontics | Gum disease treatment (Periodontal disease treatment) | 6 (7, 47, 51, 141–143) |
| Implantology | 1(51) | |
| Dental anesthesiology | General anesthesia | 3 (23, 144, 145) |
Cost types, allocation, and valuation methods
Among the 124 included studies, direct costs—covering clinical procedures, materials, and professional fees—were reported in 72 studies (58.1%), while overhead costs (administrative support, utilities, facility maintenance) appeared in 52 studies (41.9%). Traditional overhead allocation methods (e.g., apportioning by hours or floor space) were most common (45 studies; 36.3%), with advanced techniques such as Activity-Based Costing (ABC) used in just 7 studies (5.6%). For valuation, the bottom-up approach prevailed, applied in 90 studies (72.5%) to provide granular, itemized cost assessments, whereas the top-down method—relying on aggregated financial data—was used in 33 studies (26.6%). Detailed frequencies for cost types, overhead allocation, and valuation methods are summarized in Table 1. This table presents the frequency of studies for each characteristic. The column “Number of studies (citation numbers)” shows the total count of studies in that category, with the associated reference numbers listed in parentheses for transparency and traceability.
Table 1.
Characteristics of costs
| Characteristic | Category | Number of studies (citation numbers) |
|---|---|---|
| Type of included costs | Direct costs | 72 [1, 18–87], [146] |
| Overhead costs | 52 [2, 10, 11, 88–136] | |
| Not applicable | 72 [1, 18–87], [146] | |
| Overhead cost allocation method | Traditional cost allocation | 45 [10, 11, 88, 90, 91, 93, 95, 96, 98–121, 123–129, 131–136] |
| Activity-based costing (ABC) | 7 [2, 89, 92, 94, 97, 122, 130] | |
| Valuation method | Bottom-up | 90 [1, 10, 11, 18, 20–23, 25–30, 32–36, 38, 41, 43–53, 55–73, 75, 76, 78–82, 84–87, 90, 93, 95, 96, 98, 99, 101, 106, 109, 112, 114–120, 123–126, 128, 129, 131, 133–135], [146] |
| Top-down | 33 [2, 19, 24, 31, 37, 39, 40, 42, 74, 77, 83, 88, 89, 91, 92, 94, 97, 100, 102–105, 107, 108, 110, 111, 113, 121, 122, 127, 130, 132, 136] | |
| Not applicable | 1 [54] |
Methodological landscape of economic evaluations
The included studies were categorized based on their economic evaluation type and the analytical approach used. A clear distinction was found between studies performing a comprehensive comparison of alternatives versus those focused only on costing. Of the 124 studies, a majority (64%, n = 79) were identified as Full economic evaluations, where two or more interventions were compared on both costs and consequences. The remaining 36% (n = 45) were Partial Economic Evaluations (costing studies). Among full economic evaluations, Cost-effectiveness analysis (CEA) was the most common specific design, while Cost analysis or Cost description was the most frequent among partial evaluations.
Analysis of methodological approaches
The analytical approaches used to conduct economic evaluations in the included literature varied significantly, with studies being primarily retrospective (41%), model-based (31%), or trial-based (28%). A strong correlation was observed between the evaluation type and the analytical approach used. Full economic evaluations, which compare the value of different interventions, frequently used model-based or trial-based analytical approaches. In contrast, partial economic evaluations, which focus on quantifying costs, were overwhelmingly conducted using retrospective analysis of historical data. Trial-based evaluations are those where economic data on costs and consequences are collected prospectively from participants enrolled in a single clinical study, most often a Randomized controlled trial (RCT). This approach, often called a "piggyback" study, provides high-quality evidence by linking costs and outcomes directly to the same patient cohort under controlled conditions. CEA was used to compare costs and clinical effectiveness of interventions. For example, the trial-based CEA by Hichens et al. (2007) used a large RCT to show that vacuum-formed orthodontic retainers were a "dominant" strategy—both less costly and clinically more effective—than Hawley retainers, providing strong evidence for a change in clinical practice [137]. Cost-Minimization Analysis (CMA) was the appropriate design when clinical trials assumed no significant difference in the effectiveness of the compared interventions. The study by Joda & Brägger (2015) is a key example; using a powerful crossover RCT design, the authors demonstrated that a digital workflow for implant crowns was significantly less costly in terms of time and materials than the conventional workflow, for a clinically equivalent outcome [138].
Hybrid trial-based and modeling approaches
Some studies used trial data as the primary input for a simulation model to analyze uncertainty. For instance, Olegário et al. (2020) conducted an RCT comparing different glass ionomer cements for ART restorations. They then used the cost and survival data from their trial to power a Monte Carlo simulation model, which confirmed that the higher initial cost of the standard material was justified by its superior long-term survival, making it the most cost-effective option [139].
Model-based evaluations
Model-based evaluations use mathematical or computer-based simulations to project costs and outcomes over time, often for a hypothetical cohort of patients. This approach is essential for estimating the long-term value of interventions when long-term trial data is unavailable. The most common model types were Markov models and decision trees. Markov Models simulate the movement of a cohort between different health states (e.g., "healthy," "diseased," "treated") over a series of time cycles, making them ideal for chronic diseases. The CUA by Naved et al. (2024) is a classic example, using a Markov model to project the lifetime cost per Quality-Adjusted Life-Year (QALY) gained for different endodontic treatments [140]. Similarly, Schwendicke et al. (2017) used a Markov model powered by real cohort data to analyze the cost-effectiveness of different strategies for managing periodontally affected molars [141]. Decision Trees map out short-term clinical decisions and their potential outcomes based on branching probabilities. The CEA by Jameson et al. (2007) provides a clear example, using a simple decision tree to calculate the average cost of sedation by incorporating the probability and high cost of treatment failure that would require a subsequent hospital-based general anesthetic [142]. Budget Impact Analysis (BIA) modelling was used to forecast the financial impact of an intervention on a large healthcare system. For example, Du et al. (2021) used a BIA model to estimate the total annual cost savings to the entire Chinese dental care system if the population increased its use of sugar-free gum [143]. Breakeven Analysis was used to determine the point at which an investment becomes profitable. Murdock et al. (2010) used this approach to model the number of Medicaid patients an orthodontic practice would need to treat to cover its overhead costs, directly addressing a key financial barrier to provider participation [4].
Cost estimation (costing) studies
Cost estimation studies, which focused on quantifying costs rather than comparing value, predominantly used retrospective analysis of existing data. Cost-of-Illness (COI) Studies aimed to quantify the total economic burden of a disease. A key example is McArdle et al. (2016), who built a cost projection model to estimate the total annual cost to the UK's NHS of treating a specific third molar complication, thereby making a policy argument for prevention [144]. Another unique example is Colthirst et al. (2013), who performed a retrospective COI study by analyzing military records to determine the total operational cost of dental emergencies in a combat zone, which included the cost of soldiers' lost time. Cost-Description and Cost-Analysis Studies focused on the costs of specific services or technologies, using a variety of costing methods [145]. A prime example of high-quality costing is the prospective micro-costing study by Dassonville et al. (2017), which meticulously tracked every resource used to determine the cost of a single complex surgical procedure [88]. In contrast, Jones et al. (2019) used a model-based cost-analysis to assess the profitability of different office-based surgical procedures from a private practice perspective [89].
