Table 2.
Key information used for screening potential targets
| Protein | Charge | XCorr | Identified both | Location |
|---|---|---|---|---|
| TOM40 | 3 | 5.42 | Yes | Outer mitochondrial membrane |
| QCR6 | 2 | 1.48 | Yes | Inner mitochondrial membrane |
| DTX1 | 2 | 2.37 | No | Cytoplasm, nucleus |
| ZNF24 | 2 | 2.12 | Yes | Nucleus |
| NID2 | 4 | 1.93 | No | Secreted protein |
| LTBP4 | 3 | 1.90 | No | Secreted protein |
| MALT1 | 3 | 1.59 | Yes | Cytoplasm, nucleus |
| PKHA8 | 2 | 1.35 | No | Golgi apparatus |
| EXOSX | 2 | 1.09 | No | Cytoplasm, nucleus |
| VP13A | 2 | 1.02 | No | Membrane protein |
| YD021 | 2 | 0.94 | No | Unknown |
| CA094 | 2 | 0.78 | No | Unknown |
| GASR | 2 | 0.75 | No | Cell membrane |
The reliability criteria for protein identification by mass spectrometry are as follows: charge = 2, XCorr >2.2; charge = 3, XCorr >3.75. XCorr: reliability score of the spectrum. Entries in bold represent high-confidence peptides that were alkylated (carbamidomethylated) in the DMSO control group and modified by JB in the JB treatment group.