This methodological diversity demonstrates that the field of dental health economics uses a wide and sophisticated range of analytical tools to answer different types of clinical and policy questions, from assessing the long-term value of a new technology to quantifying the real-world cost of a single procedure.
Advanced costing methodologies: ABC and TD-ABC
Among the included studies, a small but significant subset (n = 8) moved beyond traditional costing methods to employ advanced accounting techniques for more precise cost allocation. These studies utilized either ABC or its more recent evolution, TD-ABC to provide a granular analysis of resource consumption.
Activity-based costing
ABC is a top-down-micro costing method that identifies all the discrete activities required to deliver a service and allocates costs to those specific activities. The total cost of the service is the sum of the costs of all activities consumed, providing a more accurate picture than traditional methods that use broad overhead percentages. The study by Tewfik et al. (2021) provides a clear example of ABC in a hospital setting. To determine the true cost of orthognathic surgery, the authors used their hospital's existing ABC system. This system calculated the cost of a single patient's hospitalization by summing the costs from three distinct "activity centers" the patient passed through: the inpatient ward, the surgery/operating room, and other hospital services. Each center had its own detailed cost items (e.g., medical personnel, nursing staff, drugs, devices). This allowed for a precise calculation of the total direct hospital cost, which was then compared to the inadequate national tariff, highlighting a major policy issue [18].
Time-driven activity-based costing
TD-ABC is a refined version of ABC that simplifies the process by focusing on the single most valuable resource: time. It involves two steps: 1) calculating a "capacity cost rate" (e.g., cost per minute) for each resource (such as a clinician, an assistant, or a specific clinical space), and 2) multiplying that rate by the amount of time the resource was used for a particular patient or procedure. This method was used in two key studies to analyze the cost of complex surgical planning, demonstrating its adaptability to different study designs, for example a Prospective Study by Ganske et al. (2021) used TD-ABC to compare the cost of two different presurgical infant orthopedic techniques. Researchers prospectively followed patients and, using stopwatches, timed every single step of the clinical encounter in real-time. They created detailed process maps of the patient journey and calculated the capacity cost rate for each staff member and facility type. The final cost was determined by multiplying the time spent on each activity by the corresponding cost rate. This provided a highly accurate, real-world cost for each treatment pathway [90]. Another study design was employed In a Retrospective Study by Resnick et al. (2016) also used TD-ABC but applied it retrospectively. They analyzed the records of patients who had undergone orthognathic surgery and created a process map for two different planning workflows (standard vs. virtual). For each case, they calculated the time spent on each activity. They then used national salary and overhead data to determine the capacity cost rates for the personnel involved. This allowed them to perform a direct, paired comparison of the two workflows for each patient, demonstrating that the virtual planning method was significantly less costly due to a large reduction in high-cost surgeon time [91]. The use of these advanced costing methodologies, while not common across the entire body of literature, represents a clear move toward more precise, context-sensitive cost estimation in dentistry, driven by the need for both detailed resource tracking and a more accurate understanding of the value of different clinical workflows [18, 19, 90, 92, 93].
Unit costs
The 124 studies reported unit prices for 87 distinct dental services, and the resulting dataset shows pronounced price heterogeneity. Variation stems from differing costing methods, country-specific economic conditions, and even how individual procedures are defined (e.g., “denture fabrication” or “extraction” can involve different clinical steps across studies). Consequently, only a handful of services appear often enough, and with sufficient consistency, to support pooled estimates. Key observations demonstrate high variability in most services which exhibited wide cost ranges (e.g., dental sealant: Int’l 7.2–100.7 or tooth removal by surgery: Int’l6.33–501.5), reflecting contextual and methodological differences. A subset of services (e.g., scaling, PFM crown per teeth) showed narrower price ranges, suggesting greater consistency in cost reporting or procedural standardization and Relative homogeneity. All estimates were converted to 2024 International Dollars to improve comparability, though contextual factors (e.g., local labor costs, subsidies) remain critical for interpretation. Detailed information on unit costs is illustrated in Table 2. This table lists up to four cost estimates for each type of dental service reported. The columns “Cost (Int $) Study A–D” represent the first, second, third, and fourth studies that provided a unit price for each type of dental service and the number inside the parenthesis is the study’s citation number in our bibliography.
Table 2.
Reported unit costs for dental services (Presented in Int’l $)
| Type of service | Cost (Int $) Study A (citation number) | Cost (Int $) Study B (citation number) | Cost (Int $) Study C (citation number) | Cost (Int $) Study D (citation number) |
|---|---|---|---|---|
| Denture Fabrication | 1,372 [20] | 539 [21] | 577 [94] | - |
| PFM crown per teeth | 219 [19] | 263 [95] | 144 [96] | 439 [22] |
| Extraction | 38.5 [23] | 32.5 [95] | 162 [24] | 198 [97] |
| Dental Sealant | 7.2 [98] | 59.9 [93] | 100.7 [25] | 8.5 [26] |
| Large Amalgam Restorations | 38.3 [99] | 116 [8] | 109.2 [27] | 141.1 [28] |
| Panoramic Radiograph | 23.7 [20] | 290 [29] | 37 [100] | 125.9 [101] |
| Examination | 44.35 [20] | 93.89 [99] | 43.5 [30] | 95 [97] |
| Tooth Removal by surgery | 54.2 [19] | 6.33 [21] | 501.5 [89] | 264 to 440 [144] |
| Scaling | 23.95 [19] | 30.47 [23] | 32.25 [93] | 31.12 [99] |
| Atraumatic Restorative Treatment (ART) | 268.28 [25] | 25.07 [31] | 20.96 [32] | - |
Discussion
Summary of evidence
This scoping review of 124 studies shows that published work on dental-care costs has grown rapidly since 2010 yet remains concentrated in high-income countries and urban centers. Most investigations report only direct clinical expenses; fewer than half measure overheads, and fewer than one in ten use advanced allocation techniques such as ABC or Time-Driven ABC. Consequently, unit prices for identical procedures diverge widely—for example, surgical tooth removal ranged from Int’l $ 6 to $ 501. For dentists, more complete and standardized cost data would enable accurate fee setting, investment decisions, and efficiency benchmarking. For oral-health researchers, consistent reporting would strengthen economic evaluations and multicenter trial budgets. Policymakers could use robust, overhead-inclusive estimates to calibrate reimbursement schedules, safeguard preventive programs, and direct subsidies to underserved regions.
Our finding of a sharp post-2010 rise in dental-economics publications echoes the bibliometric trends noted by Eow et al. (2019) and Beck et al. (2022) who link this growth to escalating health-care expenditure and greater policy demand for cost evidence [15, 33]. Consistent with earlier reviews, high-income nations (United States, Germany, United Kingdom) continue to dominate the field, a pattern commonly attributed to stronger research infrastructure and funding [34]. Nevertheless, the increasing presence of middle-income countries—particularly Brazil and Iran—signals a welcome broadening of geographic scope, albeit still largely confined to urban settings. Like Kalman et al. (2015) and Špacírová et al. (2022), we confirm that most dental studies report only direct costs; fewer than 40% quantify overheads, leading to systematic under-estimation of true economic burden [9, 35]. Traditional proportional allocation remains the norm, while advanced techniques such as ABC and TD-ABC appear in fewer than 10% of studies—a gap also highlighted in wider health-care costing literature [102, 103]. This underutilization persists despite evidence that micro-costing improves accuracy and decision relevance. Our results complement Mogyorosy et al. in showing bottom-up as the preferred valuation strategy [36]. Yet practical constraints—time, data access—often force hybrid approaches that blend micro- and gross-cost elements. The resulting methodological heterogeneity, coupled with divergent data sources and currency conventions, produces the wide unit-cost ranges observed here and in prior work by Lessard et al.[104]. Conversion to international dollars mitigates but does not eliminate cross-country variability, mirroring concerns raised about PPP adjustments in health settings [37, 105, 106].
Although micro-costing (patient-level resource tracing) and gross costing (aggregated averages) are often presented as mutually exclusive [107], the studies we reviewed seldom adhered to each category. Many papers combined detailed time-tracking for chairside labor—characteristic of micro-costing—with broad national fee schedules for overheads, blurring the boundary between the two approaches. Fee structures themselves are opaque: some charges derive from in-house accounting systems, while others reflect bundled market tariffs, and authors rarely disclose the calibration process. Even longitudinal “micro-costing” studies must apportion shared resources such as sterilization or building costs by top-down rules, because measuring each patient’s exact share is impractical. With no accepted threshold for how granular data must be to qualify as micro-costing, any strict dichotomy risks misclassification. We therefore focused on valuation method—bottom-up versus top-down—and highlighted explicitly hybrid methods. This choice avoids oversimplifying a field where fully pure micro- or gross-cost studies are the exception rather than the rule.
Several limitations should be considered when interpreting these findings. The analysis included only English- and Persian-language studies, and without formal quality appraisal of the primary literature, methodological weaknesses could influence the synthesis. Significant heterogeneity existed in costing methodologies; studies often blended micro- and gross-costing elements without standardized definitions or transparent fee-schedule construction. Furthermore, inconsistent definitions of cost terms (e.g., “direct,” “indirect”) and diverse data sources, ranging from hospital ledgers to national fee schedules, likely contributed to cross-study variability. Currency conversions relied on World-Bank PPP factors, which may mask intra-country price variations, lag behind inflation, and potentially distort health-sector prices. Finally, while grey literature was searched, some unpublished work may have been omitted, and the exclusive focus on cost data precludes any conclusions regarding cost-effectiveness.
With these limitations in mind, three priority gaps emerge. First, rural and low-resource settings are almost absent from current costing evidence; dedicated multicenter studies that capture overheads in community clinics are needed to inform equitable reimbursement. Second, fewer than 10% of studies used ABC or TD-ABC; pilot projects that implement these methods—ideally aligned with the Consolidated Health Economic Evaluation Reporting Standards (CHEERS) 2022 reporting checklist would test feasibility and generate reference protocols. Third, cost data are reported in heterogeneous formats. Creating an open, dental-specific cost repository with standard fields (currency year, allocation method, cost components) would enable meta-analysis and benchmarking. Future work should also embed sensitivity analyses for currency conversion and inflation to improve cross-country comparability and pair economic data with clinical outcomes to guide value-based oral-health policy.
Conclusion
Reliable, overhead-inclusive costing is foundational to fair reimbursement, efficient clinic management, and credible oral-health research. Yet current evidence remains fragmented, with indirect costs under-reported and precise allocation methods seldom used. By adopting standardized reporting frameworks, expanding studies to rural and underserved settings, and piloting ABC/TD-ABC in routine practice, the dental community can generate the robust, comparable cost data that dentists, researchers, and policymakers need to deliver financially sustainable, high-quality oral care.
Supplementary Information
Below is the link to the electronic supplementary material.
Acknowledgements
The authors gratefully acknowledge the institutional support from the school of dentistry, Isfahan university of medical sciences. The authors of this study adhered to established academic and ethical standards in research and writing. The study does not attribute authorship to any AI-generated content, and all contributions have been appropriately acknowledged within the manuscript.
Abbreviations
- ABC
Activity-based costing
- TD-ABC
Time-driven activity-based costing
- US $
United States Dollar
- WHO
World Health Organization
- ADA
American Dental Association
- CPI
Consumer price index
- Int’l $
International dollar
- ISI
Institute for Scientific Information
- MeSH
Medical subject headings
- PCC
Participants, concept, context
- PPP
Power purchasing parity
- PRISMA
Preferred Reporting Items for Systematic Reviews and Meta-Analyses
- USD
United States Dollar
- CHEERS
Consolidated Health Economic Evaluation Reporting Standards
- PFM
Porcelain-fused-to-metal
Appendix 1
PubMed:


Scopus:


ISI Web of sciences






Embase Search:




Appendix 2
Author contributions
PT made substantial contributions to the analysis of data and drafting of the manuscript. MR contributed significantly to the conception and design of the work and substantively revised the manuscript. FR played a key role in the design of the study and the interpretation of data. All authors have approved the submitted version of the manuscript and agree to be personally accountable for their own contributions. They also ensure that any questions related to the accuracy or integrity of any part of the work, even those in which they were not personally involved, are appropriately investigated, resolved, and documented in literature.
Funding
No external funding or grants were received for the research, authorship, or publication of this study.
Data availability
Data generated or analyzed during this study are included in this published article and its supplementary files. Additionally, any further data or details supporting the findings of this study will be made available at reasonable request to the corresponding author. If required, data will be submitted to the journal or relevant repositories as needed.
Declarations
Ethics approval and consent to participate
The study adhered to a priori protocol, approved by the Ethics Committee of Isfahan University of Medical Sciences (Approval Code: IR.MUI.RESEARCH.REC.1402.1, Date: April 9, 2023). This study does not involve any individual person’s data in any form, including personal details, images, or videos. As a scoping review, the research is based entirely on previously published literature and does not include case reports or patient-specific information requiring consent. Consent to participate is “not applicable”.
Consent for publication
Consent for publication is “not applicable”.
Competing interests
The authors declare no competing interests.
Footnotes
Publisher’s note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
References
- 1.Listl S, Galloway J, Mossey PA, Marcenes W. Global economic impact of dental diseases. J Dent Res. 2015;94(10):1355–61. [DOI] [PubMed] [Google Scholar]
- 2.Peres MA, Macpherson LMD, Weyant RJ, Daly B, Venturelli R, Mathur MR, et al. Oral diseases: a global public health challenge. Lancet. 2019;394(10194):249–60. [DOI] [PubMed] [Google Scholar]
- 3.Lin LO, Kalmar CL, Vu GH, Zimmerman CE, Humphries LS, Swanson JW, et al. Value-based analysis of virtual versus traditional surgical planning for orthognathic surgery. J Craniofac Surg. 2020;31(5):1238–42. [DOI] [PubMed] [Google Scholar]
- 4.Murdock JE, Phillips C, Beane R, Quinonez R. Break-even analysis of Medicaid vs fee for service in orthodontic practice: North Carolina as a case study. Am J Orthod Dentofacial Orthop. 2010;137(3):334–9. [DOI] [PubMed] [Google Scholar]
- 5.Zhu LW, Wang RX, Zhang Y, Zhan JY, Lu HX, Chen X. A cost-effectiveness analysis of fluoride varnish application in preventing root caries in elderly persons: a Markov simulation study. BMC Oral Health. 2024;24(1):483. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 6.Teranishi Y, Arai K, Baba S. Cost-utility analysis of molar single implant versus fixed dental prosthesis. Int J Prosthodont. 2019;32(1):75–81. [DOI] [PubMed] [Google Scholar]
- 7.Anuwar AHK, Ng CW, Safii SH, Saub R, Ab-Murat N. Modelling the national economic burden of non-surgical periodontal management in specialist clinics in Malaysia using a markov model. BMC Oral Health. 2024;24(1):346. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 8.Tan SS, Ken Redekop W, Rutten FF. Costs and prices of single dental fillings in Europe: a micro-costing study. Health Econ. 2008;17(S1):S83–93. [DOI] [PubMed] [Google Scholar]
- 9.Špacírová Z, Epstein D, García-Mochón L, Rovira J, de Olry Labry Lima A, Lima A, et al. A general framework for classifying costing methods for economic evaluation of health care. Eur J Health Econ. 2020;21(4):529–42. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 10.Lal A, Moodie M, Peeters A, Carter R. Inclusion of equity in economic analyses of public health policies: systematic review and future directions. Aust N Z J Public Health. 2018;42(2):207–13. [DOI] [PubMed] [Google Scholar]
- 11.Worsley D, Robinson P, Marshman Z. Access to urgent dental care: a scoping review. Community Dent Health. 2017;34(1):19–26. [DOI] [PubMed] [Google Scholar]
- 12.Dawett B, Deery C, Banerjee A, Papaioannou D, Marshman Z. A scoping literature review on minimum intervention dentistry for children with dental caries. Br Dent J. 2022. [DOI] [PubMed]
- 13.Amilani U, Carter HE, Senanayake S, Hettiarachchi RM, McPhail SM, Kularatna S. A scoping review of cost-effectiveness analyses of school-based interventions for caries. Community Dent Oral Epidemiol. 2020;48(5):357–63. [DOI] [PubMed] [Google Scholar]
- 14.Farrokhi F, Farrokhi F, Mohebbi SZ, Khami MR. A scoping review of the impact of COVID-19 on dentistry: financial aspects. BMC Oral Health. 2024;24(1):945. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 15.Eow J, Duane B, Solaiman A, Hussain U, Lemasney N, Ang R, et al. What evidence do economic evaluations in dental care provide? A scoping review. Community Dent Health. 2019;36(2):118–25. [DOI] [PubMed] [Google Scholar]
- 16.Pezeshki BS, Kazemian A, Tahani B. Distribution of national dental public health researches of Iran until 2023. J Dent Med. 2024;37.
- 17.Saadatfar N, Jadidfard MP. An overview of the methodological aspects and policy implications of willingness-to-pay studies in oral health: a scoping review of existing literature. BMC Oral Health. 2020;20:1–12. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 18.Tewfik K, Chiarelli P, Battaglia S, Catanzaro S, Pederneschi N, Copelli C, et al. Adequacy of the Italian National Tariff for orthognathic surgery: a cost analysis using the activity based costing (ABC) method. J Craniofac Surg. 2021;32(3):840–3. [DOI] [PubMed] [Google Scholar]
- 19.Aliakbar Esfahani A, Azarkhosh H. Calculation of cost of dental services by activity based costing (ABC) method in a naval clinic in Tehran, Iran. J Mar Med. 2020;1(4):204–14. [Google Scholar]
- 20.Ahmad R, Zul NA, Mohtar SA, Tennant M, Mohd-Dom TN. Revisiting a funding model for university-led dental clinics: the case of complete denture fabrication. J Dent Indones. 2020;27(2):61–6. [Google Scholar]
- 21.Helöe LA. Evaluation of a subsidized dental program among rural Norwegians. Community Dent Oral Epidemiol. 1974;2(2):40–9. [PubMed] [Google Scholar]
- 22.Shaheen R, Al Nasser H, Al Salem M, Al Abdulwahab M, Al Nasser A, Al Saffan AD. Financial costs comparison between replacing a tooth with a dental implant or with a fixed dental prosthesis or saving the tooth with endodontic therapy in Riyadh and Al-Hasa. Saudi J Oral Sci. 2018;5(2):119–24. [Google Scholar]
- 23.Alade OT, Arikawe OA, Lawal FB, Taiwo JO. The cost minimization analysis of an outreach dental service: a pilot study at Akinyele local Government Area in Nigeria. Ann Ib Postgrad Med. 2016;14(1):35–40. [PMC free article] [PubMed] [Google Scholar]
- 24.Han J, Liau I, Bayetto K, May B, Goss A, Sambrook P, et al. The financial burden of acute odontogenic infections: the South Australian experience. Aust Dent J. 2020;65(1):39–45. [DOI] [PubMed] [Google Scholar]
- 25.Molete M, Chola L, Hofman K. Costs of a school-based dental mobile service in South Africa. BMC Health Serv Res. 2016;16:1–6. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 26.Boachie MK, Molete M, Hofman K, Thsehla E. Cost-effectiveness of dental caries prevention strategies in South African schools. BMC Oral Health. 2023;23(1):814. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 27.Azimi Y, Ghorbani Z, Rojhanian T. Comparing the cost of dental services during Covid-19 pandemic and earlier by activity-based costing. J Dent Med. 2022;35(0):121–35. [Google Scholar]
- 28.Bakshi A, Khan R, Ahmed B. Private practice pricing in the Birmingham region. Prim Dent J. 2019;8(1):34–7. [DOI] [PubMed] [Google Scholar]
- 29.Salomon D, Heidel RE, Kolokythas A, Miloro M, Schlieve T. Does restriction of public health care dental benefits affect the volume, severity, or cost of dental-related hospital visits? J Oral Maxillofac Surg. 2017;75(3):467–74. [DOI] [PubMed] [Google Scholar]
- 30.Mariño R, Tonmukayakul U, Manton D, Stranieri A, Clarke K. Cost-analysis of teledentistry in residential aged care facilities. J Telemed Telecare. 2016;22(6):326–32. [DOI] [PubMed] [Google Scholar]
- 31.da Mata C, Allen PF, Cronin M, O’Mahony D, McKenna G, Woods N. Cost-effectiveness of ART restorations in elderly adults: a randomized clinical trial. Community Dent Oral Epidemiol. 2014;42(1):79–87. [DOI] [PubMed] [Google Scholar]
- 32.Garbim JR, Saihara CS, Olegário IC, Hesse D, Araujo MP, Bonifácio CC, et al. 2-year survival and cost analysis of occlusoproximal ART restorations using encapsulated glass ionomer cement in primary molars: a randomized controlled trial. BMC Oral Health. 2024;24(1):647. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 33.Beck N, Choi SE, Barrow J. The need for high-quality economic evaluations in dentistry. Int Dent J. 2022;72(3):266–8. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 34.Păduraru O, Moroșanu A, Păduraru CȘ, Cărăușu EM, editors. Healthcare management: a bibliometric analysis based on the citations of research articles published between 1967 and 2020. Healthcare; 2022. MDPI. [DOI] [PMC free article] [PubMed]
- 35.Kalman N, Hammill B, Schulman K, Shah B. Hospital overhead costs: the neglected driver of health care spending? J Health Care Finance. 2015;41(4).
- 36.Mogyorosy Z, Smith P. The main methodological issues in costing health care services: A literature review. 2005.
- 37.Jevdjevic M, Listl S. Global, regional, and country-level economic impacts of oral conditions in 2019. J Dent Res. 2025;104(1):17–21. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 38.Balbinot GdS, Celeste RK, Leitune VCB, Collares FM. Implementation in restorative treatments in public health: a 10-year analysis of resin composite procurement in Brazil. Cad Saude Publ. 2022;38(3):e00118321. [DOI] [PubMed] [Google Scholar]
- 39.Dudko Y, Kruger E, Tennant M. National dental waitlists: what would it take to reset to zero? Aust Health Rev. 2015;40(3):277–81. [DOI] [PubMed] [Google Scholar]
- 40.Gotowka TD, Johnson ES, Gotowka CJ. Costs of providing dental services to adult mentally retarded: a preliminary report. Am J Public Health. 1982;72(11):1246–50. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 41.Milnes AR, Rubin CW, Karpa M, Tate R. A retrospective analysis of the costs associated with the treatment of nursing caries in a remote Canadian aboriginal preschool population. Community Dent Oral Epidemiol. 1993;21(5):253–60. [DOI] [PubMed] [Google Scholar]
- 42.Doherty N, Horowitz PA, Crakes G. Real costs of dental care in private and public practices. Med Care. 1980;18(1):96–109. [DOI] [PubMed] [Google Scholar]
- 43.Doykos J 3rd. Comparative cost and time analysis over a two-year period for children whose initial dental experience occurred between ages 4 and 8 years. Pediatr Dent. 1997;19(1):61–2. [PubMed] [Google Scholar]
- 44.Gisselsson H, Birkhed D, Björn A-L. Effect of a 3-year professional flossing program with chlorhexidine gel on approximal caries and cost of treatment in preschool children. Caries Res. 1994;28(5):394–9. [DOI] [PubMed] [Google Scholar]
- 45.Hietasalo P, Seppä L, Niinimaa A, Kallio J, Lahti S, Hausen H. Post-trial costs, clinical outcomes, and dental service utilization after a randomized clinical trial for caries control among Finnish adolescents. Eur J Oral Sci. 2010;118(3):265–9. [DOI] [PubMed] [Google Scholar]
- 46.Johhnson B, Serban N, Griffin PM, Tomar SL. Projecting the economic impact of silver diamine fluoride on caries treatment expenditures and outcomes in young U.S. children. J Public Health Dent. 2019;79(3):215–21. [DOI] [PubMed] [Google Scholar]
- 47.Khouja T, Smith KJ. Cost-effectiveness analysis of two caries prevention methods in the first permanent molar in children. J Public Health Dent. 2018;78(2):118–26. [DOI] [PubMed] [Google Scholar]
- 48.Lamster IB, Malloy KP, DiMura PM, Cheng B, Wagner VL, Matson JM, et al. Preventive dental care is associated with improved health care outcomes and reduced costs for Medicaid members with diabetes. Front Dent Med. 2022;3:952182. [Google Scholar]
- 49.Lexomboon D, Karlsson P, Adolfsson J, Ekbom A, Naimi-Akbar A, Bahmanyar S, et al. Consumption and direct costs of dental care for patients with head and neck cancer: a 16-year cohort study. PLoS ONE. 2017;12(8):e0182877. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 50.Li M, Donkor IK, Shao R, Hsieh S, Jiang X, Hong L, et al. Effects of Alzheimer’s disease and related dementias on dental care usage and economic burden in older adults: a cross-sectional study. BMJ Open. 2023;13(6):e068944. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 51.Tannous KW, George A, Ahmed MU, Blinkhorn A, Dahlen HG, Skinner J, et al. Economic evaluation of the Midwifery Initiated Oral Health-Dental Service programme in Australia. BMJ Open. 2021;11(8):e047072. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 52.Utriainen P, Widström E. Economic aspects of dental care in Finnish health centers. Community Dent Oral Epidemiol. 1990;18(5):235–8. [DOI] [PubMed] [Google Scholar]
- 53.Bergström E, Lingström P, Hakeberg M, Gahnberg L, Sköld U. Caries and costs: an evaluation of a school-based fluoride varnish programme for adolescents in a Swedish region. Community Dent Health. 2016;33(2):138–44. [PubMed] [Google Scholar]
- 54.Calderone JJ, Mueller L. The cost of sealant application in a state dental disease prevention program. J Public Health Dent. 1983;43(3):249–54. [DOI] [PubMed] [Google Scholar]
- 55.Cronin J, Moore S, Harding M, Whelton H, Woods N. A cost-effectiveness analysis of community water fluoridation for schoolchildren. BMC Oral Health. 2021;21(1):158. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 56.Falasco RF, Henderson WG. Estimated reduction in dental expenditures for lowans through preventive programs. J Am Dent Assoc. 1973;86(3):627–34. [DOI] [PubMed] [Google Scholar]
- 57.Hughes ML, Legler DW. Costs, benefits, and management considerations of a prepaid student dental health plan. J Am Coll Health Assoc. 1979;27(6):293–6. [DOI] [PubMed] [Google Scholar]
- 58.Kroon J, Van Wyk PJ. A retrospective view on the viability of water fluoridation in South Africa to prevent dental caries. Community Dent Oral Epidemiol. 2012;40(5):441–50. [DOI] [PubMed] [Google Scholar]
- 59.O’Rourke C, Attrill M, Holloway P. Cost appraisal of a fluoride tablet programme to Manchester primary schoolchildren. Community Dent Oral Epidemiol. 1988;16(6):341–4. [DOI] [PubMed] [Google Scholar]
- 60.Siruta KJ, Simmer-Beck ML, Ahmed A, Holt LA, Villalpando-Mitchell T, Gadbury-Amyot CC. Extending oral health care services to underserved children through a school-based collaboration: part 3–a cost analysis. J Dent Hyg. 2013;87(5):289–98. [PubMed] [Google Scholar]
- 61.Werbrouck A, Schmidt M, Annemans L, Duyck J, Janssens B, Simoens S, et al. Oral healthcare delivery in institutionalised older people: a health-economic evaluation. Gerodontology. 2022;39(2):107–20. [DOI] [PubMed] [Google Scholar]
- 62.Cavalcante DFB, Pereira AC, Cavalcanti YW, Probst LF, Ambrosano GMB. Overdentures as an alternative to conventional dentures: a micro-costing analysis for public health service in Brazil. Cien Saude Colet. 2021;26(8):3335–44. [DOI] [PubMed] [Google Scholar]
- 63.Cristache CM, Ionescu C, Cristache G, Ionescu I, Iliescu AA, Burlibasa M. A 5-year prospective randomised, clinical trial on the efficiency of two different attachment systems as retention for implant-supported mandibular overdenture. Radiographic assessment, cost analysis and final evaluation of treatment’s success. Metal Int. 2009;14:27–34. [Google Scholar]
- 64.Della Vecchia MP, Leles CR, Cunha TR, Ribeiro AB, Sorgini DB, Muglia VA, et al. Mini-implants for mandibular overdentures: cost-effectiveness analysis alongside a randomized trial. JDR Clin Transl Res. 2018;3(1):47–56. [DOI] [PubMed] [Google Scholar]
- 65.Ghiasi P, Petrén S, Chrcanovic B, Larsson C. Comparative cost analysis of different prosthetic rehabilitations for the edentulous maxilla: early results from a randomized clinical pilot study. BDJ Open. 2022;8(1):8. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 66.Hartmann R, de Menezes Bandeira ACF, de Araújo SC, McKenna G, Brägger U, Schimmel M, et al. Cost-effectiveness of three different concepts for the rehabilitation of edentulous mandibles: Overdentures with 1 or 2 implant attachments and hybrid prosthesis on four implants. J Oral Rehabil. 2020;47(11):1394–402. [DOI] [PubMed] [Google Scholar]
- 67.Hofmann E, Behr M, Handel G. Frequency and costs of technical failures of clasp-and double crown-retained removable partial dentures. Clin Oral Investig. 2002;6:104–8. [DOI] [PubMed] [Google Scholar]
- 68.Miyayasu A, Kanazawa M, Jo A, Sato Y, Minakuchi S. Cost-effectiveness analysis of two impression methods for the fabrication of mandibular complete dentures. J Dent. 2018;68:98–103. [DOI] [PubMed] [Google Scholar]
- 69.Stoker G, Wismeijer D, Van Waas M. An eight-year follow-up to a randomized clinical trial of aftercare and cost-analysis with three types of mandibular implant-retained overdentures. J Dent Res. 2007;86(3):276–80. [DOI] [PubMed] [Google Scholar]
- 70.Mangano FG, Cianci D, Pranno N, Lerner H, Zarone F, Admakin O. Trueness, precision, time-efficiency and cost analysis of chairside additive and subtractive versus lab-based workflows for manufacturing single crowns: an in vitro study. J Dent. 2024;141:104792. [DOI] [PubMed] [Google Scholar]
- 71.Maryniuk GA, Schweitzer SO, Braun RJ. Replacement of amalgams with crowns: a cost-effectiveness analysis. Community Dent Oral Epidemiol. 1988;16(5):263–7. [DOI] [PubMed] [Google Scholar]
- 72.Naved N, Khowaja AR, Umer F. Restoration of endodontically treated teeth: a cost-effectiveness analysis of an endocrown versus a complete crown. J Prosthet Dent. 2024. [DOI] [PubMed]
- 73.Naved N, Umer F, Khowaja AR. Irreversible pulpitis in mature permanent teeth: a cost-effectiveness analysis of pulpotomy versus root canal treatment. BMC Oral Health. 2024;24(1):285. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 74.DiPaolo M, Townsend J, Peng J, McTigue DJ, Azadani EN. Characteristics, treatment outcomes and direct costs of tooth avulsion in children treated at a major hospital. Dent Traumatol. 2023;39(3):240–7. [DOI] [PubMed] [Google Scholar]
- 75.Milojević AD, Janković SM, Đonović NŽ, Stefanović SM, Artinović VM, Golijanin RD. Analysis of the costs of treating dry socket. Acta Stomatol Naissi. 2015;31(71):1443–54. [Google Scholar]
- 76.Goodson A, Parmar S, Ganesh S, Zakai D, Shafi A, Wicks C, et al. Printed titanium implants in UK craniomaxillofacial surgery. Part II: perceived performance (outcomes, logistics, and costs). Br J Oral Maxillofac Surg. 2021;59(3):320–8. [DOI] [PubMed] [Google Scholar]
- 77.Mazzola F, Smithers F, Cheng K, Mukherjee P, Low T-HH, Ch’ng S, et al. Time and cost-analysis of virtual surgical planning for head and neck reconstruction: a matched pair analysis. Oral Oncol. 2020;100:104491. [DOI] [PubMed] [Google Scholar]
- 78.Sonesson M, Naraghi S, Bondemark L. Cost analysis of two types of fixed maxillary retainers and a removable vacuum-formed maxillary retainer: a randomized controlled trial. Eur J Orthod. 2022;44(2):197–202. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 79.Borrie FR, Elouafkaoui P, Bearn DR. A Scottish cost analysis of interceptive orthodontics for thumb sucking habits. J Orthod. 2013;40(2):145–54. [DOI] [PubMed] [Google Scholar]
- 80.Cunningham SJ, Sculpher M, Sassi F, Manca A. A cost-utility analysis of patients undergoing orthognathic treatment for the management of dentofacial disharmony. Br J Oral Maxillofac Surg. 2003;41(1):32–5. [DOI] [PubMed] [Google Scholar]
- 81.Kumar S, Williams AC, Sandy JR. Orthognathic treatment: how much does it cost? Eur J Orthod. 2006;28(6):520–8. [DOI] [PubMed] [Google Scholar]
- 82.Sankar P, Gurunathan D, Ravindran V. Analysis of the cost associated with the treatment of early childhood caries in children aged 2–6 years. Indian J Forensic Med Toxicol. 2020;14(4):5964–72. [Google Scholar]
- 83.Da Silva K, Lionel A, O’Brien JM, Wright KD, Raazi M. The Use of General Anesthesia for Pediatric Dentistry in Saskatchewan: a Retrospective Study. J Can Dent Assoc. 2022;88:m9. [PubMed] [Google Scholar]
- 84.Holsinger DM, Wells MH, Scarbecz M, Donaldson M. Clinical evaluation and parental satisfaction with pediatric zirconia anterior crowns. Pediatr Dent. 2016;38(3):192–7. [PubMed] [Google Scholar]
- 85.Lalwani K, Kitchin J, Lax P. Office-based dental rehabilitation in children with special healthcare needs using a pediatric sedation service model. J Oral Maxillofac Surg. 2007;65(3):427–33. [DOI] [PubMed] [Google Scholar]
- 86.Green LK, Lee JY, Roberts MW, Anderson JA, Vann WF Jr. A cost analysis of three pharmacologic behavior guidance modalities in pediatric dentistry. Pediatr Dent. 2018;40(7):419–24. [PubMed] [Google Scholar]
- 87.Rashewsky S, Parameswaran A, Sloane C, Ferguson F, Epstein R. Time and cost analysis: pediatric dental rehabilitation with general anesthesia in the office and the hospital settings. Anesth Prog. 2012;59(4):147–53. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 88.Dassonville O, Bozec A, Château Y, Reyt E, Devauchelle B, Louis M-Y, et al. Multicenter prospective micro-costing study evaluating mandibular free-flap reconstruction. Eur Arch Otorhinolaryngol. 2017;274:1103–11. [DOI] [PubMed] [Google Scholar]
- 89.Jones JP, Ellis E III. Are office-based oral and maxillofacial surgical procedures profitable? A benefit–cost analysis. J Oral Maxillofac Surg. 2019;77(11):2205–14. [DOI] [PubMed] [Google Scholar]
- 90.Ganske IM, Sanchez K, Le E, Langa OC, Sharif-Askary B, Ross E, et al. Time-driven, activity-based costing of presurgical infant orthopedics: a critical component of establishing value of Latham appliance and nasoalveolar molding. Plast Reconstr Surg. 2021;147(3):444–54. [DOI] [PubMed] [Google Scholar]
- 91.Resnick CM, Inverso G, Wrzosek M, Padwa BL, Kaban LB, Peacock ZS. Is there a difference in cost between standard and virtual surgical planning for orthognathic surgery? J Oral Maxillofac Surg. 2016;74(9):1827–33. [DOI] [PubMed] [Google Scholar]
- 92.Febrian F, Lukman S, Hardisman H, Suhairi S. Cost calculation of dental service at Pratama Clinic using activity-based costing method in Padang, West Sumatera, Indonesia. J Int Oral Health. 2020;12(1):46–51. [Google Scholar]
- 93.Nourizadeh TP. The cost of all types of dental services presented by Farman Farmaeian Comprehensive Health Services Center at Tehran University of Medical Sciences using activity-based costing method in 1397. Hakim J. 2019;22(4):319–28. [Google Scholar]
- 94.Smith BJ, Helgeson M, Prosa B, Finlayson TL, Orozco M, Asgari P, et al. Longitudinal analysis of cost and dental utilization patterns for older adults in outpatient and long-term care settings in Minnesota. PLoS ONE. 2020;15(5):e0232898. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 95.Goetz K, Winkelmann W, Steinhäuser J. Assessment of oral health and cost of care for a group of refugees in Germany: a cross-sectional study. BMC Oral Health. 2018;18:1–7. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 96.Pires A, Poletto-Neto V, Chisini L, Schwendicke F, Pereira-Cenci T. Post-retained restorations: a cost-minimization analysis nested in a randomized clinical trial. Oper Dent. 2021;46(3):255–62. [DOI] [PubMed] [Google Scholar]
- 97.Atkins CY, Thomas TK, Lenaker D, Day GM, Hennessy TW, Meltzer MI. Cost-effectiveness of preventing dental caries and full mouth dental reconstructions among Alaska Native children in the Yukon-Kuskokwim delta region of Alaska. J Public Health Dent. 2016;76(3):228–40. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 98.Goldman AS, Chen X, Fan M, Frencken JE. Methods and preliminary findings of a cost-effectiveness study of glass-ionomer-based and composite resin sealant materials after 2 yr. Eur J Oral Sci. 2014;122(3):230–7. [DOI] [PubMed] [Google Scholar]
- 99.Kakudate N, Morita M, Sugai M, Nagayama M, Fukuhara S, Kawanami M, et al. Comparison of dental practice income and expenses according to treatment types in the Japanese insurance system. Jpn Dent Sci Rev. 2010;46(1):4–10. [Google Scholar]
- 100.Schneider D, Sancho-Puchades M, Schober F, Thoma D, Hämmerle C, Jung R. A randomized controlled clinical trial comparing conventional and computer-assisted implant planning and placement in partially edentulous patients. Part 3: time and cost analyses. Int J Periodontics Restorative Dent. 2019. 10.11607/prd.4146. [DOI] [PubMed] [Google Scholar]
- 101.Björksved M, Ryen L, Lindsten R, Bazargani F. Open and closed surgical exposure of palatally displaced canines: a cost-minimization analysis of a multicentre, randomized controlled trial. Eur J Orthod. 2021;43(5):498–505. [DOI] [PubMed] [Google Scholar]
- 102.Keel G, Savage C, Rafiq M, Mazzocato P. Time-driven activity-based costing in health care: a systematic review of the literature. Health Policy. 2017;121(7):755–63. [DOI] [PubMed] [Google Scholar]
- 103.da Silva Etges APB, Cruz LN, Notti RK, Neyeloff JL, Schlatter RP, Astigarraga CC, et al. An 8-step framework for implementing time-driven activity-based costing in healthcare studies. Eur J Health Econ. 2019;20(8):1133–45. [DOI] [PubMed] [Google Scholar]
- 104.Lessard C. Complexity and reflexivity: two important issues for economic evaluation in health care. Soc Sci Med. 2007;64(8):1754–65. [DOI] [PubMed] [Google Scholar]
- 105.Zhou LL, Ampon-Wireko S, Wireko Brobbey E, Dauda L, Owusu-Marfo J, Kachie Tetgoum AD, editors. The role of macroeconomic indicators on healthcare cost. In: Healthcare; 2020. MDPI. [DOI] [PMC free article] [PubMed]
- 106.Multiple A. Purchasing Power Parity (PPP) Conversion Factor—World Bank Data. World Bank; 2025.
- 107.Tan SS, Bouwmans CA, Rutten FF, Hakkaart-van RL. Update of the Dutch manual for costing in economic evaluations. Int J Technol Assess Health Care. 2012;28(2):152–8. [DOI] [PubMed] [Google Scholar]
- 108.Arevalo O, Saman DM, Bonaime A, Skelton J. Mobile dental units: leasing or buying? A dollar-cost analysis. J Public Health Dent. 2010;70(3):253–7. [DOI] [PubMed] [Google Scholar]
- 109.Hens MJ, Alonso-Ferreira V, Villaverde-Hueso A, Abaitua I, de la Posada Paz M. Cost-effectiveness analysis of burning mouth syndrome therapy. Community Dent Oral Epidemiol. 2012;40(2):185–92. [DOI] [PubMed] [Google Scholar]
- 110.Lukman S, Sari DP. Comparative study of unit cost-analysis among Urban and Rural Dental Primary Health Services in Padang City, Indonesia. J Clin Diagn Res. 2019;13(3).
- 111.Mac Giolla Phadraig C, Nunn J, Guerin S, Normand C. Should we provide oral health training for staff caring for people with intellectual disabilities in community based residential care? A cost-effectiveness analysis. Eval Program Plann. 2016;55:46–54. [DOI] [PubMed] [Google Scholar]
- 112.Macêdo MSR, Chaves SCL, Fernandes ALdC. Investments and costs of oral health care for family health care. Rev Saude Publ. 2016;50:41. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 113.Mialhe FL, Pereira AC, Meneghim Mde C, Tagliaferro EP, Pardi V. Occlusal tooth surface treatment plans and their possible effects on oral health care costs. Oral Health Prev Dent. 2009;7(3):211–6. [PubMed] [Google Scholar]
- 114.Anopa Y, McMahon AD, Conway DI, Ball GE, McIntosh E, Macpherson LM. Improving child oral health: cost analysis of a national nursery toothbrushing programme. PLoS ONE. 2015;10(8):e0136211. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 115.Vrbič V, Košmelj B. Cost analysis of 3 years of topical fluoride application. Community Dent Oral Epidemiol. 1978;6(5):269–72. [DOI] [PubMed] [Google Scholar]
- 116.Otake R, Kanazawa M, Iwaki M, Soeda Y, Hada T, Katheng A, et al. Patient-reported outcome and cost-effectiveness analysis of milled and conventionally fabricated complete dentures in a university clinic: a retrospective study. J Prosthet Dent. 2024;131(2):227–32. [DOI] [PubMed] [Google Scholar]
- 117.Russo LL, Zhurakivska K, Guida L, Chochlidakis K, Troiano G, Ercoli C. Comparative cost-analysis for removable complete dentures fabricated with conventional, partial, and complete digital workflows. J Prosthet Dent. 2024;131(4):689–96. [DOI] [PubMed] [Google Scholar]
- 118.Vecchia MP, Regis RR, Cunha TR, de Andrade IM, da Matta JC, de Souza RF. A randomized trial on simplified and conventional methods for complete denture fabrication: cost analysis. J Prosthodont. 2014;23(3):182–91. [DOI] [PubMed] [Google Scholar]
- 119.Wetzels JWG, Meijer GJ, Koole R, Adang EM, Merkx MA, Speksnijder CM. Costs and clinical outcomes of implant placement during ablative surgery and postponed implant placement in curative oral oncology: a five-year retrospective cohort study. Clin Oral Implants Res. 2017;28(11):1433–42. [DOI] [PubMed] [Google Scholar]
- 120.Corcodel N, Zenthöfer A, Setz J, Rammelsberg P, Hassel AJ. Estimating costs for shade matching and shade corrections of fixed partial dentures for dental technicians in Germany: a pilot investigation. Acta Odontol Scand. 2011;69(5):319–20. [DOI] [PubMed] [Google Scholar]
- 121.Joda T, Gintaute A, Brägger U, Ferrari M, Weber K, Zitzmann NU. Time-efficiency and cost-analysis comparing three digital workflows for treatment with monolithic zirconia implant fixed dental prostheses: a double-blinded RCT. J Dent. 2021;113:103779. [DOI] [PubMed] [Google Scholar]
- 122.Schwendicke F, Müller A, Seifert T, Jeggle-Engbert L-M, Paris S, Göstemeyer G. Glass hybrid versus composite for non-carious cervical lesions: survival, restoration quality and costs in randomized controlled trial after 3 years. J Dent. 2021;110:103689. [DOI] [PubMed] [Google Scholar]
- 123.Zitzmann N, Krastl G, Weiger R, Kühl S, Sendi P. Cost-effectiveness of anterior implants versus fixed dental prostheses. J Dent Res. 2013;92(12_suppl):183S-S188. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 124.Schwendicke F, Stolpe M. Secondary treatment for asymptomatic root canal treated teeth: a cost-effectiveness analysis. J Endod. 2015;41(6):812–6. [DOI] [PubMed] [Google Scholar]
- 125.Koch M, Tegelberg Å, Eckerlund I, Axelsson S. A cost-minimization analysis of root canal treatment before and after education in nickel–titanium rotary technique in general practice. Int Endod J. 2012;45(7):633–41. [DOI] [PubMed] [Google Scholar]
- 126.Oliveira SCM, Floriano I, Tedesco TK, Gimenez T, Imparato JCP, Calvo AFB. Cost analysis of endodontic treatment in primary teeth: results from a randomized clinical trial. Braz Oral Res. 2021;35:e126. [DOI] [PubMed] [Google Scholar]
- 127.Graft BM, Sickles EA. A cost analysis comparing xeroradiography to film technics for intraoral radiography. J Public Health Dent. 1986;46(2):96–105. [DOI] [PubMed] [Google Scholar]
- 128.Christell H, Birch S, Horner K, Rohlin M, Lindh C, The SEDENTEXCT Consortium. A framework for costing diagnostic methods in oral health care: an application comparing a new imaging technology with the conventional approach for maxillary canines with eruption disturbances. Community Dent Oral Epidemiol. 2012;40(4):351–61. [DOI] [PubMed] [Google Scholar]
- 129.Ballard DH, Mills P, Duszak R Jr., Weisman JA, Rybicki FJ, Woodard PK. Medical 3D printing cost-savings in orthopedic and maxillofacial surgery: cost analysis of operating room time saved with 3D printed anatomic models and surgical guides. Acad Radiol. 2020;27(8):1103–13. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 130.Xia JJ, Phillips CV, Gateno J, Teichgraeber JF, Christensen AM, Gliddon MJ, et al. Cost-effectiveness analysis for computer-aided surgical simulation in complex cranio-maxillofacial surgery. J Oral Maxillofac Surg. 2006;64(12):1780–4. [DOI] [PubMed] [Google Scholar]
- 131.Benito D, Michel MC, Thakkar PG, Goodman JF, Sadeghi N, Joshi AS. A cost effective custom dental guard for transoral robotic surgery. J Robot Surg. 2020;14:91–4. [DOI] [PubMed] [Google Scholar]
- 132.Elhennawy K, Jost-Brinkmann PG, Manton DJ, Paris S, Schwendicke F. Managing molars with severe molar-incisor hypomineralization: a cost-effectiveness analysis within German healthcare. J Dent. 2017;63:65–71. [DOI] [PubMed] [Google Scholar]
- 133.Prabhu NT, Nunn JH, Evans DJ. A comparison of costs in providing dental care for special needs patients under sedation or general anaesthesia in the North East of England. London: SAGE Publications; 2006. [DOI] [PubMed] [Google Scholar]
- 134.Souto MLS, Carrer FCA, Braga MM, Pannuti CM. Smoking cessation therapy is a cost-effective intervention to avoid tooth loss in Brazilian subjects with periodontitis: an economic evaluation. BMC Oral Health. 2021;21(1):616. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 135.Pretzl B, Wiedemann D, Cosgarea R, Kaltschmitt J, Kim TS, Staehle HJ, et al. Effort and costs of tooth preservation in supportive periodontal treatment in a German population. J Clin Periodontol. 2009;36(8):669–76. [DOI] [PubMed] [Google Scholar]
- 136.Schwendicke F, Biffar AS, Graetz C. Long-term treatment costs for aggressive periodontitis in a German population. J Clin Periodontol. 2017;44(12):1245–52. [DOI] [PubMed] [Google Scholar]
- 137.Hichens L, Rowland H, Williams A, Hollinghurst S, Ewings P, Clark S, et al. Cost-effectiveness and patient satisfaction: Hawley and vacuum-formed retainers. Eur J Orthodont. 2007;29(4):372–8. [DOI] [PubMed] [Google Scholar]
- 138.Joda T, Brägger U. Digital vs. conventional implant prosthetic workflows: a cost/time analysis. Clin Oral Implants Res. 2015;26(12):1430–5. [DOI] [PubMed] [Google Scholar]
- 139.Olegário IC, de Miranda Ladewig N, Hesse D, Bonifácio CC, Braga MM, Imparato JCP, et al. Is it worth using low-cost glass ionomer cements for occlusal ART restorations in primary molars? 2-year survival and cost analysis of a randomized clinical trial. J Dent. 2020;101:103446. [DOI] [PubMed] [Google Scholar]
- 140.Naved N, Umer F, Khowaja AR. Cost-effectiveness analysis of regenerative endodontics versus MTA apexification. JDR Clin Transl Res. 2024;9(3):231–8. [DOI] [PubMed] [Google Scholar]
- 141.Schwendicke F, Stolpe M, Graetz C. Cost comparison of prediction-based decision-making for periodontally affected molars. J Clin Periodontol. 2017;44(11):1145–52. [DOI] [PubMed] [Google Scholar]
- 142.Jameson K, Averley P, Shackley P, Steele J. A comparison of the’cost per child treated’at a primary care-based sedation referral service, compared to a general anaesthetic in hospital. Br Dent J. 2007;203(6):E13-E. [DOI] [PubMed] [Google Scholar]
- 143.Du S, Zhang C, Wang W, Liu J, Yuan C, Yu Y, et al. The economic benefits of increased sugar-free chewing gum in China: a budget impact analysis. BMC Oral Health. 2021;21(1):436. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 144.McArdle LW, Patel N, Jones J, McDonald F. The mesially impacted mandibular third molar: the incidence and consequences of distal cervical caries in the mandibular second molar. Surgeon. 2018;16(2):67–73. [DOI] [PubMed] [Google Scholar]
- 145.Colthirst PM, Berg RG, DeNicolo P, Simecek JW. Operational cost analysis of dental emergencies for deployed US Army personnel during operation Iraqi freedom. Mil Med. 2013;178(4):427–31. [DOI] [PubMed] [Google Scholar]
- 146.Craig JR, Tataryn RW, Sibley HC, Mason WD, Deuel JA, Loyd GE, Nerenz DR, Goyal P. Expected costs of primary dental treatments and endoscopic sinus surgery for odontogenic sinusitis. Laryngoscope. 2022;132(7):1346–55. 10.1002/lary.29825 [DOI] [PubMed]
Associated Data
This section collects any data citations, data availability statements, or supplementary materials included in this article.
Supplementary Materials
Data Availability Statement
Data generated or analyzed during this study are included in this published article and its supplementary files. Additionally, any further data or details supporting the findings of this study will be made available at reasonable request to the corresponding author. If required, data will be submitted to the journal or relevant repositories as needed.

